Does tocilizumab lower cardiovascular risk in giant cell arteritis? New observational data presented at #ESCCongress + sim pub: target trial emulation of 1,997 pts found 2-yr MACE 6.4% vs 10.7% with methotrexate. https://t.co/bVvnLfeRv8 @alguedon
🦴 Giant cell arteritis & Clonal hematopoiesis (CH) —somatic mutations in HSCs
👥 55.1% of patients with GCA had CH
🔬 TET2 & JAK2 mutations in #GCA ➡️ Relapse & poor outcomes.
👉 Screening for CH may guide tailored therapies.
🔓https://t.co/MHoGaFDJ7S
@alguedon
Colchicine is the first anti-inflammatory drug approved for athero-CVD prevention
#CONVINCE tested colchicine in ischemic stroke🧠
The results were presented at #ESOC2024 by Peter Kelly @ESOstroke
https://t.co/DsvIR0B5m1
The primary endpoint was negative. A🧵with some thoughts
I had such a great time at the #EASCongress! Thanks to the #EASYoungFellows programme I was able to gain so many new experiences and expand my network. Hope to see you all again soon and thanks to everyone who made it such a fabulous congress! #EASCongress2024#MyEAS2024#EAS
3 papers in NEJM published simultaneously with presentations by Christie Ballantyne and Bob Rosenson at the European Atherosclerosis Society Congress in Lyon France - documenting huge reductions in remnant cholesterol after siRNA inhibition of ApoC3 and ANGTPL3
I was very honored to provide my commentary for the @BloodJournal on the very nice paper about thrombosis and VEXAS by the fantastic @emmamgroarke team !
Presented at #ERA24:
FLOW trial: In patients with type 2 diabetes and chronic kidney disease, weekly semaglutide significantly reduced risks of major kidney events, cardiovascular events, and death from any cause while slowing loss of kidney function. https://t.co/Q9DAA6mPte
The multi societal #PAD guideline in print at long last… Amazing things can happen when specialties work together, review the evidence, and put the patient at the center. Hats off to a most collaborative writing committee. @herbaronowMD@DartmthSurgHSR@schuyler_jones
1/ Published today: The updated evidence-based recommendations for managing Lower Extremity PAD, originally outlined in the 2016 Guideline, now incorporate the latest research findings to assist clinicians.
✍🏽:@heatherlgornik
📖: @CircAHA
3⃣rd edition of the 4EU+PharmacoEpi course with #PharmacoEpi students from all over Europe at @UniHeidelberg ! Great discussion on multi-database studies. Stay tuned for next edition in Jan 2025 ! @4EUplusAlliance
https://t.co/D8PQ1OwoCt
The 3rd edition of the 4EU+PharmacoEpi course has just started with 22 students from 5 EU universities ! A new extended edition supporting an integrative educational 🇪🇺 program in pharmacoepidemiology in the @4EUplusAlliance