The Arany lab

We are the Arany lab at University of Pennsylvania. We love metabolism !

[Cell Metabolism @Cell_Metabolism]

New! Online now: Quantification of nutrient fluxes during acute exercise in mice https://t.co/9CkxFDgkI8

[The Arany lab @AranyLab]

Reporting with pride: (1) our star Jessie Axsom is now Dr.! (2) her paper is out @Cell_Metabolism: unbelievably comprehensive quantification of fuel fluxes in #exercise mice - lots of surprises. #MoTrPAC: take note. w/Rabinowitz lab. Free link 50days: https://t.co/cVXPQZwL7b

[The Arany lab @AranyLab]

Fantastic brief historical overview of mechanism behind #preeclampsia from brilliant friend @ananthmsn34 in @jclinicalinvest : https://t.co/svLN8tTh3r

[Cell @CellCellPress]

From our newest anniversary focus issue on #Metabolism!

"Human cardiac metabolism"

@AranyLab @PennMedicine & colleagues

Read the review: https://t.co/qx9hd1lQkF

#50YearsofCell

[The Arany lab @AranyLab]

We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! https://t.co/EAaKaI104X

[The Arany lab @AranyLab]

it's been a while since we posted... Here our recent review w/ @Rongtian2 on HUMAN cardiac metabolism in @Cell_Metabolism : deep dive going back 50+yrs - turned out to be >300 refs! Much is known, much MORE needs figured out... https://t.co/vAR9M2d6dq

[PennCVI @PennCVI]

CVI's Highlighted #PapersoftheWeek https://t.co/3NuWQBtD4a

[The Arany lab @AranyLab]

Translating metabolic and cardiovascular research into effective treatments: What’s next? Some thoughts from several of us on the topic, in this issue of Cell: https://t.co/o6mDdLr6hN
@JuleenRZierath @JolandavanderV4 @Alicardsdoc @rosenzweig_a @DebMuoio

[The Arany lab @AranyLab]

@SeanM_Wu @IntMedAbel @UCLAHealth @AHAScience @BCVSearlyCareer @Joseph_C_Wu @Rongtian2 @RonglihL Appreciated the shoutouts, thank you Dale -- wonderful talk, as always!

[Boa Kim @BoaKim5]

I am pleased to share a preprint ‘HIF2α-dependent inhibition of mitochondrial clustering of glutaminase suppresses clear cell renal cell carcinoma’.
https://t.co/HzNP2OsKk6

[The Arany lab @AranyLab]

A few days late:  Congratulations to Daniel @daniel_baker_j for winning the 2024 @Phacilitate Young Scientist Award from Advanced Therapies Awards — including Glittering Gala dinner in Miami !

[Travis Hinson @TravisHinson]

New manuscript from our group studying DCM-TTNtvs and transcriptional modulators that reverse haploinsufficiency. https://t.co/Iumz1hfdgE

[Ben Prosser @Prosser_Lab]

Interested in TTN/DCM?
Check out current edition of @jclinicalinvest.
2 new reports: 1 by us w/ @Arany Lab and 1 from Miklos Kellermayer, plus commentary by @TravisHinson and Stuart Campbell.
We know a lot more about TTN pathomechanisms!
...and we know what we don't know. 🧵1/4

[The Arany lab @AranyLab]

14 key points from our recent review on peripartum cardiomyopathy #PPCM in @NEJM , summarized in @ACCinTouch , thank you @MelindaDavisMD. https://t.co/Vnha2SN42O

[The Arany lab @AranyLab]

@NBCNews Thank you for featuring our work looking at delayed diagnosis with peripartum cardiomyopathy #PPCM. Important story to get out there!

[NEJM @NEJM]

Review Article by Zoltan Arany, M.D., Ph.D. (@AranyLab): Peripartum Cardiomyopathy https://t.co/C7N3RGjIJY

#Cardiology

[The Arany lab @AranyLab]

Our latest review on peripartum cardiomyopathy #PPCM in @NEJM this week -- review of mechanism, genetics, clinical management, epi and prognosis -- lots of unknowns, huge racial disparities. Hope you enjoy it! https://t.co/hj1bzY3eUI

[Penn Medicine CSO @PennMedCSO]

High fat consumption & blood pressure elevation ft. @BoaKim5, @WencaoZhao, Soon Tang, @MGLevin, @_AyonIbrahim, Yifan Yang, Ling Lai, Jian Li, @FitzGerald__Lab, @AranyLab (@PennCVI/ @PennIDOM) Emilia Roberts & Richard Assoian (@PennSysPharmATT) https://t.co/uVOpjjEw2u

[The Arany lab @AranyLab]

Cool:  Lauren has just been selected to serve as the intern on the American Society of Nephrology Policy and Advocacy committee for Jan-Dec 2024 !  First non-postdoc/fellow that they’ve accepted, apparently! Congratulations !! @metabolauren @ASNKidney

[The Arany lab @AranyLab]

Deadlines are approaching for @KeystoneSymp #Cardiometabolic Diseases: #EthnicDiversity in #PrecisionMedicine, this February in Vancouver! See scholarship, abstract and discount reg dates: https://t.co/bGxHDiF8Ue #KSCardiometab24 #Cardiovascular