Aram Chung

Prof at Korea Univ / Co-founder & CEO of MxT Biotech

[Nature Biotechnology @NatureBiotech]

Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors https://t.co/jBXl0za5ct

[Eric Topol @EricTopol]

In cancer, activated T cells release abundant extracellular vesicles that transfer DNA to the nucleus of tumor and immune (dendritic) cells, turning tumors from cold to hot. An immunotherapy in the works. @Cancer_Cell
https://t.co/mHcahijOJC
https://t.co/oPT6d7lrFM

[Nature Reviews Bioengineering @natrevbioeng]

CAR-X cell engineering https://t.co/xE498BX1ar

[Nature Biotechnology @NatureBiotech]

A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery https://t.co/XyEMyZXf8B

[Science News @SciencNews]

Macrophage senescence is a central driver of chronic inflammation in aging and metabolic liver disease, and a tractable therapeutic target.

[Cell @CellCellPress]

In the latest issue! Hallmarks of cancer—Then and now, and beyond https://t.co/NZt79BwhDt

[Nature Biotechnology @NatureBiotech]

A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery #NBTNV https://t.co/FF2RE1A54E
https://t.co/BcHj57743P

[Eric Topol @EricTopol]

Steady progress towards engineering immune cells in the body now for refractory myeloma , with major implications for many autoimmune diseases and cancers
https://t.co/K3IksrCFlg
https://t.co/1AQ5rLuH1g

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in lipid nanoparticles for oligonucleotide delivery, here's an article covering 60 years of progress in the field
https://t.co/Uaefhm2k9j
https://t.co/ZvOnJegLJG

[Eric Topol @EricTopol]

Cell senescence and how it predisposes to cancer, no less how we may be able to modulate it. An outstanding @CellCellPress review
https://t.co/bmAXOS1Ybz

[Nan-Nan Deng @dengnannan]

Glad to share our new Nature Chemical Engineering article on new mechanisms for nanocarriers ! https://t.co/XgUITwkcAf

[Waggoner Lab @LabWaggoner]

Optimized mechanical stimulation provides a simple and effective strategy to counteract age-related bone deterioration and systemic inflammation
https://t.co/wBGkAQHuLz @NatureComms 🇨🇳

[Aging Science News @AgingBiology]

Microfluidic Mechanical Reactivation of Aged Stem Cells
https://t.co/mGDSj9mGMF

[Science Translational Medicine @ScienceTM]

By hitching a ride on the body’s own red blood cells, a new delivery platform for in vivo CAR myeloid cells can bypass immune surveillance and efficiently deliver mRNAs to splenic immune cells for cancer #immunotherapy in mice. @Westlake_Uni https://t.co/azDAQzTpNS

[Science Translational Medicine @ScienceTM]

Studies of uterus transplant recipients reveal how immune cells shape pregnancy outcomes, an amino acid cocktail enhances nanoparticle delivery of therapeutic mRNAs in mice, and more this week in #ScienceTranslationalMedicine. https://t.co/zbEAufOzk7

[CRISP_SCIENCE @ScienceCrisp]

"Safe and Efficient CRISPR Genome Editing of Primary Human T Cells Using a Droplet-Based Cell Mechanoporation Platform"
Kim YJ, Bang S, Chung AJ.
Small. 2026-02-05.
https://t.co/vk8IzvqvKC
... achieving up to a 2.35-fold higher efficiency than electroporation.

[Nature Chemical Engineering @NatChemEng]

Now online!

A post-assembly, reversible crosslinking strategy that enhances lipid nanoparticle-mediated mRNA delivery while preserving efficient intracellular release.

Link ($): https://t.co/S4acqWEOMa

Free PDF: https://t.co/rVbHAiMe7D

[Science News @SciencNews]

Eleven clinical trials that will shape medicine in 2026

[Nature Biotechnology @NatureBiotech]

Our editors pick their favorite research articles from 2025 https://t.co/36ShziKQS4

[Nature Biotechnology @NatureBiotech]

CAR-T and NK cells engineered using a non-viral circular single-stranded DNA system show effective anti-tumor function https://t.co/cVEi5pjPmj
https://t.co/DvtYRi1eOS