Colin Magowan

BioTech BD. Posts about the High Sierra, geology, cell biology, vaccines, and anything in between.

[Colin Magowan @colinmagowan]

@andrewpannu RNA; looking forward to reading through your findings

[joanna schroeder @iproposethis]

Instead of cropping up in people in their 60s or 70s after decades of exposure, it is now afflicting men in their 20s, 30s or 40s, said Dr. Jane Fazio, a pulmonary critical care physician... Some California patients have died in their 30s.

https://t.co/dvbnyxhtx0

[Colin Magowan @colinmagowan]

@bitterwaterblue @MojaveDesertLT Not to diminish your good observation… but I love the map’s “local government” descriptor in the Owens Valley. Unintentionally hilarious!

[Pliant Therapeutics @PliantRX]

Extremely excited to share additional positive data from our Phase 2a INTEGRIS-IPF trial in #idiopathicpulmonaryfibrosis. Join us and a pulmonology key opinion leader tomorrow morning at 8 a.m. EST for our call and webcast. Read more: https://t.co/Sz9ysjFUz9

$PLRX

[Lasker Foundation @LaskerFDN]

Congratulations Richard O. Hynes, Erkki Ruoslahti, and Timothy A. Springer, 2022 #LaskerAward winners! — “for discoveries concerning the #integrins—key mediators of cell-matrix and cell-cell adhesion in physiology and disease”.
@MIT @sbpdiscovery @harvardmed
#Lasker2022

[Pearl Freier @PearlF]

Biotech & healthcare investors, whose funds manage $68B, said latest proposed Senate bill would cause 235 companies to lose funding. They estimated this impacts 800K jobs in US. 87 CA companies, 58 in MA, 25 in NY. Some listed for cuts incl founder-led biotechs. See pgs 21-31 1/n

[Pliant Therapeutics @PliantRX]

Excited to share the positive data from our Phase 2a INTEGRIS-IPF clinical trial. Please join us tomorrow morning at 8 a.m. EST for our conference call and webcast. REad more: https://t.co/AioPQrCAyh

#idiopathicpulmonaryfibrosis $PLRX

[Colin Magowan @colinmagowan]

@AppleHelix @stuartacook1 @AlpBugraBasat Yes. This. Critical.

[Colin Magowan @colinmagowan]

@JanEhses Maybe this is helpful on Merck’s ILT4: DOI: 10.1158/1078-0432.CCR-21-2160

[Colin Magowan @colinmagowan]

@pkedrosky Backcountry skiing not for first, but rather last descents…

[Colin Magowan @colinmagowan]

@wolfejosh While working on a food allergy product, came across the influential Shelly Nutt of the Texas Peanut Producer Board (and other peanut affiliations) Untoppable https://t.co/jd4Iv4WgqA

[Colin Magowan @colinmagowan]

Congratulations to the Pliant and Novartis teams! Excited to help support what promises to be a fruitful and productive collaboration.

[Endpoints News @endpts]

Novartis hands off $80M in cash to partner up with a top biotech player in the fibrosis sector https://t.co/iHcT9PLxiY

[Colin Magowan @colinmagowan]

Reminded of a March 2019 Nature opinion piece from March arguing that massively increased Amazon deforestation is largely due to China shifting soy bean production from the US to Brazil as a result of the US-China trade war. see: https://t.co/PC6wZhjwUK

[Colin Magowan @colinmagowan]

@PeterGleick Oryx and Crake

[Colin Magowan @colinmagowan]

@jasmarce @gcbioinv This was disclosed at the end of the $BBIO S-1. Purchased from another large shareholder in a private transaction. Smart management of selling pressure...

[Colin Magowan @colinmagowan]

$GLPG 750 patient two active dose placebo controlled P3 study to start enrolling in November in idiopathic pulmonary fibrosis with FVC as primary endpoint. See https://t.co/qbx6Gst6qf

[Colin Magowan @colinmagowan]

Nice paper on a new cancer genetics-independent mechanism of ATR inhibition by Dr. Eric Brown and UPENN colleagues showing how specific genomic structures appear to contribute to fork collapse upon ATRi. See: https://t.co/ew6WaBHyIC Couple of interesting ATRi's in clinical dev.

[BioWorld @BioWorld]

.@TheWistar spinout Virion raises $5M series A to back IND filing for checkpoint inhibitor-powered vaccines to treat virally induced ID, cancer

[Colin Magowan @colinmagowan]

@jianguangchen @zbiotech Keep in mind they Agios reported median duration on therapy is 3.9 months (+ list ≠ cost)

[Colin Magowan @colinmagowan]

@dsobek @AndyBiotech Or the greater degree of total resection...