Aditya Pimplaskar

Bioinformatics/psychiatric genetics PhD candidate @CompMedUCLA | @ucla CompBio+Math alum | Here mainly for science + NBA twitter & geography memes. (he/him)

[Aditya Pimplaskar @apimplaskar]

Excited to see our work in AJHG! Thank you to our amazing co-authors, UCLA Institute for Precision Health, UCLA CTSI, and our collaborators for the support with this work. Above all, we are grateful to the patients and ATLAS biobank participants at @UCLAHealth.

[AJHG @AJHGNews]

🧬New today!
📄Inclusion bias affects common variant discovery and replication in a health-system linked biobank
🧑‍🤝‍🧑 @loldeloo @apimplaskar @bpasaniuc & co

https://t.co/tcU7jJjwzt

[Cell Genomics @CellGenomics]

FastGxC: Fast and powerful context-specific eQTL mapping in bulk and single-cell data https://t.co/bwVzqR1N7R

[ESPN @espn]

UCLA WINS ITS FIRST NCAA NATIONAL TITLE IN PROGRAM HISTORY 🏆

[Lucas Bandarkar @LucasBandarkar]

Interpretability has not kept up with scaling LLMs at all, especially for *knowledge*. But here's a wild idea:
using cross-lingual knowledge inconsistency (typically seen as a "bug") as a tool for dissecting where knowledge lives
🧵1/4 https://t.co/9iLZ3DExOH @GoogleResearch

[Saarang Panchavati @saarang_p]

New preprint! We mapped thalamocortical dynamics in human focal epilepsy using SEEG. We found distinct spectral and connectivity based signature that could be direct targets for neurostimulation.

With @UCLAMCH and @uclamii

https://t.co/MG7Lr7TAnm

[Daniel Israel @danielmisrael]

"An hour of planning can save you 10 hours of doing."

✨📝 Planned Diffusion 📝 ✨ makes a plan before parallel dLLM generation.
Planned Diffusion runs 1.2-1.8× faster than autoregressive and an order of magnitude faster than diffusion, while staying within 0.9–5% AR quality.

[Aditya Pimplaskar @apimplaskar]

Would love to connect/discuss projects w/ folks interested in EHR-based phenotyping methods for genetic studies, psychiatric genetics, and perinatal health!
#ASHG25

[Aditya Pimplaskar @apimplaskar]

Excited to visit Boston for #ASHG25. I’ll be presenting our work on the effects of recruitment bias in biobank studies on Friday (10/17) @ board 1126 — please drop by and say hi!

[Aditya Pimplaskar @apimplaskar]

@Hyunkyungkim_ See you in Boston! Excited to hear about your work

[Daniel Israel @danielmisrael]

🔦Adaptive Parallel Decoding (APD) has been accepted as a spotlight paper at @NeurIPSConf ! I thank my collaborators, reviewers, and program organizers for this honor.

A thread for those interested 🧵 (1/n)

[Elaine Huang @elainee_huang]

Our work on genetic variants that affect RNA stability is out in @NatureGenet! We present the RNAtracker computational pipeline, which can distinguish between transcriptionally- vs. stability-mediated regulation of gene abundance. https://t.co/zwAH2N8ZxJ (1/n)

[Aditya Pimplaskar @apimplaskar]

@humzalikhan @StanfordDaily linking to the dictionary definition of luddite is such a humza thing to do -- this could never have been written by an LLM (i also love em dashes)

[AJHG @AJHGNews]

📣New from @bpasaniuc & co
📄Exploring #depression treatment response by using #polygenic risk scoring across diverse populations
https://t.co/RLtLoiaev9

[Daniel Israel @danielmisrael]

“That’s one small [MASK] for [MASK], a giant [MASK] for mankind.” – [MASK] Armstrong

Can autoregressive models predict the next [MASK]? It turns out yes, and quite easily…
Introducing MARIA (Masked and Autoregressive Infilling Architecture)
https://t.co/h8H9l5pOnK

[Chongyuan Luo @chongyuanluo]

Does ambient RNA/DNA confound the genotype-based demultiplex of 10x Multi-ome data? Terence Li @terencewtli, a bioinfo grad student in Noah Zaitlen lab and my lab investigated precisely this question and provided practical recommendations.

[bioRxiv Bioinfo @biorxiv_bioinfo]

The impact of ambient contamination on demultiplexing methods for single-nucleus multiome experiments https://t.co/RriiGPC0a7 #biorxiv_bioinfo

[Molecular Cell @MolecularCell]

Online Now: Single-cell stimulus-response gene expression trajectories reveal the stimulus specificities of dynamic responses by single macrophages https://t.co/mkO9PUPpwv

[AJHG @AJHGNews]

📢Online now!
📰Splicing-specific transcriptome-wide association uncovers genetic mechanisms for #schizophrenia
🧑‍🤝‍🧑@gracexiao99 @bpasaniuc & colleagues
https://t.co/TPEh5ow37x

[Saarang Panchavati @saarang_p]

Excited to share that our paper: "Uncovering spatiotemporal dynamics of the corticothalamic network at ictal onset" is out in Epilepsia!

with Hiroki Nariai, Atsuro Daida, Shingo Oana, @BillSpeier, @uclachildneuro, et. al

https://t.co/tykx2YtyKA

(1/4)

[Aditya Pimplaskar @apimplaskar]

I’ve been advised to put up a poll

[Aditya Pimplaskar @apimplaskar]

Settle a debate for me (and some friends): is a tent flap considered a door?