Christophe Lancrin

Molecular Biologist | Passionate about cell identity, single cell biology, hematopoiesis, regenerative medicine | Supporter of gender balance in science

[Christophe Lancrin @clancrin]

Delighted to share our work on CD44 @NatureComms! Great work by @morgan_oatley, @ozgevargel & the rest of the team. Excellent collaboration with Sarah Teichmann, @vallens & @kiran_r_patil.
@embl, @sangerinstitute #stemcells #metabolism #scRNAseq https://t.co/JMApZNKGVU

[Christophe Lancrin @clancrin]

Congratulations to Nina Schmolka for her first paper as a group leader!

Targeted CRISPR-Cas9 screening identifies core transcription factors controlling murine haemato-endothelial fate commitment

https://t.co/BzVybyuMiC

[Gülce Perçin @GulcePercin]

Check out our new paper on embryonic macrophages in the bone marrow, now published in @NatureComms — made possible by a truly FANTASTIC TEAM!
@waskowlab

https://t.co/5exkM0fce7

I first shared this story at @ISEHSociety 2023 online — and now it’s out!

[Diana Passaro @DoctorDianaP]

Still thinking of #endothelial cells lining #vessels as a simple uniform barrier?
You’ll be surprised by how diverse they truly are!
👇🏻📑Have a look at our review to explore how these cells orchestrate #bonemarrow fate across life stages & #leukemia

https://t.co/rU3qUCetbD

[Vijay Sankaran @bloodgenes]

Delighted to have our preclinical study led by @RichardVoit on a universal gene therapy approach for #DiamondBlackfanAnemia by regulated GATA1 expression published in @CellStemCell today: https://t.co/Vkd7yfHHjH

[Historic Vids @historyinmemes]

In 1922, a group of scientists went to the Toronto General Hospital where diabetic children were kept in wards, often 50 or more at a time. Most of them were comatose and dying from diabetic ketoacidosis. Others were being treated by being placed on an extremely strict diet, which inevitably led to starvation.

These children were essentially in their death beds, awaiting what was at that time, certain death. The scientists moved swiftly and proceeded to inject the children with a new purified extract of insulin.

As they began to inject the last comatose child, the first one to be injected began to wake up. Then one by one, all the children awoke from their diabetic comas. A room that was full of death and gloom, suddenly became a place of joy and hope.

In the early 1920s, Frederick Banting and Charles Best discovered insulin under John Macleod at the University of Toronto. With the help of James Collip, insulin was purified, making it available to successfully treat diabetes. Both Banting and Macleod earned Nobel Prizes for their work in 1923.

In the same year, Banting, Collip, and Best decided to sell the insulin patent to the University of Toronto for $1.

Banting famously went on to say, "Insulin does not belong to me, it belongs to the world."

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Cecilia Pessoa @cica_dups]

Thrilled to share my paper! 🙌https://t.co/uD6QnUU1OL It was an incredible experience working and exploring such a fascinating story. Huge thanks all co-authors, they r amazing ppl, and everyone in the Zon Lab @leonard_zon for all their support both in and out of the lab! 😍

[Pereira Lab @CellReproLab]

1/23 We are excited to announce that our most recent study “In vivo dendritic cell reprogramming for cancer immunotherapy” was published in @ScienceMagazine.
https://t.co/yPDqKmpGnn
Here is a summary of what we discovered!

[Miki Ebisuya @EbisuyaMiki]

Very happy that our STEM CELL ZOO paper received the GSCN Publication of the Year Award!
All thanks to the co-authors (or stem cell zoo keepers) 🐭🐰🦏🐮👩‍🔬🐒

Here's a link to the paper:
https://t.co/7Zk791AJKs

[Dominic Grün @dominic_grun]

Human multilineage bone marrow organoids!!
What a beautiful system...

https://t.co/4YSukMXk2V

[Magdalena Zernicka-Goetz @ZernickaGoetz]

What is the origin of our body? Our paper @CellCellPress shows that when a human embryo is one day old and comprises just two cells, only one cell will create most of the fetus in addition to placenta, while the other cell will create placenta.
https://t.co/88l48YezzA

[Sara Formichetti @SaraSciFormi]

2nd work from my PhD is out!🤩Mammalian Ogt (enzyme of reversible intracellular glycosylation aka O-GlcNAc) is an X-linked essential gene. We use a complementary approach to the direct removal of O-GlcNAc (the other paper) to study the role of this PTM in embryos: 1/9🧵

[Massimo @Rainmaker1973]

This is a coloured scanning electron micrograph (SEM) of a red blood cell (erythrocyte) squeezing through a capillary.

This is where the oxygen-exchange with the surrounding tissues happens. Magnification: 9000x.

[🔬 SciencePhotoLibrary]

[Wonder of Science @wonderofscience]

Carl Sagan explains how the ancient Greeks knew the Earth was round and calculated its circumference over 2,000 years ago.

[Lee Grimes Lab @LeeGrimesLab]

🚀 Launching our #SingleCellAtlas: a deep dive into human bone marrow with paired CITE-seq and high-dimensional flow cytometry! Led by @XuanSeanZhang and @annie_song_b published in @NatImmunol. https://t.co/ysX8j42ATw 1/3

[Daniel Lucas @DanielL84885058]

I am really pleased to share our latest manuscript, just published @Nature! You can access the manuscript (open access) here: https://t.co/qVDuJDz61s
Special thanks to Maria Carolina Florian for the great commentary: https://t.co/5Zz3ZO38R4

[Science girl @sciencegirl]

If 100 people lived on Earth

[Massimo @Rainmaker1973]

This is from The Tonight Show with Johnny Carson aired on May 20th, 1977.

Carl Sagan says something very important, a strong message that didn't lose any validity since then.

[Prof. Feynman @ProfFeynman]

Teach your children how to think, not what to think.

[Irene Cantone @CantoneIrene]

Looking for a #postdoc in the sunny side of the Italian peninsula? Interested in #chromatin mediated #epigenetic mechanisms of #sexbias in autoimmunity? I have an opening to start immediate (or by August 2024). Have a look 👇🏻