Out now in @ScienceTM: An international research team including scientists from across @NIH identified a novel causative gene variant for APECED, a rare genetic autoimmune syndrome, with potential for targeted therapies. https://t.co/Tga7fS2zyc
Delighted to share our recent @NatImmunol study led by @YuanyuanGao6, @ywangCB, and @dchauss, showing that transcription factor EGR2 controls tissue- and disease-specific functions in pathogenic Th17 cells in the CNS. Many thanks to our collaborators!!!
https://t.co/OPx25oseSi
Looking for an updated review on the role of various transcription factors in #tregs ?
Look no further than this brilliant review in NRI by my colleagues @LuisTrujilloPhD@kazemianlab and @AfzaliBehdad.
New microcircuit in the fruit fly visual system allowing a single signal type to be used for multiple purposes: another layer to understanding neuronal networks & the visual process!
@BraunAmalia1 @mmerier089 @maxplanckpress@MPIforBI@CurrentBiology: https://t.co/gxrywhLrJI
#ICYMI: A study from researchers across NIH shows drugs suppressing complement C5 increase the risk of serious fungal infections, demonstrating the key role of locally-produced C5 in providing antifungal immunity. https://t.co/BCwA30qAxt
Single-cell or spatial?
Our new technology - Slide-tags - allows both in the same experiment, enabling true single-cell multi-modal spatial genomics
➡️ https://t.co/i1m5T4bEme
The @vahedilab and Henao-Mejia laboratories present their latest preprint titled "A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic
inflammation through 3D genome topology" https://t.co/Ek26gb9Ju5
Amazing week for #DeepLearning in #spatial#singlecell biology, with 2🔥new Graph Neural Networks methods!
1.STELLAR🇺🇸 @jure: a cell type annotation & discovery atlas-type framework
2.NCEM🇪🇺 @fabian_theis: an approach to infer cellular communication patterns
Deep dive below🧵
Thanks @NatRevImmunol for highlighting ours and others recent work on #VitaminD and #COVID19! Check out the the full article @ https://t.co/swC0Juvn7l @kazemianlab @AfzaliBehdad