Early @CSHL postdoc Elisa de Stanchina made a big splash studying the ARF tumor suppressor. She now runs the world’s best preclinical modeling core @MSKCancerCenter, where she continues to work with our lab on a daily basis. -SWL #LoweLab25
Full online version of our recent manuscript is now available! We find that a key transcriptional regulator of proteostasis (HPK-1) has unique functions within distinct neurons to promote healthy aging! https://t.co/vsXjZFj9Jx @eLife
Led by @AVSamuelson@ThakarLab, a stellar grp of postdocs/grad students👇 identified a kinase (HPK-1) in C. elegans that helps maintain homeostasis & likely mitigates natural age-associated physiological decline-Cool work! @UofR@eLife#URochesterResearch https://t.co/P72v00Luye
Congratulations to Dr. Adam Cornwell for completing his PhD! Dr. Juilee Thakar and I co-mentored Adam; he's amazing! One more paper on transcriptional regulation of dietary restriction and aging to finish writing! I cannot wait to see his future success!
@millerlab@UWBiochemistry Dana, this has been so much fun! So happy to be talking science and visiting with all the amazing faculty and students! Thank you so much for inviting me! ❤️
Today’s @UWBiochemistry seminar is Andrew Samuelson who is going to tell us about transcriptional regulators of proteistasis and longevity from C. elegans nervous system
My 1st student #AndySamuelson worked on mechanisms of apoptosis & holds the world record for manually counting dead cells. He went on to do a postdoc w/ @Gary_Ruvkun where he became interested in aging, which he studies in his own group @UofR. Check it out! –SWL #LoweLab25 (2/3)
@LoweLabMSKCC@gary_ruvkun@UofR 300,000+ cells as a grad student, over 1,000,000 worm observations as a post-doc. Not sure whether that's a triumph or just sad! I used to have little sympathy when I got complaints about manual scoring, but we now have lifespan machines in the lab too.
loving the @dungeonsanddads podcast (up to E12). @HardcoreHistory reference was a great easter egg. Cannot help but notice that @willbcampos sounds EXACTLY like Dan Carlin. Alter ego?!?!
I’m excited to share our manuscript that on Friday graduated from preprint to published article: https://t.co/RxFWBwZM0s
We have developed our imaging platform “the Lifespan Machine” to compare behavioral aging (sometimes called “healthspan”) and lifespan at high res. (1/7)
@AgingBiology Very brave of the EiC to come to this decision, and a real shame their requests were ignored. Aging Cell has been a great journal. Rethinking where to submit both a manuscript and perspective article we were considering sending there.