Andreas Hülsmeier

Biochemist with interst in lipids, glycans, proteins and their regulation... husband and father of two
@[email protected]
@ahulsmeier.bsky.social

[Pieter Dorrestein @Pdorrestein1]

A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs). https://t.co/kZEyjh86bf... This was extrapolated to suggest that ISFs affect all experiments to this degree. A counterpoint. https://t.co/ovGKhbsq5e

[Andreas Hülsmeier @ahulsmeier]

Glycosphingolipids in neurodegeneration? 🧠 Lipids may hold the key to understanding Alzheimer's, Parkinson's, and beyond. Discover how glycosphingolipids influence neurodegeneration and explore their potential as therapeutic targets in this latest review.
https://t.co/0umP6Hc3kd

[Alba Silipo @AlbaSilipo]

#structure and #immune recognition of the LOS from #Akkermansia muciniphila challenging spectra for a challenging structure 😎 #nmr #Massspectrometry #LPS #TLR @SimoneNicolardi
@di_flaviana @MolinaroTony @MartaTiemblo @glytunes https://t.co/I61npqpNtp

[Museer A. Lone @MuseerSphinx]

Thank you @shaha_kash and @KhalifaUni UAE for the invitation. We had a great conference.

[Abdou Rachid Thiam @Rachid_Thiam]

A breakthrough from the lab! A game-changer and the dawn of a new era in membrane and organelle biophysics and biology. We've generated giant organelle vesicles #GOVs with conserved biochemical activity. @AgenceRecherche @LP_ENS_ @ENS_ULM @NatureComms
https://t.co/2NByLYeSNI

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[Ewerslab @ewers_helge]

Paper out: Gene encoded nanoparticles (GEMs) with 180 GFPs are cool tools to track in cells. GEMs reveal biophysical basis of infection, too. Using GPI-anchored nanobody receptors over 6 logs of affinity shows that adhesion energy alone explains uptake! https://t.co/cK6dZeOCed

[Museer A. Lone @MuseerSphinx]

New genes and mutations that cause childood form of ALS. Our collaborative efforts bearing fruit. Thank you @JNNP_BMJ and all the collaborators. #ALS #sphingolipids #rarediseases

[Fascinating @fasc1nate]

In 1948, Swiss pharmacologist Peter Witt embarked on a noteworthy investigation concerning the impact of drugs on spiders.

His study involved a series of experiments wherein he administered drugs to the spiders through two distinct methods: either by feeding them flies that were drugged or by providing them with a small amount of a drug dissolved in water.

To assess the effects, Witt captured photographs of the spiders' webs both before and after the administration of the drugs. The subsequent findings are presented below.

[Lipidomics.at @Ahrends15]

Lipid Space Tool is here! It is a stand-alone tool to analyze and compare lipidomes by assessing their structural differences.

More: https://t.co/sYRIK4HjAP

[Callum Ives @CallumMIves]

It’s the most wonderful #glycotime of the year! Let us (@ElisaTelisa @Ojas_Singh_) introduce you to #GlycoShape (https://t.co/kHCplnLKYv), a web platform that allows users to restore glycoproteins 3D structures (PDB, AF/RoseTTAFold or own) to their natural, functional state by adding the missing glycan structures https://t.co/vNpOx3FJN1 🧵1/8

[jake hofman @jakehofman]

Excited to announce a new paper in PNAS today!

An illusion of predictability in scientific results: Even experts confuse inferential uncertainty and outcome variability

https://t.co/wfhRN1pq9L

Joint w/ great coauthors @_szhang, @P_Heck, @MichelleNMeyer, @cfchabris & @dggoldst

[Prof. Nikolai Slavov @slavov_n]

https://t.co/XV7TUYG5f0

[Oded Rechavi @OdedRechavi]

Reviewers don't get paid, but maybe they could get tips?

[Andreas Hülsmeier @ahulsmeier]

The importance of validating antibody performance https://t.co/VIlozmucB7

[Andreas Hülsmeier @ahulsmeier]

The need of dietary products for anti-tumor immunity... https://t.co/h20r01lF5M

[Cell @CellCellPress]

Now online! Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth https://t.co/zuvPBnd6KY

[Proia Lab @ProiaLab]

Lipid structure matters in lysosomal storage disease https://t.co/fSMpZe38Nx

[Bundesministerium für Wirtschaft und Energie @BMWE_]

It's almost four weeks since the horrific terrorist attack on #Israel. A lot has happened, the public debate has become heated and confused. Find thoughts from Vice-Chancellor Robert #Habeck in the video, putting the events in context. 📣With English, Hebrew and Arabic subtitles.

[The NCFG @theNCFG]

You have heard of the periodic table of elements-
we present the Periodic Table of Monosaccharides, where we attempt to arrange the monosaccharides in a systematic table.

Published in Glycobiology: https://t.co/uRQKJYiW7R

#glycotime #glycoeducation #glycans #monosaccharides

[Andreas Hülsmeier @ahulsmeier]

A great thanks to our dedicated co-authors for their invaluable collaboration in making this story possible.

The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy - Journal of Lipid Research https://t.co/6qt6NwCuA3