Fabio

[Fabio @change_states]

@nickandre @drrollergator Inference on production process when they're doing production.

Imagine you're baking a cake and you capture temperature, humidity etc. via sensors. They continuously capture the data and train a model. Then they use that model to play out what if scenarios.

[Fabio @change_states]

@elonmusk And how exactly do you differentiate that alignment from random chance?

America had incredible prosperity in the late '40s, '50s and '60s, and yet the birth rate is far higher than it is now.

[Fabio @change_states]

@NatalieKPierre What are the detours for cyclists and pedestrians?

[Fabio @change_states]

@martinharriman1 @ShaneWenzel It shows how people like to make intellectually dishonest arguments.

None of those products, nor production thereof releases toxic air pollution or GHG emissions to any order of magnitude.

[Fabio @change_states]

@BioLayne Yet there appears to be plenty of nuance there.

Elite cyclists far outlive elite powerlifters. Yet no one would accuse them of having more muscle than the power lifters.

So one could make the argument. This is just a proxy measure for exercise, the true driver.

[Fabio @change_states]

@ToYourHealth101 Not quite.

If it's reasonable to assume you may be killed, you are justified in using deadly force.

[Fabio @change_states]

@BioLayne The Bacon they replaced it with is not?

[Fabio @change_states]

@ChrisMasterjohn How did they submit a paper on models that weren't even released at the time of submission. Llama 3.3 for example was not released until December 6, 2024.

[Fabio @change_states]

@alexleaf I have begun to wonder if IPF and ASCVD have the same root cause, but acting on different tissues in the body.

Would be great if these two fields shared notes. I think IPF is a better progression model to understand how both work.

Won't happen until minds are open.

[Fabio @change_states]

@Nate_Hartz_ @AviBittMD Cut drug patent durations in half.

[Fabio @change_states]

@EricTopol Has it been compared to a suitable drug or vaccine that would eliminate the typical confounding variables?

Socioeconomic class, accessibility of healthcare, patient compliance, etc. If not, it would seem misleading to draw those conclusions.

[Fabio @change_states]

@CoachPaulBrake @MarkJCarney Matthew 12:36–37:

"But I tell you that everyone will have to give account on the day of judgment for every empty word they have spoken. For by your words you will be acquitted, and by your words you will be condemned."

Unless you're a prophet, heed the teachings of Christ.

[Fabio @change_states]

@AlecStapp @elonmusk It can be simplified: It's entropy.

Nature solved this problem by giving things a limited lifespan. Public institutions don't have this feature no matter how sick they are. It's difficult for them to die.

[Fabio @change_states]

@liz_churchill10 I really wish X forced people to answer a few trigonometry questions. Then we could filter on passed / failed those tests.

[Fabio @change_states]

@wholemars But overfitting isn't a real problem.

[Fabio @change_states]

@GraceOnFire2 @acoyne The separatists need to think about what happens when the cost of oil drops in the future as modern energy alternatives continue to improve and plummet in price.

I don't want to downplay the importance of this industry. But where is it in 25 years?

[Fabio @change_states]

@blacljk Then move to the US and enjoy paying to 20k USD a year for health care.

[Fabio @change_states]

@TrumpDailyPosts Yet another well thought out screed.

[Fabio @change_states]

@MichaelMindrum And getting unstuck from the current orthodoxy may allow investment into other modalities on a disease that's so pervasive where even a small number of non-responders to current therapies is a great thing. It can translate to many additional lives saved.

[Fabio @change_states]

@MichaelMindrum Assuming this data can be replicated. I would have a hard time understanding how you couldn't overturn the current understanding.

In fact, the disconfirming evidence has always been there in therapies that lower ApoB without reducing the risk of ASCVD.