Now @doug_loesch talking about genetic prediction of protein levels using UKB-PPP data. Spoiler alert: you can already download the data from https://t.co/35303j8fg8! #eshg24
Excited to share our new preprint describing updates to the @PGSCatalog (https://t.co/FDKoTDWCHc ) and the PGS Catalog Calulator (pgsc_calc), a new tool for reproducible PGS calculation in the context of genetic ancestry (https://t.co/VB3xXP5EMb). Just in time for #ESHG24!
/🧵
Very excited to share the first manuscript out of my PhD presenting our analysis into the genetic architecture of gene expression and splicing using blood RNA-seq of 4,732 blood donors from the INTERVAL study. (1/7) https://t.co/SkOUaRNfJK
New preprint just dropped!
https://t.co/2DdekETSr4
Here, we show that NMR biomarker scores combined with PRSs and SCORE2 may have moderate population health benefits for 10-year CVD risk prediction prevention
Thread 1/3:
@intipedroso @minouye271 @NatureComms Thank you for the kind words 🙂. While we did not directly compare TWAS to FWAS, we do expect that the model captures the synergies emerging from the complex interactions of imputed enzyme levels in the metabolic network (indeed, that’s one of the points of using models!)
@martaroqueta Sense entrar en el debat del hijab, la comparació no té ni cap ni peus. Fer exercici i una bona dieta són beneficiosos per la salut i redueixen el risc de malatia (e.g malalties cardíaques o diabetis tipus 2)
Comorbidity GWAS identifies loci that are not discovered in single-disease GWAS. The model (latent feature allocation) is a matrix factorisation method that learns comorbidity topics and assigns topic weights to each individual for GWAS.
https://t.co/ufp9R1sUIx
@DoblatgeCatala Doncs al final he aconseguit que m'aparagués el català😅. He començat a reproduir la película en català al ordinador, he tancat sessió al mòbil i he tornat a fer login. Llavors desde el móvil podía continuar la película en català i triar català en altres películes.
🎉 New paper! 🎉
How to estimate the carbon footprint of computations, in practice? With @minouye271, we discuss the different options in this Comment just out in @MethodsPrimers
Full text: https://t.co/SzEfsT6z6O
And a lot of resources on https://t.co/HObEYM4fmi 🌱