Joel Riley

Cell Death & Inflammation Lab, Med Uni Innsbruck @imed_tweets @villunger. Postdoc @CRUK_SI @UofGlasgow, PhD @QUBelfast 🏳️‍🌈🇬🇧🇮🇪🇪🇺🧫🔬

[Philip Dunne @DrPipDunne]

Massive congrats to @MallSid – just published in @NatureGenet

Our study defines a series of pathway-derived subtypes (PDS), which we use as the basis for identifying a previously overlooked phenotypic landscape in colorectal cancer…
https://t.co/JUE5IJqVtx

🧵👇

[Joel Riley @_JoelRiley]

@DrPipDunne Fantastic - looking forward to reading! Congrats all!

[Joel Riley @_JoelRiley]

Great to see this out! Congrats @EsmeeVringer @HeiligRosalie @cat5863 @MitosRUs and everyone else - glad I could be a part of it!

https://t.co/ddoPSUxtsL

[Cosentino Lab - Molecular Cell Biophysics @Cosentino_Lab]

First visualization of super-resolved GSDMD pores at the plasma membrane of pyroptotic cells!!! Fantastic work by Shirin @viten_skap and great collaboration with
@PiehlerLab iBiOs Osnabrück and @HummerLab
Check our preprint!
https://t.co/ixW7Se5JAT

[Joel Riley @_JoelRiley]

@Cosentino_Lab @viten_skap @PiehlerLab @HummerLab Congrats!

[Yi Fu @Yi__Fu]

Do cells care if their mitochondrial DNA is broken? Yes! Excited to share my PhD work showing that a fraction of cells with breaks in their mtDNA recover healthy mitochondria using the integrated stress response.

[Joel Riley @_JoelRiley]

Great to see this out - glad to have been part of this amazing effort. Congrats to everyone involved! https://t.co/yLiqU0JHAR

[Matteo Gentili @mgentili_]

Happy to have contributed to this work by super-talented @BingxuL and @beccajcarlson. The mistery of how STING induces autophagy and NLRP3 activation is finally solved. Landmark study for the field!

Human STING is a proton channel | Science https://t.co/IA8j8nhM9n

[Garcia Saez Lab @GarciaSaez_Lab]

Who needs something to read these holidays??? Here a link to our new review about BCL2 family matters… https://t.co/axJcYJ93xN
@CRC_1218 @Ferroptosis2306 @CECAD_ @sfb_1403 @SpringerNature

[Gabriel.Ichim @GabrielIchim1]

🚨🚨🚨New review from the Cancer Cell Death team, with @BertolinGiulia2 @crcl! 🚨🚨🚨

All you need to know about visualising and quantifying MOMP and mito membrane potential- Past and Future!
https://t.co/61aip0oaOl

[Joel Riley @_JoelRiley]

@emmamarykerr Thanks Emma!

[Joel Riley @_JoelRiley]

This project is part of a @FWF_at research group at @imed_tweets, with close collaboration between us, @LabiLab5, @Francesca_Fin_ and @villunger

[Joel Riley @_JoelRiley]

🚨 We’re hiring! 🚨

We are looking for a motivated PhD student to come work on our exciting project trying to understand the early stages of B cell cancer development.

If 🧫🧬🔬 (and ⛷️⛰️) excites you, this could be the project for you!

DM or email for more info - please RT!

[Villunger Lab @villunger]

A new episode of „Death in the Alps“ is coming. All about cell death signalling in health and disease. Book 07-11th of January 2024 in your calendar and express your interest by emailing to [email protected] so we can keep you posted! Please RT

[Joel Riley @_JoelRiley]

Exciting times ahead! 🎉

[Joel Riley @_JoelRiley]

@DrPipDunne @CRUK_BI Fantastic news - congrats!!!

[AnnaKoessinger @AnnaKoessinger]

Overjoyed to see my PhD paper finally out in @cddpress! #braintumour #apoptosis #neurooncology
A big thank you to everyone involved and especially @MitosRus for the support and mentoring along the way. For everyone who is interested in what we found out a short summary below:

[Joel Riley @_JoelRiley]

You can read the entire story for yourself, just published in @Dev_Cell https://t.co/rCF8X4Xpjw

[Joel Riley @_JoelRiley]

Thrilled that the latest paper from @MitosRUs lab is out today in @Dev_Cell, which can only mean one thing… a tweetorial! We wanted to figure out how sub-lethal apoptotic stress causes oncogenic DNA damage… 🧵

https://t.co/rCF8X4Xpjw

[Joel Riley @_JoelRiley]

Tl;dr… Sub-lethal apoptotic stress causes oncogenic DNA damage through mitochondrial dysfunction. This dysfunction causes permeabilisation of some mitos via fission and BAX accumulation.