Weiser Lab @ NYU Langone Health

We study the molecular basis for host-pathogen interactions in the respiratory tract.

Twitter run by lab members. Likes/RTs are not endorsements.

[Communications Biology @CommsBio]

Profiling of pneumococcal population structure during infection reveals an unappreciated role of bacteriocins in driving the development of pneumonia by facilitating the release of inflammatory mediators

https://t.co/RnHSLwAugP

[Surya Dev Aggarwal @suryad26]

Excited to share our latest work studying pneumococcal pneumonia. We found that pneumococcal population structures undergo massive changes within the lung. This bacteriocin-mediated turnover of the population "promotes" pneumococcal pneumonia
https://t.co/eAOhtMJ7Hv

[Kristen Lokken-Toyli @LokkenToyli]

🚨Excited to share our new study below!🚨

1/7: Childhood mortality from bacterial respiratory & enteric pathogens remains a global concern. But what compromises infants' ability to fight infections? Our study delves into the immune deficiencies intrinsic to early age.

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

@dr_karthik87 Thank you!

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Why are infants susceptible to invasive pneumococcal diseases? Excited to share our latest work led by @LokkenToyli which explores this question and elucidates the age-dependent mechanisms that drive pneumococcal spread from the mucosa. @PLOSPathogens
https://t.co/98o6PyLWsf

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

@DavisLabJHU @IsbergRalph @andrewpekosz @sabraklein1998 That’s excellent news! Many congratulations 🎉🎊

[Jan-Willem Veening @JWVeening]

I’m biased, but this is such a cool paper and very happy that it’s now published @NatureComms 😀Congratulations to Anne-Stéphanie @vrrenske @suryad26 @WeiserLabNYU @LalouxLab @santosmoreno_j @YSchaerli! https://t.co/F1uh3Kfgsl

[Jan-Willem Veening @JWVeening]

Is phenotypic variation functional? Stoked about our latest preprint spearheaded by the amazing Anne-Stephanie @DMF_UNIL @unil in collaboration with a fantastic team of people @vrrenske @suryad26 @santosmoreno_j @LalouxLab @YSchaerli @WeiserLabNYU https://t.co/blwNxbQ3xg

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Congratulations to our newly minted PhD - Dr. Bee (@cwb315) did a fantastic job showcasing his research in the lab over the past 6 years! Well done 🎉🎊🍾

[Payal Yokota @PayalYokota]

Excited to see Gavyn @cwb315 from @WeiserLabNYU @nyulangone defend his thesis defense. starting now! Brilliant and touching intro from Jeff! here we go!

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Happy to share our latest work from @cwb315 that was published in @ImmunityCP earlier today!! Here is a tweetorial summarizing the major findings from this work.

[Gavyn Bee @cwb315]

Feels surreal but here it goes! Elated to share that my primary research from @WeiserLabNYU @nyugrossman @nyulangone is now out at @ImmunityCP! Tweetorial ahead! 1/n 🧵

https://t.co/Bg6SosK5iN

[Cell Host & Microbe @cellhostmicrobe]

A selfish bacteriocin dictates pneumococcal domination:Trappetti/Paton discuss @suryad26 @WeiserLabNYU work on population dynamics of S.pneumoniae colonization. Bacteriocin promotes survival of lineages, providing population bottleneck & limiting diversity https://t.co/URlqS3oxJG

[Cell Host & Microbe @cellhostmicrobe]

A selfish program reduces S. pneumoniae diversity. Intra-strain competition upon #Spneumoniae colonization causes loss of clonal diversity. Bacteriocins induced by BlpC led to predation of kin & tightening of population bottlenecks @suryad26 @WeiserLabNYU https://t.co/SRB9EPSFpL

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

https://t.co/zOLX7G4S5m

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Excited to share our latest from @suryad26, now on @biorxiv! We describe the unexpected role of BlpC in driving intra-strain competitive success, with physiological consequences on ecology of the colonizing strain and importantly, transmission to new hosts! Tweetorial below.

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Excited to share that this story by @suryad26 is now out at @cellhostmicrobe! Check it out, and tweetorial below!

https://t.co/JJ6ITHJpJj

[Surya Dev Aggarwal @suryad26]

Pleased to share some of our latest work available online now in @cellhostmicrobe. In this work, we discovered that quorum sensing induced bacteriocins mediate intra-strain competition in pneumococcus during colonization and transmission.
https://t.co/wA8l9ZTMNz

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Congratulations to graduate student Sheya @ma_sheya for passing her qualifying examination and becoming a PhD candidate. Looking forward to all the discoveries she’ll make in the lab.

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

Excited to share our latest from @suryad26, now on @biorxiv! We describe the unexpected role of BlpC in driving intra-strain competitive success, with physiological consequences on ecology of the colonizing strain and importantly, transmission to new hosts! Tweetorial below.

[Surya Dev Aggarwal @suryad26]

Happy to share this manuscript where we study the population dynamics of pneumococcus during colonization and transmission. We used chromosomal barcoding to examine how the population structure of pneumococcus changes following infection. (1/n)

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

We also welcomed our new tech Lucas Zhu who is joining us after graduating from Haverford College! Can’t wait to see all the cool science you do.

[Weiser Lab @ NYU Langone Health @WeiserLabNYU]

We celebrated our lab tech, Annie Abruzzo’s last day with an ice cream party. Good luck to Annie as she starts med school next month!