UCL MBPhD

The official Twitter account of the unique UCL MBPhD programme.

[UCL MBPhD @UCL_MBPhD]

Discussion [2/2]
📌DREAMseq study shows order matters in oncogene-mutant melanoma: immunotherapy before targeted therapy
📌Longer follow-up period needed to analyse clinical durability
📌Further studies including patients with brain metastases would also be beneficial

[UCL MBPhD @UCL_MBPhD]

#JournalClub @claudialee_ & guest expert @pdnpdnpdn discussed Tawbi et al. @NEJM https://t.co/908mUaTW69
Relatlimab–nivolumab (anti-LAG3 & anti-PD1) was superior to nivolumab alone in untreated advanced melanoma. Median PFS 10.1 vs 4.6 months, hazard ratio 0.75.

[UCL MBPhD @UCL_MBPhD]

Discussion [1/2]
📌Could rel-nivo benefit non-responders to ipilimumab (anti-CTLA4)-nivolumab (CheckMate-067 study)?
📌If patient is not fit enough for ipi-nivo, consider rel-nivo? Treatment-related adverse events in 59% ipi-nivo patients vs 19% rel-nivo patients

[UCL MBPhD @UCL_MBPhD]

The UCL MBPhD programme is recruiting for Sep 2022 and Sep 2023! Come to our open day from 13:00 – 15:00 on 2 December on MS Teams . See https://t.co/GqOb5pp81E for course info.

[UCL MBPhD @UCL_MBPhD]

Discussion points:
📌 value of registry data from 35 European sites
📌 tricky to differentiate between COVID Sx vs cancer progression Sx?
📌 control group (patients with cancer without COVID) would help interpretation
📌 in practice, Rx adjustments depend on the clinical picture

[UCL MBPhD @UCL_MBPhD]

#JournalClub @tricia_lim97 discussed Pinato et al. @TheLancetOncol https://t.co/GBUnk2u9RN. In ~2.8k patients with cancer, post COVID-19 sequelae associated with worse survival outcomes, however dose and regimen adjustments did not.

[UCL MBPhD @UCL_MBPhD]

Fantastic start to @UCL_MBPhD Journal Club: @Jane_Ganesh presents @NEJM paper “Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel”. 3rd dose prevents infection and may reduce severe disease. Thank you Dr Amit Huppert, lead author joining from @TelAvivUni !

[UCL MBPhD @UCL_MBPhD]

Congrats to #MBPhD student @tbkwatkins + colleagues for their publication in Nature "Using DNA sequencing data to quantify T cell fraction and therapy response”
@BobbyBentham @kevlitchfield @tbkwatkins @limemilia @NickyMcGranahan @TheCrick @uclcancer

https://t.co/bNFoa1Uogx

[Callum Nattress @CallumNattress]

Excited to finally be at the first in-person conference of my PhD (and present my first poster on γδ T cells for the treatment of patient-derived colorectal cancer organoids!) @UCL_MBPhD @CRUKCOLcentre @uclcancer https://t.co/TiPs4h2QED

[UCL MBPhD @UCL_MBPhD]

Congratulations @MarcusGhosh! 🎉🎉🎉

[Marcus Ghosh @MarcusGhosh]

After 10 years @ucl I'm overjoyed to graduate from the @UCL_MBPhD programme!

Thanks to @uclmedsci @ClinProfSkills @uclcdb and @realRihellab for the memories!

[UCL MBPhD @UCL_MBPhD]

Congratulations to #MBPhD students @RyanWee and @DomGiles and @UCLMS alumnus Ernest Soh on their recent article in @ClinicalTeacher!

Title: 'Teaching data science to medical trainees'

@enherts @UCL_IHI

https://t.co/NWl8riG0A1

[UCL MBPhD @UCL_MBPhD]

Congratulations @oliverdevine - an amazing achievement! 🎉

[UCL MBPhD @UCL_MBPhD]

Congratulations to #MBPhD student @dotalawode and colleagues on their recent review in @JInternMed!

Title: 'Transitioning from cerebrospinal fluid to blood tests to facilitate diagnosis and disease monitoring in Alzheimer’s disease'

@UkdriL @UKDRI @drcionucl @UCLIoN

[JIM - Journal of Internal Medicine @JInternMed]

New review from @UKDRI fluid biomarker lab (@UkdriL) about transitioning from CSF to blood tests for #Alzheimers disease:

https://t.co/Y5UHp4rdoU

@dotalawode
@AshviniKeshavan
@NicholasAshton
@ajh1269 @jmschott
@TommyKakari
@AnniinaSnellman
@tautangle
@joelsimren

[UCL MBPhD @UCL_MBPhD]

Congratulations to #MBPhD student @VirenPandya14 and @RickiePatani on their review published in Ageing Research Reviews!

Title: Region-specific vulnerability in neurodegeneration: lessons from normal ageing

@PataniLab @UCL_QS_CNMD @UCLIoN @TheCrick

https://t.co/IvJ1aqTPdN

[PataniLab @PataniLab]

Check out our latest review on Region-specific vulnerability in neurodegeneration: lessons from norma... https://t.co/8edv83S836 Well done Viren Pandya @Patanilab @ELSneuroscience @UCLIoN @TheCrick @The_MRC @mndassoc #DrivingMNDresearch @age_uk

[UCL MBPhD @UCL_MBPhD]

Thank you to Professor Rafael Badenes for joining the @UCL_MBPhD Journal Club as our guest expert this week! @UV_EG @medicina_uv

[Rafa Badenes @BadenesR]

👨🏻‍🎓👩‍🎓Great pleasure join University College London @ucl MBPhD Journal Club. Thanks for choosing our manuscript 🧠. Thanks for inviting me 🙏🏻. @uclnews @WesElyMD @LancetRespirMed #knowledgesharing #StrongerTogether @anestesiavalen @GVAclinic @medicina_uv @incliva_iis

[UCL MBPhD @UCL_MBPhD]

Congratulations to #MBPhD student @tbkwatkins and colleagues on their #preprint in @biorxivpreprint!

Title: 'Whole-genome doubling-aware copy number phylogenies for cancer evolution with MEDICC2'

@BIMSB_MDC @HumboldtUni @SwantonLab @CRUKLungCentre @uclcancer @FU_Berlin @DKFZ

[UCL MBPhD @UCL_MBPhD]

Congratulations to #MBPhD student @sam_ereira and colleagues on their recent @SciReports article!

Title: 'Overcoming Pavlovian bias in semantic space'

@MPC_CompPsych @WCHN_UCL @Sorbonne_Univ_ @karolinskainst @DeepMind

https://t.co/WA9yvXskZC

[Sam Ereira @sam_ereira]

I'm delighted to share:

Overcoming Pavlovian bias in semantic space

https://t.co/AP7A5cGFZE

It's the first project I started and the last one I finished during my PhD. It never found a home in my thesis.

The results aren't pretty, but I hope someone finds them helpful one day

[UCL MBPhD @UCL_MBPhD]

The @UCL_MBPhD programme application deadline for 2021 and 2022 entry is next Wednesday 17 February!

Further information can be found at the following link: https://t.co/XMClz4Fnlt

[UCL MBPhD @UCL_MBPhD]

Another paper from one of our @UCL_MBPhD alumni!

Congratulations to @DemisKia and colleagues on their paper in @JAMANeuro!

https://t.co/bBcuGFnxk6

@UCLIoN @School_Pharmacy @CUmedicengage @UMU @RoyalVetCollege @RSofPharmacy @KFSHRC_Research @drcionucl @pdgenetics

[Catherine Storm @storm_catherine]

Identification of Candidate Parkinson Disease Genes Using Genome-Wide Association Study, Expression, and Epigenetic Data Sets https://t.co/J1yumlil6d @UCL_MBPhD @UCLIoN

[UCL MBPhD @UCL_MBPhD]

https://t.co/mnwmKFCutb

@SwantonLab @TheCrick @CRUKLungCentre @uclcancer @royalmarsdenNHS @DTU_HealthTech @SungkyunkwanUni @WeillCornell @sloan_kettering @TurajlicLab

[UCL MBPhD @UCL_MBPhD]

Congratulations to all authors of this recent paper in @CellCellPress, including #MBPhD students @dhruva_biswas and @tbkwatkins and #MBPhD alumnus @CharlesSwanton!

Title: 'Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition'

[Cell @CellCellPress]

New Article now online: Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition https://t.co/XYwZ7biPJe