T. Bugra Gungul

[nature @Nature]

Nature research paper: A brain reward circuit inhibited by next-generation weight-loss drugs in mice

https://t.co/tVeGcG985m

[Christopher Deppmann @deppmann]

Out in Nature today: how next-gen GLP-1 drugs cut cravings, not just hunger.
Congrats to co-first authors Lizzie, Bugra, and Isabelle in @GulerLab lab traced the circuit — drug → central amygdala → less dopamine in reward circuits. Mostly Ali's lab; we got to contribute. Proud of this team.
https://t.co/SylGxi026e
#neuroscience #UVA

[Eric Topol @EricTopol]

Discovery of a new brain reward circuit in the amygdala for small molecule (pill) GLP-1 drug effect, unlike the injectables (hypothalamus), as shown in mice
https://t.co/3lkfxROh5Z

[NIH @NIH]

NEWS: Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings. 🧠
Read the full story ➡️ https://t.co/SuaCnWD7iS

[T. Bugra Gungul @bugragungul]

@So_Steculorum @LCReimon Amazing story! Congrats!!

[Zhenggang Zhu @ZhenggangZhu]

(1/n) Why is it so hard to stop eating when something tastes amazing? Our new @ScienceMagazine paper reveals that dopamine helps sustain our drive for tasty treats—and may explain how anti-obesity Ozempic tames those urges https://t.co/pXgG2RLfSd

[T. Bugra Gungul @bugragungul]

@ErezUzuner 🖤🖤

[T. Bugra Gungul @bugragungul]

Excited to share two big highlights from my research journey!

My abstract “A Brain Reward Circuit Inhibited by Next-Generation Weight Loss Drugs” was chosen for an SfN press conference — <50 selected out of 10,000+! We’ll be sharing our work to the media this November.

[T. Bugra Gungul @bugragungul]

Grateful to share our work with the scientific community & the public — and to our amazing team: Elizabeth Godschall, Isabelle Sajonia, my PI @AliDGuler & collaborators @deppmann @AUGCsoup

[T. Bugra Gungul @bugragungul]

Also, next week I’ll present at GRC on catecholamines: molecular, circuit, behavior & brain disorders — joining top scientists to discuss neuromodulatory systems.

[T. Bugra Gungul @bugragungul]

@yulonglilab Amazing tool!! Can’t wait to start using them

[Daniel J Drucker @DanielJDrucker]

A dedicated neural circuit through which small molecule GLP1RAs modulate reward processing, suggesting broad therapeutic potential in conditions of dysregulated dopamine signaling including substance use disorder and binge eating
https://t.co/SQJNvrJNmp

[Ali D. Güler @AliDGuler]

You can read more about it here: https://t.co/QZXP0fABjO Send us feedback on how we can improve our manuscript. All this work was led by three very talented graduate students: Lizzie Godschall @LizzieGodschall, Buğra Güngül @bugragungul and Isabelle Sajonia @isabellesajonia. 15/

[Ali D. Güler @AliDGuler]

GLP-1 receptor agonists (GLP-1RAs) are transforming the treatment of obesity and diabetes (and more). Our recent pre-print examined next-gen small molecules mimicking GLP-1, using humanized mouse models to uncover how they interact with brain circuits driving food consumption. 1/

[EuroFoot @eurofootcom]

🇹🇷👏 Commiserations to Türkiye on their #EURO2024 exit...

A team with immense passion that produced several high tempo, entertaining matches!

With Arda Güler, Yıldız, Yılmaz, Kadıoğlu etc, they will definitely be back... 🌟🌟

[BPT @bpthaber]

TEŞEKKÜRLER BİZİM ÇOCUKLAR 🇹🇷

A Milli Futbol Takımımız, Hollanda’ya 2-1 mağlup olarak EURO 2024’e çeyrek finalde veda etti.

Yaşattığınız her şey için teşekkür ederiz. Sizinle gurur duyuyoruz. 🇹🇷🐺

[T. Bugra Gungul @bugragungul]

Getting addicted to these Lelechas. Thanks to my friends from 🇨🇳

[T. Bugra Gungul @bugragungul]

Go 🇹🇷!

[T. Bugra Gungul @bugragungul]

Neurons in the central amygdala just threw the ultimate glow-up party! They brighthened my day 🎉🧠
Image credit: @LizzieGodschall

[T. Bugra Gungul @bugragungul]

Nocturnal researchers 🙃