Thanks again @SoleimanpourLab for the opportunity to be involved and to #MarieGasser for her vital input! Also grateful to the ever-resourceful @carapetop for her help!
Our new mouse models of glucokinase MODY and permanent neonatal diabetes reveal an additive and sex-dependent effect on insulin secretion of glucokinase activators and GLP1RA. https://t.co/RpRjn6Uk8w. @CRCHUM @HIRN_CC @ImperialMDR
RESEARCH | @carapetop, K Iwasaki, @caguayo et al. (@JoslinDiabetes):
#Exercise training decreases pancreatic #islet senescence through #glucagon and #AMPK signaling in mouse and human islets, which could have implications for #T2DM therapeutics.🐭👥
https://t.co/PLOsu5sKgf
Enjoyed an amazing @CIHR_IRSC@BT1D_CA in person team mtgand knowledge exchange event for our precision medicine in #T1D grant last week w/ this fantastic team!! @guy_rutter, @carapetop, Herb Gaisano, Fei Kang, Dana Greenberg, Pere Santamaria, Giada Ostinelli and Shadai Salazar
Congratulations to @carapetop for publishing her amazing work. And thank you to our amazing collaborators for their unwavering help and support @guy_rutter @LaurieGoodyear @roelandmiddlebeek @NatMetabolism@JoslinDiabetes@harvardmed https://t.co/ecW3EEJnWn
#exercise training in part via glucagon, leading to activation of 5′-AMP-activated protein kinase (AMPK) signalling, decreases senescence in pancreatic #islets offering promising therapeutic implications for #T2D@NatMetabolism https://t.co/BMqH4AfVZS
Back to my AMPK roots and a fantastic collaboration with @caguayo and @carapetop. Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence | Nature Metab. @CRCHUM @HIRN_CC @cusm_muhc https://t.co/5PmPmz9JOT
What an Amazing Week at the DDEA Summer School! 🌞
What was your favourite part? 💡
A huge thank you to our participants, speakers, workshop leaders and organisers for making this Summer School such a great experience – and to the sun for shining all week.
See you next year!🚀
Our latest @sennetresearch manuscript on #senescence, "SenNet recommendations for detecting senescent cells in different tissues", has just been published with @SpringerNature in @NatRevMCB. Read here: https://t.co/OxjPybVkqC
Je tiens à remercier les @FRQ_NT de soutenir ma carrière en recherche. Comme moi, joignez votre voix à celle de la #communautéFRQ et affichez votre soutien à la recherche !
https://t.co/kmqFJyS5a3
Warmest congratulations to our latest FRQNT PhD studentship awardee, @carapetop. She’s starting from a fantastic place with some exciting data on senescence and beta cell function in vivo already in the bag. Watch this space! @CRCHUM@HIRN_CC@thesugarscience@caguayo !
The dos Santos lab is recruiting candidates interested on a postdoctoral fellow position, to investigate gene regulation control of normal and malignant mammary development. Check it out!
So grateful for presenting at such an amazing place during @cshlmeetings. I want to thank my mentor @caguayo for all the support and ongoing encouragement!