Craig Wilen

Physician-scientist. Dad. Husband. Associate Professor @yaleibio @yale_labmed. We study host-viral interactions #covid #norovirus @wilenlab.bsky.social

[nature @Nature]

Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.

https://t.co/5rUUgxceoE

[Sholto David @addictedtoigno1]

Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.

[Konnikova lab @LizaKonnikova]

So excited to share our new work beautifully lead by @madisonstrine where we identify new properties of early life T cells. https://t.co/2rjbvxO3ab. @YaleMed @YaleIBIO @YalePediatrics

[Hans Clevers @HansClevers]

A short write-up about the journey of our lab. Starting as T cell immunologists, we stumbled across Wnt signaling in flies and frogs. Worked on colon cancer. Then Nick Barker (left) discovered the gut stem cell and Toshi Sato invented organoids https://t.co/EzK2hhyONc

[Eytan Ruppin, MD, PhD @EytanRuppin]

🚨 Out today in Cell! @CellCellPress

Path2Space: #AI that predicts spatial transcriptomics (ST) from H&E pathology, enabling spatial biomarker discovery in #BreastCancer at scale.

📄 https://t.co/GtrmH9zIDs

🧵1/8

[Casanova Lab @casanova_lab]

1/ Thrilled to share a Perspective that summarizes 30 years of work from the many labs studying the human genetic and immunological causes of infectious diseases: https://t.co/jdgw3gOWl9

[The Sato Lab (Kei Sato) @SystemsVirology]

BREAKING🔔 Our new study is out at @biorxivpreprint. We established a novel animal model for SARS-CoV-2 infection using horseshoe bats, a natural reservoir of SARS-CoV-2-related coronaviruses in nature. Please repost🦇

https://t.co/9hS3w63h9k

[Karim Majzoub @KarimMajzoub]

HIV joining the circular RNAs Club ? Welcome ! https://t.co/rXzwLeponK

[Junjie Guo 郭俊傑 @guo_lab]

Congratulations to @SteitzLab ! 🎉🎉🎉

[Prof. Hao Wu @WuLabHarvard]

Excited to share an amazing video on the NLRP3 inflammasome pathway generated by talented Ann from the Iwasa lab @janetiwasa @Ann_HuiLiu. It shows the real cryo-EM structures of the pathway from #NLRP3, #ASC, #caspase-1, #GSDMD, #IL-1b, to #NINJ1. #cryoem @LeXiao17 Enjoy

[Maayan Levy @MaayanLevyPhD]

Excited to share our new paper in @CellCellPress with @MarcoRuella, led by @Shan_Liu_
and @PuneethGuru_. CAR T cell therapy loses effectiveness over time due to metabolic exhaustion, but we found a surprisingly simple approach to address it. 👇

https://t.co/WXN9834SbE

[Craig Wilen @WilenLab]

Congratulations to Dr. Pena-Hernandez @marioph13 on his outstanding thesis defense today! We couldn’t be more proud! Both the Wilen and Iwasaki labs will miss you. @VirusesImmunity @Yale_LabMed @YaleIBIO

[Jonathan Kagan @jkagan1]

Increasing evidence that STING has functions beyond DNA viruses. A new study reports that STING restricts influenza infection, independently of IFN. This work complements prior studies that STING prevents infection with diverse RNA viruses.
https://t.co/EhkCNfz8wj

[Yale Lab Medicine @Yale_LabMed]

New study from Wade Schulz, MD, PhD (left) & @ThomasDurantMD of @YaleMed in @clin_Chem_ADLM evaluates performance of quantum machine learning algorithm—quantum circuits w/data re-uploading (QC-REUP)—compared to classical machine learning & other QML methods https://t.co/Qu2fQUN3fs

[Estes Lab at BCM @EstesLab_BCM]

New in @JVirology: How does the human norovirus particle assemble?

Particle assembly is facilitated by VP2 acting as a molecular bridge. We also share intriguing features making pandemic HuNoV VP2 unique in structure and sequence. https://t.co/hcIC7bY3kh

[Craig Wilen @WilenLab]

Grea paper. Congrats to the Lee lab @Yale_LabMed

[Waggoner Lab @LabWaggoner]

A high-throughput screening system enabled identification of the antigen targets of T cell receptors found in many individuals
https://t.co/N8A543fvLh
@ScienceAdvances @Yale

[Elizabeth Emanuel @immunologyliz]

A nice write-up from Nature Immunology about our recent paper!

https://t.co/kEx4fIBD7N

[Charlotte Lee @cljack]

I'm trying to train Claude to read the weekly emails from my kids school and reliably summarize them and print a list of action items. It is losing its damn mind and rapidly spiraling into madness. I feel vindicated

[Nature Rev Immunol @NatRevImmunol]

On the balance of knowledge https://t.co/xKZVGNLokJ

[Caleb Lareau @CalebLareau]

⚠️ If you’re reading this, you’ve been infected* ⚠️
*~95% the human population has been infected by the Epstein-Barr Virus (EBV).

Today in @Nature with @nyeo_sherry, @EMC22381830, @RyanDhindsa @SlavePetrovski, we shed some light on what happens next.

https://t.co/Db1j4aHeFO