Anika Singanayagam

Consultant Virologist at UKHSA.
Respiratory and enteric viruses / transmission / human challenge / public health.

[Anika Singanayagam @anikasinga]

Listen to a Lancet podcast where we discuss our @LancetMicrobe #humanchallenge paper here:

https://t.co/sO3mrGvb83

[FluTrackers.com @FluTrackers]

US - California: CDPH statement - 3rd #H5N1 confirmed human case confirmed by the CDC. + 2 more possible cases identified with CDC tests pending. All are animal contact, mild symptoms. https://t.co/tYjbx7kZVz h/t Commonground

[Anika Singanayagam @anikasinga]

@jbloom_lab What is the effect of S323 on HA stability? Looks suspiciously close to the fusion peptide and several other mutations well described to affect stability.

[Helen Branswell 🇨🇦 @HelenBranswell]

Doses of an experimental #Marburg vaccine — designed at the @NIH's Vaccine Research Center & being developed by @sabinvaccine — arrived in Rwanda on Saturday where a clinical trial will soon get underway. Photo: Sabin Institute https://t.co/QblwMkTDF1

[Anika Singanayagam @anikasinga]

https://t.co/NXWAWJD9Fi

[Anika Singanayagam @anikasinga]

https://t.co/DxNkzrHOjU

[Options2024 @options2024]

@mvankerkhove of @WHO urging for evidence driven policy, equitable access to safe and effective vaccines, building Pandemic Influenza Preparedness (PIP) strategy, and platforms to facilitate sharing of key reagents

[The Pathologist @pathologistmag]

Do we need more women in #pathology mentoring and leadership? Ann Gronowski believes we do, and here’s why 💭 https://t.co/PmUnG1TbuI

[Prof. Akiko Iwasaki @VirusesImmunity]

An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/)
https://t.co/Z15xiyxCLS

[Anika Singanayagam @anikasinga]

Nice article

[The Pathologist @pathologistmag]

Are diagnostics up to scratch in tackling #polio and other #enteroviruses?

Read more: https://t.co/2JBDAa3dsC
#InfectiousDisease #DiagnosticsDevelopment #VirusResearch

[Anika Singanayagam @anikasinga]

@jbloom_lab Same glycosylation site as was lost in the two 2012 H5N1 ferret transmission experiments

[Anika Singanayagam @anikasinga]

Amazing, quick work! Would like to hear what is happening in NA/2SBS also. A160T restores a glycosylation site that could affect HA:NA balance e.g. https://t.co/HLDjg7rjsA

[Bloom Lab @jbloom_lab]

Here is analysis of HA mutations in H5 influenza case in Missouri resident without known contact w animals or raw milk.

TLDR: there is one HA mutation that strongly affects antigenicity, and another that merits some further study.

[Anika Singanayagam @anikasinga]

Picked up via routine national influenza surveillance 💪

[CDC Flu @CDCFlu]

CDC confirmed a human case of H5 bird flu in Missouri in a person who has fully recovered. This is the 14th case in the United States in 2024. An investigation into the potential exposure is ongoing, but the public risk assessment remains low at this time. Read more: https://t.co/yzwencYOZx

[Imperial Medicine @ImperialMed]

Why are some people volunteering to be infected with diseases?

Dr @anikasinga from @ImperialInfect shares preliminary insights and findings on the SARS-CoV-2 human challenge study with @BBCNews

#COVID19
https://t.co/h2lkl5USNy

[CIDRAP @CIDRAP]

Clinicians detail H5N1 infections in 2 Michigan farm workers

One patient had conjunctivitis in one eye, and the other had longer lasting flulike symptoms.

https://t.co/RZ2tDHYJML

[Medical Schools Council @ukmedschools]

MSC has published its findings on the 2023 clinical academic survey, revealing an ageing workforce and continuing gender and ethnic imbalances in clinical academia.

Press release: https://t.co/1937d0UN4R
Interactive tool: https://t.co/RoV1VpfSKN

[Helen Branswell 🇨🇦 @HelenBranswell]

3rd US #H5N1 #birdflu case, this one with respiratory symptoms. Farm worker in Michigan who wasn't wearing PPE. Said to be recovering. https://t.co/NdS5cBRyFg

[Anika Singanayagam @anikasinga]

Agree with all of this - great article in @NatureMedicine - "Why diversity is needed at every level of clinical trials, from participants to leaders"

https://t.co/ZoZC9PNTRJ

[Secretary Tom Vilsack @SecVilsack]

To further protect the U.S. livestock industry from the threat posed by highly pathogenic H5N1 avian influenza, @USDA is sharing a number of actions that we are taking with our federal partners to help us get ahead of this disease and limit its spread. https://t.co/c1t2TdfTyE

[Anika Singanayagam @anikasinga]

https://t.co/G3ABploIJC