syspharm

[Robert Koch-Institut @rki_de]

Modelling study shows high efficacy of #PrEP in women countries with high #HIV prevalence. Risk of infection could be reduced by more than 90%. Publication of an international research team led by the #RKI in @NatureMedicine.
https://t.co/OKovfSdZy0

[Nature Medicine @NatureMedicine]

Modeling shows that antiretroviral treatment as pre-exposure prophylaxis (PrEP) can be highly effective in cisgender women at preventing #HIV-1 acquisition, but underscores the need to understand the barriers that limit PrEP adherence in women. https://t.co/q2t0JwLhQU

[syspharm @SystemPharm]

We just submitted our comprehensive analysis of #truvada based #prep efficacy against #HIV infection in women: https://t.co/5pnrLlr7OH. We hope that the work will clarify apparent mis-conceptions regarding gender-differences in PrEP efficacy and Prep adherence demands.

[syspharm @SystemPharm]

Just uploaded our comprehensive analysis of systematic sequencing errors in Oxford #nanopore Technology-based direct #rna sequencing (
@seq_rna). https://t.co/2lOIvOvCIO. Hope this work will contribute to the further development of the technique and #transcriptome analysis.

[NatureStructMolBiol @NatureSMB]

New work by Redmond Smyth lab @Helmholtz_HIRI: Comprehensive functional and structural probing of the HIV-1 5’ untranslated region reveals novel interactions that regulate RNA dimerization, Pr55Gag binding and genome packaging into virions. #openaccess https://t.co/YEfq6xPWBM

[Linneweber Lab @LinneweberLab]

Our Forschungsgruppe RobustCircuit is finally official! Thanks to @dfg_public and our speaker @HiesingerLab and all members from #Berlin @Wernet_Lab @SystemPharm, Sigrist lab, Petzoldt lab, Baum lab, Schreiber lab and #Mainz @marion_silies @crlttmrtll, Ryglewski lab Duch lab.

[syspharm @SystemPharm]

Excited to share our latest article published in @ploscompbiol: https://t.co/zyheaNMp11 #ploscompbiolauthor . We developed a new method to estimate #Prep efficacy against #HIV infection for arbitrary drug-dosing schemes

[syspharm @SystemPharm]

We could finally show that hot flies have less synapses, or: Brain connectivity inversely scales with developmental temperature in Drosophila https://t.co/iPBSG07B7y

[MATHplus @MATHplusBerlin]

Congratulations to the @rki_de team led by MATH+ PI Max von Kleist on the publication in @NatureComms! They used a method, GInPipe, to estimate #SARS_CoV_2 incidences and the number of unreported cases. It is based on publicly available viral genomes.
➡️ https://t.co/A2MzUNIGQf

[syspharm @SystemPharm]

For the World AIDS day, the BMBF published an article regarding our work on HIV-pre-exposure prophylaxis https://t.co/AXZXOb4XWg

[syspharm @SystemPharm]

Investigation of a Limited but Explosive COVID-19 Outbreak in a German Secondary School @SSRN https://t.co/1YoqJzxaF5

[syspharm @SystemPharm]

Check out our new method for the stochastic simulation of spreading dynamics on adaptive networks! https://t.co/CdJ4uy4GI4

[syspharm @SystemPharm]

Read our latest #research on [#Covid_19], published with @SpringerNature in [@NatureComms]. We developed #methods for incidence estimation from #SARSCoV2 #Genomics data: https://t.co/kHnSy8AMGP

[syspharm @SystemPharm]

https://t.co/5eOHk9gRuV

[syspharm @SystemPharm]

Excited to share our new paper on the caveats and challenges in inferring #GeneRegulatoryNetworks from #singlecell RNAseq temporal data. Thanks to our colleagues @AiBiology and
@ZuseInstitute !!

[syspharm @SystemPharm]

We developed some very efficient methods for estimating the efficacy of arbitray time-dependent prophylaxis against acquiring infection https://t.co/GXpbxY6AW2

[syspharm @SystemPharm]

We submitted a few new papers on modelling PrEP efficacy: a) Mechanisms of combinatorial efficacy of Truvada and b) efficient numerical methods to estimate PrEP efficacy. The latter may be used in a health App to help PrEP users to plan and monitor individual protection levels...

[syspharm @SystemPharm]

Check out our novel method for estimating SARS-CoV-2 incidence only from sequence data; medrxiv viewer https://t.co/QooP9VyK3l

[syspharm @SystemPharm]

medrxiv viewer https://t.co/31pu2gzceE

[syspharm @SystemPharm]

The Lab developed novel Tools to fight SARS-CoV2, which will be presented at the COVID Dynamics and Evolution conference: https://t.co/U3BMfq6JZi. a) A Software to compute quarantine, isolation and testing strategies and b) an incidence estimator based on SARS-CoV2 genetics.