Huibin Yu

Postdoc fellow at Bernard Moss Lab @NIH, Former Ph.D. @RothenburgLab @UCDavis, #Poxviruses, #Mpox, Structural and computational biology, Nanoparticle vaccine.

[Huibin Yu @YuHuibin]

Our latest research reveals how poxvirus antigens whose immunogenicity is restricted by fusion suppressors can be strategically re-exposed to elicit specific antibody responses. Like an iceberg splitting apart, disrupting this inhibitory interaction illuminates immune responses

[Huibin Yu @YuHuibin]

Quick links:
• Paper (free view-only full text): https://t.co/cM5RLaYAU9
• Journal page: https://t.co/5I4GwRUgPS
• "Story behind the paper" blog by Bernie: https://t.co/RrRt9DJpUM
• Nature Microbiology X post: https://t.co/NZkZNjy8KT

[Nature Microbiology @NatureMicrobiol]

Immunogenicity of poxvirus A16/G9 entry–fusion subcomplex and its restriction by A56/K2 protein informs vaccine design https://t.co/61LkGzM2nh #MicroSky

[Huibin Yu @YuHuibin]

Our latest research reveals how poxvirus antigens whose immunogenicity is restricted by fusion suppressors can be strategically re-exposed to elicit specific antibody responses. Like an iceberg splitting apart, disrupting this inhibitory interaction illuminates immune responses

[Nature Microbiology @NatureMicrobiol]

Immunogenicity of poxvirus A16/G9 entry–fusion subcomplex and its restriction by A56/K2 protein informs vaccine design https://t.co/61LkGzM2nh #MicroSky

[Trends in Immunology @TrendsImmuno]

Poxvirus structural biology for application to vaccine design https://t.co/oroCI63Que #immunology

[Jacob Yount @YountLabOSU]

🚨🚨 Our latest paper shows that IFITM3 deficiency lowers the minimum virus dose threshold for influenza and also enhances adaptation of the virus to a new species.🦠🫁 Major implications for preventing new pandemics. 😷 First author @ParkerJDenz 👨‍🔬https://t.co/XSiH6EjQKC

[Huibin Yu @YuHuibin]

@Junnan_Fang @OhioState Congratulations, good news, brilliant futures.

[Benjamin tenOever @virusninja]

I’m pleased to announce my transition to Chair of the Department of Microbiology at NYU Grossman School of Medicine. As part of this role, we’re recruiting two junior faculty for 2025, focusing on infection biology. Learn more and apply: https://t.co/Dcf8ynAgWu

[Linna An @alchemist_an]

De novo enzyme design!!! | Amazing work from Anna, Sam @DaveJuergens and all the co-authors! Computational design of serine hydrolases https://t.co/TYrtvbhvlY

[Tedros Adhanom Ghebreyesus @DrTedros]

Today the first extraordinary meeting of the Standing Committee on Health Emergency Prevention, Preparedness and Response was convened, following my declaration yesterday of a public health emergency of international concern over the upsurge of #mpox in Africa.

The Emergency Committee is currently working on temporary recommendations, which we will issue in the coming days, to provide guidance to address the acute risk of mpox in countries affected by or at risk of the disease.

In addition, I have extended for another year the standing recommendations that I issued when I declared an end to the previous mpox global emergency last year. Those recommendations provide more general guidance to address the chronic risk of mpox globally.

My full remarks: https://t.co/fw3avdyiqI

[Jason Kindrachuk, PhD @KindrachukJason]

Latest work on #Mpox coming out from many colleagues including @arimoin @PlacideMbala @LaurensLiesenb1 @labgenpath @nicolamlow
Documented transboundary transmission of mpox between the Central African Republic and the Democratic Republic of the Congo https://t.co/rnzLztTgLW

[Africa CDC @AfricaCDC]

Today, we declare #Mpox a Public Health Emergency of Continental Security.
With 2,863 confirmed cases and 517 deaths across 13 African countries in 2024 alone, Mpox is a crisis demanding our collective action. @AfricaCDC is activating resources, partnerships, and leading coordinated and strategic responses to protect our continent. We call on global partners to join us in this fight.
Read More - https://t.co/fvUhmTiZHG

#PublicHealthEmergency #ContinentalSecurity
#GlobalSolidarity

[Huibin Yu @YuHuibin]

WHO declares mpox outbreak a global health emergency

https://t.co/v2dzzgQaaU

[Trends in Immunology @TrendsImmuno]

The August @TrendsImmunoe issue is out!! #ARID1A; #NLRC5; #SpleenInnervation & #GerminalCenters; #VAV1 & #Autoimmunity & #Inflammation; #Neuroimmune crosstalk & #Hematopoiesis; #NonNeutralizingAntibodies & #SARSCoV2 ; #Iron & #MyeloidCells & more!! https://t.co/OtOEYGsR2S

[Andreas Baumler @abaumler]

Meet the Early-Career Scientists Selected for the 2024 IAI New Voices in Microbiology Collection.

https://t.co/XnczcL3gng

[fajie yuan @duguyuan]

Toward De Novo Protein Design from Natural Language:

Propose Pinal, a 2-stage generative framework, avoiding end-to-end text-protein generation.
Design an optimal sampler to integrate both stages.
Outperform ESM3 when prompting with text. #ProteinDesign

https://t.co/f8b7vxzOQS

[nature @Nature]

The World Health Organization has updated its list of most dangerous viruses and bacteria https://t.co/HhUCBpkM0y

[Craig Wilen @WilenLab]

https://t.co/HYMr7A7adP

[Stefan Rothenburg @RothenburgLab]

Tanapox Virus and Yaba Monkey Tumor Virus K3 Orthologs Inhibit Primate Protein Kinase R in a Species-Specific Fashion https://t.co/iZTzuvJjbD #mdpiviruses via @VirusesMDPI

[nature @Nature]

A 60-year-old man in Germany has become at least the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant https://t.co/YPc2QovvBa

[Why you should have a cat @ShouldHaveCat]

he asks so politely 🥺