In the newest Behind the Breakthrough episode, Kathryn Moore, PhD, explains how heart disease is driven not just by cholesterol, but by inflammation. Her discoveries may help stabilize—even reverse—plaque at its source.
Full video: https://t.co/dTJ0dXAWwW
Find all you need to know about CARINH, an intriguing long noncoding RNA whose unique regulatory functions intersect the seemingly distinct processes of innate immunity and cancer development, in our recent publication: https://t.co/zaQpZfnYMY
@GourvestM@Non_Coding_RNA
2025 is off to a great start with our publication describing the regulation of innate immune transcription factor IRF by the long non-coding RNA CARINH. @ycyr06@NYULHCVRC@LSAjournal
https://t.co/b8whcem7py
The antisense lncRNA CARINH acts as an additional regulatory layer of antiviral immunity through coordinated regulation of the transcription factor IRF1 and downstream interferon-stimulated genes. @coenvansolingen@ycyr06@nyulhcvrc https://t.co/npzIn1gy6T
I am THRILLED to share my latest work from my time as a postdoc in the Rayner lab @KateyRayner published today in @NatureCVR !!🥳🎉
We know that the #spleen produces immune cells that worsen #atherosclerosis, but why this occurs is not well understood… 1/
https://t.co/7X25G9jfeQ
Congratulations to Chiara Giannarelli @ChiaraGiannare1, winner of the Jeffrey Hoeg Arteriosclerosis, Thrombosis & Vascular Biology Award for Basic Science and Clinical Research! Presented at #VascularDiscovery24
Can we harness #immunometabolism to promote atherosclerosis regression? Check out our findings in PNAS showing the role of the IRG1-itaconate axis in atherosclerosis @ycyr06@FazliBozal. Thanks to our collaborators @GiannarelliL@NYULHCVRC@PNASNews 🧵https://t.co/uoli69o8v4
Happening Now (6-7:30) @coenvansolingen presents poster 673 on the role of lncRNA CHROMR in licensing interferon signaling responses in macrophages. Learn how CHROMR can reduce inflammation in atherosclerotic plaques. #vasculardiscovery23@ahascience@nyulhcvrc
Our postdoc Gabriel Barcia has looked in-depth at the immune cell landscape of regressing atherosclerotic plaques. Join him today in Grand Ballroom Salon G (4th floor at 5:45) at his oral abstract presentation (160)! @ahascience#vasculardiscovery23@nyulhcvrc
Don’t miss the #vasculardiscovery23 Investigator in Training Award Finalist @ycyr06 who will present his work on Netrin-1 highlighting the emerging role of the cytoskeleton as a signaling hub regulating immunometabolism. Visit poster 572 on Friday @ahascience@nyulhcvrc
Are you wondering how #longnoncodingRNAs modulate inflammation in atherosclerosis? Come check out poster 696 and chat with @GourvestM about an exciting story on Friday 12th (6:00-7:30PM) #vasculardiscovery23
@ahascience@nyulhcvrc
Come watch @KristinMWang present her work titled Gene Regulation by RNA Granule Formation in Atherosclerosis (abstract 104), on Thursday May 11th at 12pm (Session 1A Grand Ballroom Salon E). #VascularDiscovery23@ahascience@nyulhcvrc
The #NAS160 Research Briefings will start with a talk from #NASmember and cell biologist Kathryn J. Moore, who will explain how noncoding RNAs, the so-called "dark matter" of the genome, help in cholesterol regulation.🧬
Learn more and register: https://t.co/Jgg3ZBUG71