I am excited to share this preprint of a project working with the incredible @Lab_LaBella@RokasLab and @capra_lab. See the the link below for a short twitter thread!
https://t.co/hCVIvjs8lO
Preprint Alert!
We @abin_abe@Lab_LaBella@RokasLab@capra_lab asked which evolutionary forces have influenced genomic regions associated w/ human traits?
We analyzed >900 GWASs to quantify enrichment for 14 evolutionary measures
Paper: https://t.co/9bSHbn6r56
Img: our approach
Preprint Alert!
We @abin_abe@Lab_LaBella@RokasLab@capra_lab asked which evolutionary forces have influenced genomic regions associated w/ human traits?
We analyzed >900 GWASs to quantify enrichment for 14 evolutionary measures
Paper: https://t.co/9bSHbn6r56
Img: our approach
Neat preprint from @VUMCResearch - looking in the #EHR, researchers did a drug-wide association study across all #COVID patients to see which drugs associated with lower morbidity and mortality. They saw 15 that could be further evaluated as treatments: https://t.co/aOL07IhgxC
Our paper on precison sub-phenotyping of stable kidney transplants is finally out at JAMA Network Open! Congrats and huge thanks to
@minnie_sarwal@msirota84 and Swastika Sur! https://t.co/PG3GByxDZA
International GWAS of suicide attempt (SA) finds strong SA locus, genetic independence of SA and psych dx and shared genetic overlap with risk factors (smoking, SES, sleep, risk taking) not mediated by psych dx. Incredible effort led by @NiamhAMullins and @Jay_J_Kang. Details 👇
I’m excited to share our preprint on the evolutionary architectures of human enhancer sequences. These evolutionary architectures can distinguish cool genomic, functional, and TE features in human enhancers. More work to come with @capra_lab!
https://t.co/h5IsFwrv2M
So pleased to share our latest in @NatureEcoEvo showing that Neanderthal introgression reintroduced thousands of lost ancestral variants with gene regulatory activity and that these reintroduced alleles are more tolerated than Neanderthal-derived alleles:
https://t.co/C2wIHn5XO1
Check our recent paper demonstrating a mosaic of selective pressures on loci associated with preterm birth. Great work led by @abin_abe in my group and @AbbeAtSea in the @RokasLab with help from @zg_uc and others. https://t.co/QjfVL2asf8
Excited to share our preprint on using machine learning to predict preterm birth risk from ~40,000 electronic health records from Vanderbilt and UCSF. Great collaboration lead by @abin_abe with: @msirota84, @RokasLab, @CosminABejan, @Velez_Edwards, others. https://t.co/EunlR9vajK
Excited to share our preprint on using machine learning to predict preterm birth risk from ~40,000 electronic health records from Vanderbilt and UCSF. Great collaboration lead by @abin_abe with: @msirota84, @RokasLab, @CosminABejan, @Velez_Edwards, others. https://t.co/EunlR9vajK
New preprint: Sexually Antagonistic Selection on Genetic Variation is Rare in Humans. Giant analysis led by @katjakasimatis in collaboration with Abin Abraham in Tony Capra’s lab. With @pastramimachine and @petrelharp. https://t.co/mjmZ0vvIdX