Our collaborative paper is preprinted in bioRxiv: Connectivity Logic of Dendritic Spines in Cortex: Increased Inputs and Ensemble Formation https://t.co/EiuCX3X6eW
New paper from the lab. Using longitudinal ca imaging, activity-dependent tagging and optogenetics, we show that newly allocated fear engram neurons in amygdala undergo a brief period of coordinated “offline reverberation” immediately after learning.
https://t.co/ELcRXieer2
New @NatureComms paper: we found a circuit that signals trial outcomes to the prefrontal cortex—and why stress makes it harder to learn from mistakes. Thanks @DailyNeuron_ for the coverage! https://t.co/oQuJvnV95g #zuolab#stress@MaShaorong
What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan.
https://t.co/wInz2rVo8M
Cortical circuits are often thought to be specialized, but the same large-scale activity patterns can arise from different circuit architectures. In other words, different instruments can play the same tune, and the same instrument can sometimes play different tunes.
New @ScienceMagazine
Engineering the brain's astrocytes to clear amyloid plaque!
"CAR-A," in mouse model
https://t.co/u9zJGnCLUj
https://t.co/eIrrFx7iTg
アブストにある「Finally, increasing stress prior to memory recall enhanced reconsolidation, an effect that was mimicked by amygdala cell-type-specific upregulation of noradrenaline signaling.」ってのが個人的にはとても興味深いです。
Excited to share our new paper:
We uncover an LC→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala neurons during reconsolidation—plus stress/elevated noradrenergic signaling at recall can strengthen memory.
https://t.co/iKtDam3soo