Asad Malik

Londoner doing his PhD at the @mrcppu working on elucidating LRRK1 regulation and function

[Asad Malik @asadm96]

@HTovell @mrcppu @JeanMarcTaymans @UoDLifeSciences @The_MRC Thank you Dr Tovvs!!! 😁😁😁

[MRC PPU @mrcppu]

Thank you Hannah Tovell and Alexandra Newton for your thoughtful commentary on Asad Malik’s #LRRK1 paper https://t.co/HK8EUNk6Tf
@HTovell @NewtonLab @asadm96

[__as_n_ Kinas_s @ChasingKinases]

Solving the LRRK jigsaw piece by piece:

Protein kinase C switches on the LRRK1 kinase - simply by phosphorylation.
https://t.co/jcIlcFzMp0

@biochem_journal @asadm96 @chatterjeedeep

[MRC PPU @mrcppu]

Excited to announce our study describing unexpected mechanism of LRRK1 kinase activation by PKC-phosphorylation of the GTPase domain, is in press https://t.co/SOIZ5cmlnA @biochem_journal

[Asad Malik @asadm96]

@HTovell Thanks @HTovell!!! 😀😀

[MRC PPU @mrcppu]

Congratulations to Xingui Liu and Alexia Kalogeropulou on there just published #LRRK2 #PROTAC paper (https://t.co/5Aypn1z1q3) see here https://t.co/WzhFEFMMre

[LRRK2 Central @LRRK2_central]

Excited to announce preprint from Alessi & Knapp labs describing new kinase activated by PKC isoforms through an unexpected mechanism: https://t.co/PuWHWDUJBN ​#LRRK2 #LRRK1 #PKC @ASAP_Research @LRRK2_central

[Asad Malik @asadm96]

Very excited to finally share the PKC-LRRK1 story with you guys 😁

[MRC PPU @mrcppu]

Excited to announce preprint from Alessi & Knapp labs describing new kinase activated by PKC isoforms through an unexpected mechanism https://t.co/FRQrq6dIfS #LRRK2 #LRRK1 #PKC @ASAP_Research @LRRK2_central

[MRC PPU @mrcppu]

MRC PPU researchers working hard on #WorldParkinsonsDay to make the next discoveries that could lead to better tests and treatments for #Parkinsons #ParkinsonsUKinScotland @ParkinsonsUK @ASAP_Research @MichaelJFoxOrg #WorldParkinsonsDay2021

[Miratul Muqit @miratul_neuro]

Out Now! Our preprint of global #proteomics analysis of #mitochondria in #neurons led by Odetta @mrcppu and Alban from @jwadeharper1 lab @HarvardCellBio leading to definitive roadmap of physiological #Parkin substrates #Parkinsons #PINK1 #TeamScience
https://t.co/NJ8RXFv8vO

[Asad Malik @asadm96]

Ecstatic to have made the cover of BCJ! Congrats to all involved!! 😁😁 @PPPublishing

[MRC PPU @mrcppu]

Asad Malik's study comparing the #LRRK1 and #LRRK2 pathways makes the cover of the most recent issue of the Biochemical Journal https://t.co/wg2TEy06cG @PPPublishing

[Yogesh Kulathu @YKulathu]

We’ve posted our work on characterising Nsp3 from #SARS-Cov-2 @biorxivpreprint. We find extended Nsp3 is a more active protease compared to PLpro. We engineer nanobodies that bind to and inhibit Nsp3 which will be useful tools to dissect Nsp3 biology.https://t.co/0D7bakCa1O

[Sven Lange @Sven_M_Lange]

Our contribution to understanding and overcoming SARS-CoV-2 is now available in pre-print! @LeeAArmstrong2 @YKulathu @mrcppu

[MRC PPU @mrcppu]

New preprint from the Dario Alessi lab "Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms" https://t.co/ElLOT5DvBy

[Asad Malik @asadm96]

@HTovell @mrcppu Thanks Dr Tovvs!!!! 😁

[Asad Malik @asadm96]

Glad to finally share my first pre-print with you guys!! 😁

[The Science of Parkinson's @ScienceofPD]

New @biorxivpreprint from @asadm96 & @mrcppu colleagues reinforces the idea that the LRRK enzymes have evolved as major regulators of Rab biology; Interesting: Widely used LRRK2 inhibitors being developed for #Parkinsons do not inhibit LRRK1
https://t.co/vW9ZnIKeEH

[Bill Carton @CartonBill]

Great experience getting to give a flash talk on my PhD research! 😁

[MRC PPU @mrcppu]

Position available: We currently have a Postdoctoral Researcher position available in the lab of @MahimaSwamy. Further information and how to apply can be found here https://t.co/nxHfMLAKeq #lymphocytes #immunology #Salmonella #Listeria #Toxoplasma #proteomics

[MRC PPU @mrcppu]

Great to be back #WeAreTogether

[Gopal Sapkota @gpsapkota]

My lab is looking for two Postdocs to join us for two collaborative projects with Janssen Pharmaceuticals. Details linked. Informal enquiries welcome. https://t.co/soBb8HhTzT
https://t.co/YJGQ57Wti6
@mrcppu @sapkota_mrcppu @UoDLifeSciences