Genome integrity maintenance during cell cycle progression: This is what we care about, this is what we study. #ReplicationStress & #DNADamage @UZH_Science
Sharing our latest work @UZH_en tracking DNA damage inheritance by Live+QIBC https://t.co/pN5Ivt8DIV. Huge congrats to @APanagopoulos_, M. Stout and all co-authors for this tour de force! Beautifully summarized by @S_J_Aitken and E. Reilly @NatureNV https://t.co/9IVexti382.
The Ly Lab @CRI_UTSW is recruiting two #postdocs to study intercellular DNA transfer. Join us to tackle fundamental questions at the intersection of genome instability, cell-cell communication, and cancer evolution. Please share! 🙏
Full posting: https://t.co/INoSPaqx95
Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7)
https://t.co/SbshGhofN0
Excited to announce: EMBO Workshop: DNA damage response in cell physiology & diseases - 12–16 Oct 2026 - in stunning
Sounio, Greece - fabulous speaker speaker lineup representing the cutting-edge of genome stability research
Abstract deadline: 17 May: https://t.co/g2WUDSYBiq
Excited to share our new Nature study! 🧬
We (@UruciSidrit et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful co-directional clashes with DNA replication machinery. This protects cells from R-loops and genome instability.
https://t.co/oVshI7n2Mt
🚨 Exciting news! Our latest study is out in Nature Communications! We reveal how specific BRCA2 mutations can hijack transcriptional programs—beyond their role in DNA repair. 🔗 https://t.co/W9gnJlkoEb #CancerResearch#BRCA2#Genomics
Our latest paper has just been published in Cell!
https://t.co/5iAl1EaGEJ
We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
📢Please spread the word📢
Several postdoc positions (wet and computational) open in the lab to work on different research lines (see thread)
We seek highly motivated candidates to join our team @CNIOStopCancer
https://t.co/FB0aq7gHfb
E-mail CV and brief motivation statement
Excited to share our latest research “DNA2 enables growth by restricting recombination-restarted replication” in @Nature defining DNA2’s essential function and elucidating links to primordial dwarfism and cancer. Thanks to the team and all collaborators! https://t.co/ngh0fabG1T
📢Deadline extended!
Our 2nd Spatial Genome Organisation Conference deadline has been extended to 25 Sep, dont miss out on joining our fantastic line up of speakers, alongside Karim, Matthias and Irene in what is set to be a fantastic meeting this October! #SGO25
Final slots ➡️https://t.co/kl9gBjkYvA
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
https://t.co/pNPOg1u3ZB
Please repost!
Deadline approaching for our 2nd Spatial Genome Organization Conference! #SGO25
🗓 31 Oct – 03 Nov 2025
📍Riviera Maya, Mexico
👨🔬 👩🔬 🧑🔬 Chairs: Matthias Altmeyer @altmeyerlab , Irene Chiolo, and Karim Mekhail @KarimMekhail
Join an international community of scientists uncovering the roles of nuclear and genome architecture in biology, development, aging, and disease.
🧭 Poster submission deadline: 01 Sept 2025
🧬 Registration deadline: 01 Sept 2025
📎 Details & registration: https://t.co/dt9YpeXkdG
We have a handful of $250 registration grants remaining! To claim, email [email protected] with your name, position title, current research topic, and an abstract for a poster presentation.
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇 (LINKS BELOW)
Another exciting research article from a member of the #RepliFate network!
The @altmeyerlab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis.
Check out their findings here: https://t.co/1uO6kmaOYM
New work from the lab: Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling @CellReports. Congratulations to first author Antonio Galarreta and to all co-authors. https://t.co/WE2QHsIs0S. #Microscopy#RNAiScreen#Condensates
Want to better understand nuclear and genome organisation in various organisms, tissues, and cell states? Join @KarimMekhail , @altmeyerlab & Irene Chiolo at the upcoming 2nd Spatial Genome Organisation Conference this October!
Talk Submission has been extended until 14th July, dont miss out! 👉https://t.co/2lwoncRDW5
#SGO25
An ingenious technique reveals how stressed cells divide to produce progeny that have different traits — a phenomenon that can initiate cancer
https://t.co/TUr266wBpL
I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @ScienceMagazine ! (link at end of 🧵)
New @Nature
An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer
https://t.co/5S2QIorb0A