Dan Okin

Physician Scientist @HarvardPulm @MGHmedicine | Post-doc in @jkagan1 lab | @RMedzhitov alum | Immunology and evolutionary biology

[Jonathan Kagan @jkagan1]

Who wants to discuss innate immunity and host defense?
Join us in Banff to share your exciting research.
https://t.co/0jzZ49WrJG

[BWFUND @BWFUND]

Application now open: Career Awards for Medical Scientists (CAMS) is a highly competitive program that provides $700,000 awards over 5 years for physician-scientists, who are committed to an academic career
Deadline: 10/07/25
https://t.co/9aNcOaa0Os
#bwfcams

[Dan Okin @danokin]

Check out this must read from @Lo_Zanzi and @dfrboehmer on IFNs👇🏻

[Ivan Zanoni @Lo_Zanzi]

#InterferonPower! Thrilled for our latest work @CellCellPress! With @dfrboehmer, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free link 👉 https://t.co/gYwGir0npB

[Dan Okin @danokin]

👇🏻👇🏻👇🏻Check out this great study on oxidized lipids and how they control inflammation!! Congrats @Lo_Zanzi !

[Ivan Zanoni @Lo_Zanzi]

#EpigeneticPower! Our #NewPaper @ImmunityCP shows that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2, blocking #IL10! https://t.co/4av5UPDe9r

[Dan Okin @danokin]

Congrats @XuZhouLab on a fantastic study, excited to see where you take this next!

[Xu Zhou (周旭) @XuZhouLab]

Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH https://t.co/VMQmTxQgLM

[Nature Rev Immunol @NatRevImmunol]

BRD4 acts as a pH sensor to tune inflammation https://t.co/VRM1hfqMQV

[Dan Okin @danokin]

@Noahpinion This article from March 17th… totally breaking news.

[Anh Cao @Anh_Immunology]

Finally, our study on caspase-11 and its CARD-recognized molecular pattern is out in Science Advances! A small step, but we hope it opens new directions for studying caspase-11 and its ligands. 🔬🚀 #Immunology #Caspase11 #ScienceAdvances

🔗 https://t.co/9isf3K7tcg

[Dan Okin @danokin]

Congrats on the great story @JelenaLab!!

[JelenaBezbradicaLab @JelenaLab]

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.@FabiAlexFischer https://t.co/t0wbhGxfty

[Dan Okin @danokin]

@samirzaidi @Yale @YaleCancer @ynhhealth Congrats Samir!

[Itai Yanai @ItaiYanai]

We have to stand up for science! Anyone who can join these rallies and believes that US science must be protected should come!

[Dan Okin @danokin]

@jmhorp @threadreaderapp unroll

[vitalik.eth @VitalikButerin]

The more I think about it, the more I think 2013-era morality is pretty much correct:

* free speech good
* starting companies and making good products good
* monopolies bad, vendor lock-in bad
* democracy good
* greed bad
* trying to achieve national security through oppressing people bad
* cosmopolitan humanitarian values, caring about faraway people, etc good

Things we've "learned" since then have been harmful more than helpful

[Dan Okin @danokin]

@mattyglesias Some may call it a party fowl

[Darby Saxbe @darbysaxbe]

I need people to understand how difficult it is to get an NIH grant. You spend months writing a proposal, following strict guidelines that include a detailed multiyear budget, bios of everyone on your team, plans for participant safety & ethical conduct. Then you send it off -1/n

[Dan Okin @danokin]

Congrats @Dr_KatieM and team at @DanaFarber on the wonderful work published in @SciImmunology today https://t.co/q8JusxDzY5

[Dana-Farber News @DanaFarberNews]

In a study published in @SciImmunology, led by @Dr_KatieM, @DanaFarber researchers have identified key factors that contribute to the success of donor lymphocyte infusion to treat relapse of acute myeloid leukemia after stem cell transplant.

Read more: https://t.co/ZljklwdYwv

[Dan Okin @danokin]

@jkagan1 @harvardmed @Anh_Immunology Congrats Dr!

[Dan Okin @danokin]

Wonderful piece @vcunningham and congrats on the new kid! Merry Christmas! 🎄

[Dan Okin @danokin]

@Jesse_A_White Congrats, great place to train!