Soumya Bhattacharyya

Takes photos of cells and builds stuff with lipids. Tries to play the piano sometimes. Currently postdoc @CRGenomica. Graduate from @TPucadyil Lab.

[Pombo-GarciaLab @karina_pombo]

Excited to see out in @Nature my postdoc work! “Membrane prewetting by #condensates promotes tight junction belt formation” How do #tightjunctions form a belt in #epithelia sealing our body cavities? @Honigmann_Lab @mpicbg @BIOTEC_TUD w/ #Jülicher @mpi_pks
https://t.co/TuXF7MOy5d

[Ishier Raote @ishier_raote]

Great Viewpoint from Vivek Malhotra @JCellBiol!
COPII proteins, essential for cargo export from the ER, form not only coated small vesicles but also collars at tubule necks and phase-separate into liquid-like condensates, adapting to physiological demand.
https://t.co/RrShsulJOs

[Hiral Shah @HiralABShah]

1/n My postdoc work on the evolution of mitosis in Ichthyosporea @Dey_Gautam @dudin_o @SchwabYannick groups is out @Nature https://t.co/KqylyMVT1A Art by @nirupa_rao contrast fungal-like closed with animal-like open mitosis. Why do cells carry out mitosis in different ways?

[Eric Betzig @Eric_Betzig]

#FluorescenceFriday #cellbiology #bioart Three examples of mitochondrial remodeling by lysosomes/late endosomes actively transported along microtubules, as seen by grazing incidence structured illumination microscopy at 1-2 frames/sec. https://t.co/oKbIu8V7VQ

[Uma Swaminathan @umaswaminathan9]

Happy to share this mini-review that @TPucadyil and I wrote for Biochemical Society Transactions.

https://t.co/bdTYjSfura

[Soumya Bhattacharyya @afororange]

@PNASNews @TPucadyil @IISERPune Thank you all!

[Soumya Bhattacharyya @afororange]

Online now @PNASNews! It was fantastic to work with @TPucadyil on this. I learnt so much from him in putting this together and had a fabulous time completing my PhD in his lab @IISERPune.
https://t.co/D6sbrWp84Q

[Soumya Bhattacharyya @afororange]

@iam_Mridula @PNASNews @TPucadyil @IISERPune Thanks Mridula!

[Soumya Bhattacharyya @afororange]

@ghosharindam_92 @PNASNews @TPucadyil @IISERPune Thank you!

[Centre for Genomic Regulation (CRG) @CRGenomica]

🙌🏿 Congratulations to Vivek Malhotra on his election to the American Academy of Arts and Sciences @americanacad

Dr Malhotra, group leader of the Intracellular Compartmentation lab at #CRG, joins a distinguished collection of leaders and professionals across many fields.

[Soumya Bhattacharyya @afororange]

@MeghdutSengupta @naacl @roxanneelbaff @miladalsh @AIHannover @trr_318 @webis_de Dónde está el enlace al manuscrito?

[Meghdut Sengupta @MeghdutSengupta]

Our paper 'Analyzing the use of metaphors in news editorials for political framing' got accepted at the @naacl mains! Congratulations to all the co-authors @roxanneelbaff @miladalsh and Henning Wachsmuth. @AIHannover @trr_318 @webis_de #NLP #NLProc. See you in Mexico!

[Ishier Raote @ishier_raote]

Our biophysical model in @PNASNews! ER export of collagen driven by a mechanochemical ratchet formed by expansion-contraction of intrinsically disordered regions (IDRs) of TANGO1, and gradients of pH/HSP47. IDR “breathing” produces work with each breath.
https://t.co/J170FHpSQx

[claudio bussi @claudiobussi]

How can lysosomes, when ruptured, maintain stability allowing for repair? Glad to share @Nature https://t.co/oFysi2d1kv the function of stress granules (SG) as molecular plugs that stabilise damaged membranes @TheCrick @maxgabgut #condensates #lysosomes #TB👇Thread

[Ishier Raote @ishier_raote]

Collagen transport through inter-compartmental tunnels! Our theoretical model, led by the Pincet group @LP_ENS_, for how molecular gradients between organelles drive cargo transport through a tunnel - even without a cargo receptor.
https://t.co/NY0vq91DHI

[Himani Khurana @himanidkhurana]

Happy to share with you, our piece on how the molecular membrane fission machine - dynamin is regulated by 'gears' in its membrane binding PH-domain. @TPucadyil and I curated this brief review for Current Opinion in Cell Biology. Now online: https://t.co/1tAMlGpj7p

[Alice Ting @aliceyting]

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase period (minutes to hours) and then 1-minute APEX tagging in the destination compartment. Proteins tagged by both enzymes are enriched with streptavidin and anti-fluorescein antibody, and identified by mass spec.

We explore 4 intracellular and intercellular applications of TransitID:
- discovery of locally translated mitochondrial proteins (translated at OMM, then imported into mito matrix)
- mapping proteins whose cytoplasm-to-nucleus shuttling is dampened by stress
- discovery of proteins that transit between nucleolus & stress granules during stress & stress recovery
- analysis of proteins that traffic intercellularly bw tumor cells & macrophages

Work of amazingly talented co-first authors @WeiQinChemBio and @CheahJoleen, and collaborators Steve Carr @namude & Paul Taylor

https://t.co/yo4laOA14z

[Ewerslab @ewers_helge]

New on BioRxiv: Adhesion energy controls lipid-binding mediated endocytosis. A group effort lead by @RaluucaG with contributions from our friends @taraskalab @DimovaLab @cmatthaeus2 and Thomas Weikl @MpiciPotsdam @FUBiochemistry @FU_Berlin https://t.co/TqkThLdKqW

[Shashi Tharoor @ShashiTharoor]

1/2 Our stressed-out PhD scholars deserve a long-overdue increase in their stipends. The revision was due in 2022 after an already delayed raise in 2019. How can they meet their daily needs & undertake research amid rising inflation?
@IndiaDST
https://t.co/UnlsJwBnpS

[Reika Tei @ReikaTei]

Our work about superPLD is now published! In this paper, we describe how we can harness mammalian cell-based directed evolution to engineer a membrane editor (phospholipase D; PLD) with superior performance in mammalian cells. 1/n https://t.co/JUGXRL7RDy