Álvaro Lorente Macías

Postdoctoral researcher at @BOOMchemistry @EdinburghUni | 👨🏻‍🔬💊 Chemistry, Drug Discovery, Kinases, Bodyboarding, Hot Peppers |

[Álvaro Lorente Macías @boilingstone]

If you are interested in drug discovery and want to know more about all the approved small molecule kinase inhibitors, their medical indication, pharmacology and original synthesis, check out our last perspective! @ACSBioMed @EdinUni_IGC @BOOMchemistry
https://t.co/mDDZCkdoha

[Andrew Wood @AndrewWoodLab]

Interested in using degron tagging to study the function of your favourite protein in genetically engineered mouse models? Check out our review covering recent work in this area: https://t.co/9DKLmjaH5h

[Diego Oyarzún @doyarzunrod]

🌞Delighted to see our work with @VSmerBarreto
@jucaacoco @BOOMchemistry and the Carragher lab on featured in the press today!

https://t.co/XEnDNl90hK

https://t.co/smjTAM2Crh

[Diego Oyarzún @doyarzunrod]

💊📢 New paper on #AI for #drugdiscovery in @NatureComms

We discovered three senolytics - compounds that kill 'zombie cells' in therapies vs cancer and others #aging

https://t.co/AhvUW5j8WO

The most fun collab led by @VSmerBarreto with @jucaacoco lab

#compchem #synbio

[Álvaro Lorente Macías @boilingstone]

@BOOMchemistry @JACS_Au Congrats @SYC_Chm @BOOMchemistry excellent work!

[BOOMchemistry.com @BOOMchemistry]

Congrats to Shiao for her work @JACS_Au! @BOOMchemistry Excited with the potential of this targeted strategy. https://t.co/SaSRpmDwxy

[BOOMchemistry.com @BOOMchemistry]

See our last work here: https://t.co/yaIbhHObAs
After years of research, we show "Pd-triggered local chemotherapy" works in vivo and can solve inherent DMPK issues of a chemotherapy drug such as 5FU @ACSBioMed @EdinCRC @EdinUni_IGC @CRUK_BI

[Simone Hendrikse @s_hendrikse]

Interested to learn more on how molecular organisation, handedness and configuration can aid in synthetic biomaterial design? Check out our recent review here ➡️ https://t.co/MVaViiW8AY @ChemSocRev @rcontmont, Amanda Ellis, @PalliThordarson and @jonathan_steed

[BOOMchemistry.com @BOOMchemistry]

For those interested in #bioorthogonal catalysis, check out this new application just published in @angew_chem in collaboration with @BeckerLabCRTD https://t.co/4UtlJzFOtU

[ACS Publications Bio & Med Chem Content @ACSBioMed]

Interested in the chemistry behind approved kinase inhibitors? Check out the comprehensive perspective in Journal of Medicinal Chemistry by @BOOMchemistry here:
https://t.co/xl5hhaKgvJ

[Álvaro Lorente Macías @boilingstone]

@EdinCRC @EdinUni_IGC Congratulations to all the team involved @BOOMchemistry! Awesome news!!💊

[Edinburgh Cancer Research @EdinCRC]

Nuvectis Pharma has licensed rights to develop and commercialize a novel, SRC/YES1 inhibitor discovered at the CRUK Edinburgh Centre @EdinCRC of the University of Edinburgh’s Institute of Genetics and Cancer @EdinUni_IGC. Read more on Yahoo! Finance 👇:
https://t.co/8mStXJuImD

[BOOMchemistry.com @BOOMchemistry]

10 years of research culminates with this work. Our most important contribution to the cancer field. Joint effort from @EdinCRC, @MRC_CRH and @CIB_CSIC!! https://t.co/Ih9SrFi44w

[Álvaro Lorente Macías @boilingstone]

Novel Purine Chemotypes with Activity against Plasmodium falciparum and Trypanosoma cruzi https://t.co/taN2vhzcBX @MDPIOpenAccess @ISGLOBALorg @ffarmaciaUGR @genyo_pts @jjdmochon @BOOMchemistry

[Charles Williams, PhD (My views are my own) @cwilliamszf]

Synthesis and screening of 6-alkoxy purine analogs as cell type-selective apoptotic inducers in Jurkat cells https://t.co/ZxfYyfZFGI

[Álvaro Lorente Macías @boilingstone]

Check out our synthetic strategy to diversify purine libraries for drug discovery. Online on @ChemRxiv
https://t.co/dVcucjj1yc @BOOMchemistry @jjdmochon

[Álvaro Lorente Macías @boilingstone]

@mariadolores_mg @longlabstanford @Stanford_ChEMH @StanfordPath Enhorabuena!😃

[Álvaro Lorente Macías @boilingstone]

@Antonio_DG_ @Stanford @StanfordMed Enhorabuena Antonio!!

[Álvaro Lorente Macías @boilingstone]

@ana_aperezl @NatureProtocols Congrats! Great work!!

[Álvaro Lorente Macías @boilingstone]

A further step in the development of a RIOK2 chemical probe. Congratulations to the @UNC team!
@thesgconline @rsc_medchem #darkkinase

https://t.co/AKIrbMN2Bx