Volynski Lab

Our lab is interested in synaptic transmission and cellular mechanisms of neurological disorders.

[Volynski Lab @VolynskiLab_UCL]

Our paper on the imaging of synchronous and asynchronous release in glutamatergic synapses is now published: https://t.co/ICpJbNseQt. Using SF-iGLuSnFR imaging, we find a universal relationship between the timing and the overall efficacy of neurotransmitter release.

[Volynski Lab @VolynskiLab_UCL]

Check this out. Our collaborative paper with Shyam Krishnakumar’s lab at Yale is now published (https://t.co/b7EUby2NPM). Using a single vesicle fusion assay, we identify minimal protein machinery sufficient to account for various modes of calcium-triggered vesicle fusion.

[Volynski Lab @VolynskiLab_UCL]

Our collaborative manuscript with Shyam Krishnakumar’s lab at Yale just posted on bioRxiv (https://t.co/VB5j1UdQZj). Using a single vesicle fusion assay, we identify minimal protein machinery mediating synchronous and asynchronous SV exocytosis and short-term synaptic plasticity.

[Volynski Lab @VolynskiLab_UCL]

Exciting News! Our paper on computational modelling of evoked vesicular release has now been published. Explore how our model bridges molecular biochemistry with physiology, advancing our understanding of calcium-activated neurotransmitter release: https://t.co/njOOEHrhA2.

[Lydia Teboul @LydiaTeboul]

We're recruiting a Senior Molecular Biologist for the Molecular and Cellular Biology team at the Mary Lyon Centre, MRC Harwell.

#CRISPR, #PCR, #nanopore sequencing, gene expression studies, and more.

https://t.co/KSZZefMLUc

Please RT!

[Volynski Lab @VolynskiLab_UCL]

Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery https://t.co/DG1Ge6Z8Rb

[Volynski Lab @VolynskiLab_UCL]

If you are interested and have PhD in Biochemistry, Biophysics or Neuroscience, please apply at https://t.co/sdwSKIwtM9
or https://t.co/qvKRG46OHD

[Volynski Lab @VolynskiLab_UCL]

Post-doc positions are open in Nobel Laureate Prof. Rothman and Prof. Volynski laboratories at UCL. Research involves imaging the phosphoinositide cycle and liquid-liquid phase separation in presynaptic terminals in relation to the regulation of neurotransmitter release.

[DANDRITE @dandrite]

In memory of our dear colleague and friend Marco Capogna, professor of Neurobiology and DANDRITE affiliated researcher.
His contribution to the neuroscience community has been numerous and very important. He will always stay in our thoughts and research
https://t.co/lR6Lno1oeg

[Lignani Lab @LignaniLab_UCL]

📢 Very happy to share our paper just published in @ScienceMagazine in collaboration with @Newrotrash and led by the fabulous @sophieqyc_q! Activity-dependent Gene Therapy for Neurological Diseases #epilepsy #genetherapy @UCLIoN @EpilepsyRUK @The_MRC https://t.co/DZYIH4WHtP

[Ed Boyden @eboyden3]

Just published in @natBME: expansion revealing (ExR), a 20x #expansionmicroscopy method that evenly separates proteins from each other for better antibody labeling, and nanoprecise imaging, on ordinary microscopes. Link to PDF: https://t.co/DiOfcDtMa6

[Neurotar @Neurotar_team]

Novel graphene arrays aid epilepsy research: Rathore & colleagues @LabWykes @VolynskiLab_UCL combine wide-field imaging with simultaneous ephys recordings using gSGFET arrays to study epileptic seizures in #awakemice. Add to your #FENS2022 to-do list, poster S04-144

[Thiemo Fetzer 🇪🇺🇺🇦 - same handle elsewhere @fetzert]

And here it is -- communication from @ERC_Research to UK-based #ERC starting grant grantees... UK awardees will have two months time to move their grant to the EU proper, otherwise they will lose their STG. Thank you #Brexit #BrexitReality.

[Bewersdorf Lab @bewersdorflab]

Introducing #panExM-t: a protocol where 🧠 tissue is expanded ✨24x✨, pan-stained with NHS ester, and immunolabeled.
Now you can see everything in the brain, even synaptic densities 👇. High potential for #connectomics!
bioRxiv: https://t.co/Okl0yxnftw

[Juan Burrone Lab @jbneuro]

Thrilled to see this work finally out in @SFNJournals #JNeurosci – study led by @VicGSB and @markrigbu. Beautiful work characterising GEVIs for measuring AP waveform in neurons and imaging APs along axons. See thread by @markrigbu for more info. @dev_neuro @MRC_CNDD @KingsIoPPN

[Dimitri Kullmann @Newrotrash]

Epilepsy gene therapy - 3 postdoc positions with @LignaniLab_UCL Stephanie Schorge, Matthew Walker and me. Spread the word! #1: https://t.co/hqwnlVxn0P #2: https://t.co/haabSw3hkJ #3: https://t.co/b14Y5MYvH7

[bioRxiv @biorxivpreprint]

Calcium dependence of neurotransmitter release at a high fidelity synapse https://t.co/VpLnYkWiKE #bioRxiv

[Katalin Toth @mossy_fibers]

We are hiring! @NeuroNaud and I are looking for a Ph.D. student and a postdoc to explore how neurons integrate synaptic signals and networks code information in the hippocampus during memory formation. Join our collaborative team!

[Daniel Choquet @daniel_choquet1]

Check our new paper just out today!

https://t.co/vfF2kdOubl

[Volynski Lab @VolynskiLab_UCL]

Check this out. Our new manuscript just posted on bioRxiv https://t.co/vdA5yqFKlj. Using SF-iGLuSnFR, we image quantal glutamate release with ~75 nm spatial and 4 ms temporal resolution and find a universal relationship between probability and synchronicity of vesicular release.