Patrick Bhola

[Joan Montero @JoanMonte]

Our work has been highlighted by @Nature, along with @DrTonyLetai @PhilippStaber @soragnilab and many others. Special recognition to @amanzano94 for his excellent work. The future of precision medicine is functional! @TheSFPM

https://t.co/nxb2DV2zfv

[Patrick Bhola @bholapat]

Mentoring young smart scientists is truly a privilege. Gabriella Antonellis from @mtholyoke started her PhD at @harvardmed this year. Very impressed by her intelligence and toughness during her time at the LFPM and @DrTonyLetai lab. Can’t wait to see what she does next!

[Gianmaria Liccardi @Giammy_L]

PhD stundentship available in the Genetic instability, Cell death & Inflammation lab @BCCologne @UniCologne We offer an interactive & highly collaborative environment surrounded by experts of the field at the forefront of scientific technology.Apply below
https://t.co/cvrxp4jpJJ

[Patrick Bhola @bholapat]

Looking forward to this #SFPM talk by @SanfordSimon . Sandy and team and @fibroregistry have done outstanding work characterizing FLHCC and are using functional approaches to identify therapies. Great example of bedside to bench and then back to bedside research.

[The Society for Functional Precision Medicine @TheSFPM]

Join us next week, Sept 13th @ 11:30 EDT for our SFPM Virtual Monthly Seminar featuring
@SanfordMSimon
as he discusses "Functional Precision Medicine for Effective Therapeutics for Cancer: Lessons from Fibrolamellar Hepatocellular Carcinoma"
Info/link: https://t.co/ohnuFm7onq

[Kristopher Sarosiek @CellDeathLab]

➡️Join us at the next BCDI meeting on Monday Sept 11th at 3PM on the Harvard Med Quad (Goldenson 122) for exciting discussions led by @TheLeeLab on cell death in response to transcription blockade and @OylerYanivLab on cell death in infections. More info: https://t.co/uOJiL13B18

[Science Magazine @ScienceMagazine]

School closures across Germany at the onset of the #COVID19 pandemic may help explain a concurrent surge in mental health problems for adolescents, finds a new @ScienceAdvances study. https://t.co/DCUDjDUgOg

[Dana-Farber News @DanaFarberNews]

Last night at Gillette, Bruce Springsteen gave a shoutout to @danafarber & Dr. Paul Richardson before singing his hit song, Thunder Road. Thank you, @springsteen!

[Patrick Bhola @bholapat]

@snbhatia Congrats to Nour-Saida!!

[Patrick Bhola @bholapat]

@sorger_peter @JiaRenLin Work by @AtreyiMukherji @emmalyn_lecky Gabriella Antonellis, Rebecca German and @DrTonyLetai. Thanks to collaborators: @KimmieNgMD @Dr_KMcQueeney @sorger_peter @JiaRenLin Ewa Sicinska. And our great environment: https://t.co/tYsImOrzmS @HiTSatHarvard @DanaFarber @harvardmed (7/7)

[Patrick Bhola @bholapat]

Why do some cells survive or die in response to chemo? One reason: #tumorheterogeneity of apoptotic priming. Now out in @ScienceAdvances, our new tech to identify features of #singlecells that are highly or poorly primed for apoptosis (https://t.co/yzniGTU7JY) (1/7)

[Patrick Bhola @bholapat]

@sorger_peter @JiaRenLin In some (though not all) #coloncancer PDX models, we found that poorly primed subpopulations (SP) expressed high levels of targetable proteins including Mcl-1 or Her2. This could lead to personalized strategies for drug combinations – though this strategy needs validation (6/7)

[Eric Topol @EricTopol]

It's pretty impressive that vaccines directed to the ancestral strain spike from 2 years ago, w/ the virus that's evolved thru >290 million confirmed cases, and now to the hyper-mutated Omicron, have preserved efficacy of near 90% vs severe disease with a 3rd shot

[Patrick Bhola @bholapat]

@AlanaWelm @biorxivpreprint @huntsmancancer @BryanWelm @GertzLab @VarleyLab @oesterreichs Awesome paper. A great example of how drug screens can alter patient care.

[Patrick Bhola @bholapat]

@shimada_kenichi Great tool Kenichi. Congrats!

[Patrick Bhola @bholapat]

@NiTriona @CatrionaM_D @ScienceAdvances @RCSI_Irl @RCSI_Research Congrats Catriona, Triona & team. A great example of how chemical screening leads to biological insights.

[Triona Ní Chonghaile @NiTriona]

Excellent paper describing paths to resistance of targeted agents - epigenetic resistance evolving to genetic https://t.co/DT7iti7Tev