David Sinclair says we’ll find out this year whether aging is reversible.
His lab reversed biological age in animals by 75% in six weeks. The FDA has cleared the first human trial.
Aging may be information loss.
Information can be restored.
Interesting
CELLULAR AGING BREAKTHROUGH
Scientists may have found a molecular blueprint to revive old cells. A new UCSF study identified four key transcription factors, E2F3, EZH2, STAT3, and ZFX, that can push aged cells back into a youthful state.
By reactivating this gene control network, old human cells regained higher energy levels, increased cell division, and younger gene expression patterns. In aged mice, activating one of these factors reduced liver fat and scarring and improved glucose metabolism, making old tissue function more like young tissue.
This discovery suggests aging isn’t just damage, it’s a loss of coordinated gene regulation that may be partially reversible. Instead of replacing cells or turning them into stem cells, this approach hints at resetting cells from within, opening a new path toward therapies focused on extending healthspan, not just lifespan.
@CoachDanGo Okay but does the circadian alignment from early eating outweigh the fasting benefits for mental health, or is it all about individual response?
@iamkamyabuch Yup. I wrote something because can't unsee how the intellectuals of our times seem to have just rediscovered Hindu philosophical thought.https://t.co/fjviUPUC7A
Just watched the Nikhil Kamath interview and can't unsee that the way current global thought leaders think, it's just Hindu philosophical thought through and through. Let me explain:
NET CONTRIBUTION
Elon: "A good life is when you make more than you take. Be a net contributor."
Hindu concept of Rna (debts) - we're born indebted to gods, ancestors, and society. Life well-lived = repaying through service (Seva).
Just watched the Nikhil Kamath interview and can't unsee that the way current global thought leaders think, it's just Hindu philosophical thought through and through. Let me explain:
ENERGY AS ULTIMATE CURRENCY
Elon: "In the future, energy will be the only real currency. You can't legislate it, you have to generate it."
Prana/Shakti. Hindu cosmology says the entire universe is modifications of cosmic energy.
Your boss will soon know EXACTLY how stressed you are 😰
Scientists created a forehead tattoo that reads your mind 🧠⚡
Real-time brain monitoring for:
✈️ Pilots (prevent crashes)
🚛 Truck drivers (stop accidents)
⚕️ Surgeons (life or death decisions)
89% accuracy predicting mental overload 📊
🧵 THREAD (1/3)
@daveasprey 2025 biohackers are ditching meat for fermented plants.
kimchi boosts gut health and cognition 10% more than steak (Nature Neuroscience, 2025).