Peter Georgiev

Associate Principal Scientist @AstraZeneca | Previously @Harvard_Imm @HaigisLab | #Immunobiology + #Metabolism Enthusiast | Previously @Merck @BostonChildrens

[eLife - the journal @eLife]

Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis
https://t.co/oI7FHyVf0A

[Peter Georgiev @_petergeorgiev_]

Check out our preprint focusing on asparagine metabolism in the control of autoreative CD4+ T cell responses.

Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis https://t.co/xzeB6nfAmp

[bioRxiv Immunology @biorxiv_immuno]

Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis https://t.co/dFbdCYy6cZ #biorxiv_immuno

[Science in Boston @ScienceinBoston]

.@ragoninstitute's @alisoneringel has uncovered how aging impairs the immune system’s ability to fight cancer.

She showed that as the body ages, a type of immune cells called CD8+ T cells become less effective.

📝 @CIR_AACR: https://t.co/W6ngR3aUmp
📰 https://t.co/CHTE4Kn5vL

[Massimo @Rainmaker1973]

iPhone 14, iPhone 15 and iPhone 16

[Payal Yokota @PayalYokota]

Super excited for @lynchielydia talk at the inaugural I&I seminar series at @nyulangone. One of my favorite #GdTcell Rockstars, though today teaching us about diets:: TME.

[Peter Georgiev @_petergeorgiev_]

Nice little digest of our recent work with @jameshan_sj @alisoneringel @HaigisLab

Age is more than just a number in cancer immunotherapy https://t.co/8WoUk2DrDL

[ACIR @ACIR_org]

Georgiev and Han et al. recently identified age-related changes in the immune system that contribute to increased cancer progression and reduced responsiveness to immunotherapy https://t.co/ffxUBISiY1  @_petergeorgiev_  @alisoneringel @ragoninstitute

[Kiran Kurmi @kurmi_kiran]

Excited to announce I am starting as an Assistant Professor of Molecular and Cellular Pharmacology at the University of Miami Miller School of Medicine @umiamimedicine Honored to join the amazing teams @SylvesterCancer and the Frost Institute for Chemistry and Molecular Science

[James SeongJun Han, PhD @jameshan_sj]

Excited to share our manuscript outlining the impact of aging on anti-tumor CD8+ T cell response @CIR_AACR! Special thanks to my partner-in-bench @_petergeorgiev_, @alisoneringel for guidance and collaboration, Arlene and @HaigisLab for mentorship and all the co-authors!

[Peter Georgiev @_petergeorgiev_]

Thrilled to share our study on anti-tumor immunity during aging with @jameshan_sj @alisoneringel @HaigisLab. Here we demonstrate that the loss of tumor-reactive CD8+ T cells is a cardinal feature that accelerates tumor outgrowth in aged mice and promotes resistance to immune checkpoint blockade therapy. Our results suggest that by failing to consider antigen specificity, age-associated dysfunction of CD8+ T cells may be inadvertently conflated with bystander responses within the aged TME and resolve a long standing mystery as to why mice beyond a certain age are recalcitrant to immune checkpoint blockade therapy.

Age-associated contraction of tumor-specific T cells impairs antitumor immunity https://t.co/4naEa8eCd9

[Peter Georgiev @_petergeorgiev_]

Had alot of fun talking science at the KGCRF poster competition @harvardmed @HarvardImmunol @LandryCancerBio

[Peter Georgiev @_petergeorgiev_]

I think only we get this excited for EAE takedowns in the Sharpe lab! @HarvardImmunol

[Peter Georgiev @_petergeorgiev_]

Check out our collaborative Treg review now in print @jacionline. @MehdiBenamar18 @jameshan_sj @HaigisLab

Regulatory T cells in dominant immunologic tolerance - Journal of Allergy and Clinical Immunology https://t.co/It0mZHJ4UJ

[Peter Georgiev @_petergeorgiev_]

I am excited to share our collaborative regulatory T cell review between the @HaigisLab, Sharpe and Chatila laboratories now out @jacionline. I feel fortunate to have worked with @MehdiBenamar18 @jameshan_sj and a terrific mentoring team for this piece.

https://t.co/It0mZHIx5b

[Science Immunology @SciImmunology]

A new Review summarizes current challenges facing CAR T cell immunotherapy, examines #cancer cells’ metabolic adaptations, and identifies potential metabolic interventions to enhance CAR T cell efficacy. @OncoUNILCHUV @unil

Learn more: https://t.co/BVDHHLyeyb

[Judith Agudo @JudithAgudo1]

Recruiting postdocs interested in immune evasion and #breastcancer . Experience in cloning/cell engineering and in vivo mouse work are a plus! See the type of work we do😊 https://t.co/2MZMLeq101

[Peter Georgiev @_petergeorgiev_]

@stylebender basically just did this to Periera…what a fight #UFC287

[PhD_Genie @PhD_Genie]

Adjusting your paper within the word-limit

https://t.co/ZcyDyQ5sqD

[Cell Metabolism @Cell_Metabolism]

New! Online now: Age-associated remodeling of T cell immunity and metabolism https://t.co/738abCkUgA