Sai

[Sai @cydatio]

@vasuman Haven’t worked in other domains, but are workflows general enough to make custom deployments scale across all these domains?

[Sai @cydatio]

@bubbleboi You can be confident and care

[Kat @katyenko]

Thank you to everyone who spent their Saturday with us at Ebolathon—and congratulations to the BuilderBlockers, Michael, @cydatio, and Rafal, who took an interesting synthon-aware Thompson Sampling approach to guide compound selection.

All submissions have been sent to our co-host, @onepot_ai, for synthesis before moving into pseudovirus assay testing. All assay data will be made public.

A special thank you to our judges—@andrei_tyrin, Andrii Kyrylchuk, Amy He, and Nina Jovic—for lending their time and expertise.

And thank you to our sponsors—@RowanSci, @boltz_bio, @OpenRouter, @modal, and @anyscalecompute for giving participants access to the models and compute needed to explore the challenge, and to @posthog for hosting us in their wonderful space!

[Sai @cydatio]

@katyenko Thank you (and everyone else involved) for organizing and hosting this! I had a great time and learned a ton!

[Sai @cydatio]

@jiratickets real

[Sai @cydatio]

@menhguin There's still some deep domains like healthcare (including rev cycle/the financial side) where agents (especially long-running) are still nascent

[Sai @cydatio]

@menhguin The Anthropic/OpenAI IPOs should extend the cycle at least into 2027 right?

[Sai @cydatio]

A little on the nose for the agent era (from The Art of Doing Science and Engineering):

[Sai @cydatio]

“Data analysis is the gateway to scientific reasoning” generalizes to non-scientific domains as well imo

[Kenny Workman @kenbwork]

https://t.co/H6YCz8Ni1V

[Sai @cydatio]

@jstn Isn’t this more a startup vs big corp thing?

[Sai @cydatio]

@yoobinray What do you think they should do instead? Something more focused on how computers actually work like CompE or EE?

[Sai @cydatio]

@joodalooped Was expecting like 3 types lol

[Sai @cydatio]

@rahulgs Why can't #7 in ngmi be durable assuming the task/benchmark can be specific to your product? Even if it's only more token efficient than the frontier, that can mean better perf for your product/ui -> more usage -> more feedback -> etc

[Sai @cydatio]

@adele_bloch @dejavucoder Indoor bouldering is a good place for this. There’s a natural slowness between trying the problem, resting, and people mingling around

[Sai @cydatio]

I swear every couple of months I come across a Borges reference lol. I’m gonna sit down and read a collection of his works someday.

Also, good post

[gabby @GabriellaG439]

New blog post: "A sufficiently detailed spec is code"

I wrote this because I was tired of people claiming that the future of agentic coding is thoughtful specification work. As I show in the post, the reality devolves into slop pseudocode

https://t.co/V86V7cjWpS

[Sai @cydatio]

@polynoamial @MillionInt @shyamalanadkat Because it won’t be efficient or for alignment?

[Sai @cydatio]

@poeticdweller Probably the same reason lifting is not cardio

https://t.co/okXLCgcELt

[Howard Luks MD @hjluks]

https://t.co/REq9mAU4bF

[Sai @cydatio]

@tszzl @QuasLacrimas When was the heyday of rationalism? I remember reading HPMoR when I was younger