Human hippocampal CA3 damage disrupts both recent and remote episodic memories – our new paper in @eLife
tl;dr: amnesia extended up to 50 years prior to damage (flat gradient); linked with disrupted integration in the MTL subsystem of default network
https://t.co/lN2Yyf89j7
New paper in Cell Reports
CA2/3-dependent stability of frontal mnemonic representations predict episodic deficits in human amnesia
w/ lead author @Memory_Miller
https://t.co/JEBu3LwEhm
Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | https://t.co/pjI36Z7wLi
How does blood perfusion map onto canonical features of brain structure and function? @AsaFarahani investigates @PLOSBiology ⤵️
Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation.
https://t.co/hVIihT0acP
A short thread follows for those interested
The human consciousness signal has been identified. Groundbreaking @ScienceMagazine study convincingly showed that the activity of certain nuclei in the human thalamus are needed to consciously perceive what we see.
Rethinking memory impairments: Retrieval failure - new long-form synthesis in @APA Psychological Review with @AlfeiJoaquin, Ralph Miller & Gonzalo Urcelay:
https://t.co/LtRkuR93rp
🚨Very excited to share this new work showcasing the independence of face perception & face memory, at least under most circumstances. Check out Michal's thread for details, including a very intriguing interaction that emerged when we taxed working memory with a face distractor.
Bittersweet as this project began in 2022 with the late Eleanor Maguire. Those who know her will not be surprised to know she continued working on
this up until the end. Ably abetted by @alhickling@yanwu_neuro
This work was made possible with the support of @wellcometrust
Really pleased this new work, led by Tom Miller, is out. The study involves individuals with episodic amnesia, secondary to focal, bilateral hippocampal damage (N=18), and advances earlier work in @eLife@Brain1878 with a new cohort and task-based fMRI focused on memory retrieval
Bittersweet but excited to share the preprint: "Decoding memory dysfunction in hippocampal amnesia." fMRI RDMs were used to assess how focal human hippocampal damage affects mnemonic representations across the autobiographical network. @clive_rosenthal
https://t.co/rgIDYgFzoi
How does uncertainty shape learning? Our latest preprint investigates how pupil-linked arousal interacts with prediction errors in uncertain environments.
With @PrashantiGanesh@donner_lab Radek Cichy @nico_schuck@carstenfinke and me
Our new preprint is out! We show that pupil-linked arousal encodes uncertainty-weighted prediction errors to learn under state uncertainty 🎉
https://t.co/lGs1Fj660v
Many thanks to Tobi Donner @donner_lab, Radek Cichy, @nico_schuck, @carstenfinke and @rasmusbruckner !!
The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon
@ndosenbach @gordonneuro
https://t.co/MggGxwKqUp
I am pleased to announce the publication of our special issue on scientific histories of hippocampal research in the journal Hippocampus! This special issue contains articles by many influential contributors to our field. https://t.co/6LoCtvc5xy
*** Two doctoral scholarships available by Max Planck School of Cognition @MPS_cog and Berlin School of Mind and Brain @MindaBrain funded by DAAD ***
👉 Two topics: (1) Heart and Brain & (2) Autoimmune #encephalitis
👉 International applicants only
https://t.co/Wb1kOjjzqW
In the action-mode, arousal is heightened, attention focused externally, and plans are converted to goal-directed movements and updated based on feedback, such as pain. The brain’s action-mode is created by a dedicated action-mode network (AMN) https://t.co/KUFnXpSyIa. In the brain’s mode continuum, the AMN’s action-mode sits opposite the DMN’s default-mode for self-referential processing, counterbalancing each other as yin & yang. AMN dysfunction might be key in pain, apathy, Parkinson’s, etc. New NRN piece with Marc Raichle & @gordonneuro. Short 🧵 ⬇️
Very pleased to share our latest work. Using machine learning, we show that #Parkinsons related falls can be accurately predicted up to 5 years in advance. This gives us the opportunity to start thinking of effective care planning for enhancing PD management.