Alex Sampson

PhD student @PSIOxford @OxfordVacGroup - interested in Immunology, Virology and Vaccines, previously worked as a mixed vet in the Outer Hebrides 🐕 🦠

[BensenHsu @BensenHsu]

The researchers wanted to test a new type of cancer vaccine called a "neoantigen DNA vaccine" in patients with triple-negative breast cancer (TNBC). TNBC is an aggressive type of breast cancer that doesn't have certain receptors, making it hard to treat. The researchers believed that the neoantigen DNA vaccine could help the immune system better recognize and attack the cancer cells.

The neoantigen DNA vaccines were found to be safe, with only mild side effects. The vaccines were able to trigger immune responses against the cancer mutations in 14 out of the 18 patients. Compared to a group of similar TNBC patients who did not receive the vaccine, the vaccinated patients had better outcomes, with 87.5% being cancer-free after 3 years.

full paper: https://t.co/x76JfNi4co

[Cell Press @CellPressNews]

Online now! The cryptic immunopeptidome in health and disease.
Check out this review from @IRIC_umontreal Claude Perreault & team in @TrendsGenetics #ASHG24 https://t.co/OF7tx3caee

[Louis R Nemzer @BiophysicsFL]

Not DNA
Not RNA
Not even epigenetic marks

Inherited amyloid proteins
https://t.co/j5lLkOELko

[Amesh Adalja @AmeshAA]

“The virus—a member of the Rhabdoviridae family—is transmitted by vectors that include sandflies, mosquitoes, and ticks.” https://t.co/MMPGZeg2HV

[Global Health NOW @ghn_news]

The rollout of two malaria vaccines this year marks a pivotal moment in the long fight against the disease—potentially saving the lives of tens of thousands of children. https://t.co/OU8dmiC4yS

[Lawrence T Wang @Lawreate7]

We co-published b2b papers describing >400 human monoclonal antibodies against the malaria blood-stage antigen RH5! These data will guide testing of current RH5-based vaccines in Africa and improvement of future vaccine candidates.

https://t.co/ldnyVG4dPg
https://t.co/1z5dLhIeSp

[Neil Stone @DrNeilStone]

Look at that beautiful ZERO..no HIV transmissions in over 2000 women who had a twice yearly injection of Lenacapavir.

Is this is how we are finally going to end the HIV pandemic?

Here's the full paper

https://t.co/NWWt0djpaA

[The Veesler Lab @veeslerlab]

We are so happy to share that the monoclonal antibody therapy we described is advancing to the clinic

1/4

https://t.co/jdOupRRUI7

[Renfeng Li @RenfengLi]

Our latest study introduces a new way in targeting Epstein-Barr virus (EBV)-associated cancers using a novel approach called CRISPR/dCas9-mediated EBV reactivation (CMER). Here’s a deep dive into our findings! 📜👇

[Faith Osier @FaithOsier]

Soooooo pleased our work is finally OUT @ImmunityCP 🎷🎷🎷🎷 Thanks to the amazing team @KEMRI_Wellcome @OgwindiT @rjogwang @rheneenaila @vizzardmetrix and many others!!! @ImperialSci @Inst_Infection @wellcometrust @ImperialMed

[Oxford Vaccine Group @OxfordVacGroup]

We're thrilled to announce that Prof. Teresa Lambe OBE has been elected to the Fellowship of the Academy of Medical Sciences! 🏅

Join us in celebrating the powerful impact of Prof Lambe's work on global health! 🌍👏

@UniofOxford | @OxPaediatrics

[Amesh Adalja @AmeshAA]

“84% reduction in cervical cancers” https://t.co/15YXuiZyFH

[Mark Suzman @MSuzman]

44 years ago, @WHO officially declared the world free of smallpox – an incredible feat made possible by a life-saving vaccine and global efforts to make it accessible to communities around the world.

#WorldSmallpoxDay is an important reminder of this achievement, and that vaccines are still one of the most impactful public health interventions we have to save lives.

And thanks to organizations like @gavi that work with governments and partners to deliver vaccines where they're needed most, greater progress is possible.

By working together, we can ensure no person dies from any vaccine-preventable disease - from polio to cervical cancer and more - and achieve a healthier, more prosperous world for all.

[Rhoda Meek @wodieskodie]

I'm angry about housing again and slightly less nuanced than usual. It's tiring being even handed all the time and it doesn't seem to be getting us anywhere. 👇

https://t.co/qavjQT4WMF

[The Veesler Lab @veeslerlab]

How is the human adaptive immune system responding to MERS-CoV infection? Find out by reading our @biorxivpreprint led by @AminAddetia
@HHMINEWS
@UWBiochemistry

1/16

https://t.co/pZlgbaZgR8

[U of Saskatchewan @usask]

Deer in N. America have been ravaged by a disease caused by infectious misfolded proteins.

#USask's Dr. Scott Napper is among those fighting to save them—and, in doing so, helping to protect people against a similar scourge.

Read more via @TheAtlantic: https://t.co/ll4ZTSk1cI