Coppola Lab

@UCLA Research Lab, within @UCLASemel, working to advance our understanding of the genetic architecture of neuropsychiatric disorders.

[Stefanie Alber @StefanieAlber]

Want to know about PTBP1 in adult sensory neurons? Check out our recent preprint:
PTBP1 Regulates Injury Responses and Sensory Pathways in Adult Peripheral Neurons https://t.co/qFDH7413TI

[Letizia Marvaldi @LetiziaMarvaldi]

I love this pre-print from @StefanieAlber & @MFainzilber! PLEASE RT!!! @MatthewZdradzi1 @Pabi_Sahoo @doron_ella @Nasic500 @giovannicoppoIa @CoppolaLab @jltwiss1

PTBP1 Regulates Injury Responses and Sensory Pathways in Adult Peripheral Neurons https://t.co/9h9rqVVe4M

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

so proud to see Dr. Francisco Lopera receiving an award at #AAIC2020 right now. Thanks @ytquiroz for initiating this honoring. @GBHI_Fellows @AgustinMIbanez @Mairoka @ASlachevsky @UCSFmac

[Gan Lab @LiGanLab]

Our R47H TREM2 study:
1/3 snRNA-seq from AD patients of common variant and R47H carriers revealed that R47H-associated microglial subpopulations have enhanced inflammatory signatures and hyperactivation of Akt. https://t.co/9t25FOW2Ri
@biorxivpreprint @biorxiv_neursci

[Miller Lab @MillerLabNeuro]

Beyond excited to see results from the SOD1 antisense trial in #ALS published in @NEJM. Congratulations to all parties involved!

@TimMillerNeuro
@ALSCenterWashU @WashUNeurology @biogen @ionispharma

https://t.co/MrAijQHB4D

[Towfique Raj @towfiqueRaj]

This is NOT the America I want to pass down to my child. We must all take the time to reflect on how we can all work towards better future. We must stand against all forms of racism and any discrimination. We stand in solidarity with peaceful protesters. #BlackLivesMatter

[Jesse Rissman @jesse_rissman]

As I mourn George Floyd's horrific murder & stand in solidarity with the Black community in my outrage against systemic racism, I realize I have much still to learn. The course I am currently teaching on the Neurobiology of Bias & Discrimination has never felt more necessary...

[Xia Yang Lab UCLA @YangLabUCLA]

UCLA leaders express solidarity with the protests against racial injustice https://t.co/M4VMNURooH
"We must never let that indifference to human suffering become our own. We must never deaden our hearts to the pain of others. Our fundamental values demand that we care."

[Jazlyn Mooney, PhD @Jazlyn_Mooney]

A thread.
I feel as though I am normally a pretty happy person, but these past few months have really caused me to reflect on who I am and where I stand in this world. I don’t often talk about these topics because I feel as though they are deeply personal, but now is the time. /1

[Stem Cell Podcast @stemcellpodcast]

New in @CellStemCell: A team led by Dr. April Pyle (@apyle) at @UCLAstemcell has created an atlas that tracks the development of human skeletal muscle from human muscle tissue and from pluripotent stem cell-derived myogenic cultures. https://t.co/Xdv7sndIK2

[Coppola Lab @CoppolaLab]

Work from our own Marisa Ramos!

[UCSF Fein Memory and Aging Center @UCSFmac]

Genetic screen in a large series of patients with primary progressive aphasia. Consistent with the finding that PPA frequency in dominantly inherited dementias is the highest in kindreds with GRN variants. https://t.co/mB6DfnjDuD @AlbaLanguage @giovannicoppoIa @Zachary94010852

[UCLA QCBio @UCLAQCBio]

Welcome to UCLA @hjpimentel!

@CompMedUCLA @dgsomucla

[FTD Registry @EndFTDregistry]

AFTD is hosting an “Ask the Expert: FTD and COVID-19” webinar, Friday, April 24 at 1:30 pm EDT/10:30 am PDT. The 1-hour event will cover advances in care and the impact of the COVID-19 pandemic on people with FTD and their families. #EndFTD REGISTER: https://t.co/THXS8AX5Ro

[UCSF Fein Memory and Aging Center @UCSFmac]

Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration. Plasma pTau181 identified amyloid β-PET-+ individuals. https://t.co/xPQ15DGxLn @EHThijssen @relajoie @leoiacca @SalvoSpinaSF @grinberg_t @RabLab_UCSF @JulioCRojas10

[UCLA Neurology @UCLANeurology]

How are stem cells used to help repair the damage caused by a #stroke? Dr. S. Thomas Carmichael was interviewed in a Facebook Live special "Ask the Stem Cell Team About Strokes" with the California Institute for Regenerative Medicine @CIRMnews: https://t.co/xeKB9ul5qo

[TweetALS @TweetALSMND]

Reduced #C9orf72 function contributes to neurotoxicity in #ALS #MND by inhibiting #autophagy according to a new study @NatureNeuro https://t.co/ZLtynzdNjS #LagierTourenneLab #ClevelandLab

[clarklabucla @clarklabucla1]

UCLA scientists study how intestinal stem cells age https://t.co/wRM3ZsvD4Q

[UCSF Fein Memory and Aging Center @UCSFmac]

Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy. Connectivity-based model can predict longitudinal spread of atrophy. https://t.co/CGnQTYAFFr @jesseaaronbrown @lee_suzee @SalvoSpinaSF @grinberg_t @CoppolaLab

[TweetALS @TweetALSMND]

Looking for a tunable scalable system to discover potential personalized strategies to bolster NMJs in #ALS #MND? Check out these results @CoppolaLab! #optogenetics

Establishment of a Human iPSC-Derived Neuromuscular Co-Culture Under Optogenetic Control https://t.co/wzlMkXxpzp

[UCSF Fein Memory and Aging Center @UCSFmac]

18 F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes. Limited sensitivity and specificity in patients with FTD and predicted tauopathy or TDP-43 pathology. https://t.co/A9rOSpV5ki @RabLab_UCSF @lee_suzee @SalvoSpinaSF @grinberg_t @AlbaLanguage @CoppolaLab