Alejandro Montesa

Biotecnologia

Zaragoza

[Alejandro Montesa @_mxntesv_]

Quiero viajar el mundo contigo de compañía 🤍🥴 MT

[Alejandro Montesa @_mxntesv_]

@compchemm Does the web server use v2??

[Alejandro Montesa @_mxntesv_]

@MolBioMike @biocheMichael For me Bioemu have never worked… compares to my own MD simulations which is indeed my field, really weird and for sure never visites conformations were generared tih Bioemu

[Jarrid Rector-Brooks @jarridrb]

What if AI could invent enzymes that nature hasn’t seen? 👩‍🔬🧑‍🔬

Introducing 🪩 DISCO: Diffusion for Sequence-structure CO-design

14 rounds of directed evolution and over a year of wet lab work. That's what it took to engineer an enzyme for selective C(sp³)–H insertion, one of the most challenging transformations in organic chemistry.

DISCO surpasses this with a single plate. No pre-specified catalytic residues, no template, no theozyme, no inverse folding, just joint diffusion over protein sequence and structure.

📝 Blog: https://t.co/j9Za0JigfO
📄 Paper: https://t.co/ficrYNBBrM
💻 Code: https://t.co/p81sSwoaPH

[Alejandro Montesa @_mxntesv_]

@sokrypton @MichaelLinLab @mkoeris And how do you explain AF3 working, despite they diminish the importance of MSA during the inference?

[Alejandro Montesa @_mxntesv_]

@futagui_ 🔵

[Alejandro Montesa @_mxntesv_]

@jaimitopaz19 @itsD3lay coscurro paletoide

[Alejandro Montesa @_mxntesv_]

@jaimitopaz19 que te pasa a ti

[Alejandro Montesa @_mxntesv_]

@6lagu Tusabes mucho

[Alejandro Montesa @_mxntesv_]

I like when your face is beat
But I like when your makeup off
Tight dress enticin' me
But I wanna see you take it off

Mrs 🥴🤍

[Alejandro Montesa @_mxntesv_]

@jaimitopaz19 No tratamos con fks

[Alejandro Montesa @_mxntesv_]

Contigo voy a muerte porque tu me has dado vida XV

[Alejandro Montesa @_mxntesv_]

Imaginate cuando me mira y sonríe, esa mierda si coloca 🤭🤍

[Alejandro Montesa @_mxntesv_]

@Isiporro1 Empiezas a entenderlo todo

[Alejandro Montesa @_mxntesv_]

No eres una maestra pero a mi tu me enseñaste a amar 🤍👹 #23preguntas

[Alejandro Montesa @_mxntesv_]

@lagunna9 Tu chiste favorito te lo conte yo, MVP en el basket y a fútbol te gano cuando quieras

[Alejandro Montesa @_mxntesv_]

@lagunna9 @jaimitopaz19 Maquillte la espalda, que después de este partido la llevas guapa

[Alejandro Montesa @_mxntesv_]

Lo bueno lo quiere todo el mundo y por eso te celo 🤍🤤