@QldBrainInst@AIBNatUQ Great collab with UQ virologists Dr Slonchak and Prof Khromykh ! Our work also shows beautiful multiciliation of the choroid plexus, defects in this process and CP polarity in DS, and the important role of the CP in facilitating virus infection of the brain. Well done Mo Shaker!
University of Queensland researchers have found a way to reverse a cellular process triggered by COVID-19 that contributes to premature ageing of the brain 🧠
Read more: https://t.co/bMalGfow7S
@AIBNatUQ@JulioAguado_PhD@Wolvejong
A study in @NatureAging shows that SARS-CoV-2 induces senescence in human brain organoids and in the brains of infected mice and humans and demonstrates the therapeutic potential of senolytic therapy in protection against COVID-19-induced brain aging. https://t.co/6F8uFkpsyS
Online now! Aguado et al., show SARS-CoV-2 induces senescence in human brain organoids and in the brains of COVID-19 infected mice and human; demonstrating the potential of senolytic therapy in protection against COVID-19-induced brain aging. https://t.co/68LcWwG4hN
‼️We found that #senolytic therapy alleviates human brain #aging and mitigates #SARSCoV2 neurological adverse effects.
Grateful to all our collaborators and to share this with you all! 🧠🔬
#covid#Senescence#Organoids
Find out more here @NatureAging 👇
https://t.co/j4cUrtxRmQ
@JulioAguado_PhD@NatureAging Congrats Julio! And thanks to all our national and international collaborators. Combining human cerebral organoid and mouse models to accelerate the pre-clinical screening of senolytic therapeutics ( for long covid in this case). Privilege to lead such a talented team.
@JulioAguado_PhD@UQ_News@harvardmed@UniFreiburg@AIBNatUQ Slowing brain ageing and treating long COVID pathology with senolytics may be possible! Leading a team that addresses global health challenges with human brain organoid models at AIBN is a privilege. Great work Julio! Big shoutout to you + our UQ and international collaborators.
@billshortenmp As an atheist scientist listening to a prime minister praising an imaginary entity for not inheriting or acquiring particular gene variants is a sad state of affairs, but expected of Hillsong. Disrespecting people with disabilities and underfunding the NDIS is unacceptable.
@MsDovic Cathy Franklin at the mater here in Brisbane is the expert in Australia IMO. We have made iPSC from fast regression DS individuals to study this with her, but grant and NHMRC synergy grant with leading DS researchers was not funded last round. Dm me if you can’t contact her
@Kasparov63 Can nato drive cruise missile launchers 1km into Ukraine, film handover to Ukraine, and then let them push the launch button? No direct nato forces involved, hard to stop by dictator Putin ,and would take out those parked lines of tanks in no time without triggering art 5 or www3
How do you study the #brain at the cell level, when you can't get inside it? You build your own brain in a dish of course! Listen to AIBN's Prof Ernst Wolvetang @Wolvejong discus how he uses this cutting-edge research to understand how brains are made https://t.co/FpCYqHF4jy
How do you study the #brain when you can't get inside to see it in action? You build one in a dish! @AIBNatUQ's Professor Ernst Wolvetang describes how he's using cutting-edge research to understand how brains are made. @Wolvejong
https://t.co/iwRA2nPvjf
#AGreyMatter#Podcast