Hi, we have published a study in @Structure_CP that you may like it! This work is the result of a fantastic collaboration between our group @IBMCP and @LlorcaLab (@CNIOStopCancer), aimed at understanding the role of the HSP90 cochaperone R2T in plants https://t.co/LX6Syus7R1 👇
The γTuRC saga goes on!
This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator.
Another tour de force led by @sernarina and Fabian Zimmermann and a fun collab with @LudersLab@IRBBarcelona.
https://t.co/0fEKmBGzQd
Thrilled to share our last work @CellRepPhysSci Revealing the molecular mechanism of an anti-tumoral compound inhibiting our favourite system, RUVBL1/2 (at 2.4 Å resolution)🔥
All-@LlorcaLab work led by @CarmenBePaper and @alopezperrote
Link below 👇
https://t.co/vbRd2iEIHy
And also... 🔥pre-print alert🔥
We take a look at our favourite system in plants🌱, the R2T complex, an HSP90 co-chaperone.
A study led by @alopezperrote (@CNIOStopCancer) and Alberto Palacios (from @AlabadiDavid's lab at @IBMCP).
Check it out 👇
https://t.co/K1JUZL9rJI
Big congratulations to our new #CNIOStopCancer PhD Dr. Natalia Cuervo Iturrioz! 🎉
👉#CNIOPhDThesis: 'Human WAC is a partner of chaperone complexes involved in the assembly and activation of mTORC1'.
Exciting times are ahead! 👏
🎓Directors: @OscarLlorcaCNIO and @sernarina.
PAPER ALERT🔥
We took a deep dive into the microtubule 🔍 using cryoEM ❄️🔬to capture the earliest steps of nucleation by the γTuRC complex. With @sernarina and @DeBritoClaudia leading the way.
Proud of our collab with the @surrey_lab at the @CRGenomica !
https://t.co/Uu3fhaiIwc
📸Hoy hemos mantenido una reunión de seguimiento del consorcio que coordina nuestra investigadora @MaiteHuarteLab, en el que participan @CNIOStopCancer y @CNB_CSIC
🔝Proyecto que busca nuevos tratamientos para el cáncer colorrectal financiado por #CaixaResearchFundlaCaixa
Just out! RUVBL1/2 strikes back, this time together with ZNHIT2, a complex involved in the maturation of PRPF8. The great @sernarina, @AnaCorpalez, Sofía Cabezudo and @alopezperrote spearheading this project. Full text link below 👇