3 studies testing Perioperative immune bases therapy (EVP or Gem/Cis/Durva) in muscle invasive bladder all have shown an OS advantage vs standard of care. KN905 (EVP) is distinct in that it’s in a cisplatin ineligible population (accounting for the poor performance of the control arm). It’s also a smaller trial. The control arm of KN-B15 performed slightly better than NIAGARA (Gem/cis for both), but the trials are otherwise similar. The pCR in the EVP trails and the consistent efficacy of EVP is striking. #GU26
Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation
A Randomized Clinical Trial
https://t.co/ViQTBACbME
ACRO recently collaborated on a consensus statement on standards for dose evaluation and reporting in patients with multiple courses of #radiationtherapy. The policy review is now published in @TheLancetOncol. Check it out: https://t.co/qt4IQM2pWV
💡New article from Radiation Therapist Vickie Kong and team looks at time toxicity in CBCT-guided radiation therapy using a retrospective analysis🔗: https://t.co/j6GwJRaJsQ
Nice paper on abdo/pelvic sarcoma in Advances from the MDACC team.
Well planned and delivered VMAT is incredibly safe, very low toxicity risk.
Also a demonstration of how high grade liposarcoma locally recurs a lot!
Don’t sleep on pre-op radiation for these folks.
In this new #RedJournal article, the authors share practical strategies for delivering SABR and LDRT in patients with widespread polymetastatic disease. Read more here: https://t.co/XWvmsQxAj2
New in the #RedJournal: replanned TROG 12.01 unilateral cases to define guidelines for unilateral RT planning with maximal midline and contralateral sparing. @TROGfightcancer#RadOnc#HNcsm https://t.co/yvE7RTRk3A