Mihalis Lionakis

Physician-scientist #NIAID @NIH | #Immunology | #innate immunity | #Immunodeficiency | #Fungi | #Infection | Father | 🇬🇷🇺🇸 | Views are mine, not of US govt

[Mihalis Lionakis @LionakisLab]

We previously showed that APS-1/APECED features excess IFNg responses that can be targeted therapeutically (Oikonomou NEJM 2024). We now extend this to show that early JAK inhibition can intercept the development of irreversible autoimmune endocrinopathies
https://t.co/hqO3J2Wxag

[Mihalis Lionakis @LionakisLab]

Expanded diagnostic criteria in APECED promote earlier diagnosis which can improve patient outcomes

https://t.co/qZQxJLo5gH

https://t.co/vhj3VGnce2

@JCI_insight

[Mihalis Lionakis @LionakisLab]

In @elife: Selective JAK Inhibition Reveals Paradoxical and Hierarchical Control of interferon-γ-driven Autoimmunity in AIRE Deficiency https://t.co/TWcliQTSlG

[Mihalis Lionakis @LionakisLab]

@kmills711 Many kudos!!

[Mihalis Lionakis @LionakisLab]

@bwtrautner Congrats Barbara!

[Mihalis Lionakis @LionakisLab]

Great work, Kathleen! Many congratulations!

[Kathleen Mills, PhD @kmills711]

A million thanks to @tmhohl71, the whole Hohl lab 🍄, @LionakisLab, Amariliz Rivera's group @RutgersU, @WCM_IMP, and the folks @SciImmunology. If you'd like to read the paper 📰 and don't have access for any reason, I'm happy to send a copy, just let me know. End thread ☺️

[Mihalis Lionakis @LionakisLab]

A great lab to train! Amazing science, great mentoring!

[Chrysothemis Brown @themis_brown]

Interested in immunology and looking to gain research experience before applying to graduate or medical school?Join us! We're hiring a research technician https://t.co/UDRR4H3lj9

[Mihalis Lionakis @LionakisLab]

@BogunovicLab @stewart_ojay @KidsAtColumbia @SinaiImmunol Groundbreaking work that explains variable penetrance in inborn errors of immunity. Amazing @BogunovicLab, I look forward to your NIH visit next week!

[Mihalis Lionakis @LionakisLab]

@KuchrooLab @VanjaLazarevic5 @C_A_Spinner Great work, as always!

[Mihalis Lionakis @LionakisLab]

@mayer_barber @SciImmunology @bakerpaulj Great work Kat!

[Mihalis Lionakis @LionakisLab]

@IlievLab Kudos Iliyan!

[Mihalis Lionakis @LionakisLab]

@km_tsui @JacquesMeis @NEJM @AnuradhaMyco Thanks, Clement, the review was accepted before this 6th clade was revealed so unfortunately we could not add to the review but this is an important piece of new information and it suggests that there may be other clades that are yet to be revealed. Thanks!

[Mihalis Lionakis @LionakisLab]

Fun to write this review on Candida auris infections @NEJM with @AnuradhaMyco! Thanks Anu!

https://t.co/Qu0MURKitc

[Mihalis Lionakis @LionakisLab]

@OKurzai @NEJM @AnuradhaMyco thanks for pointing this out, Oliver, hope all is well

[NEJM @NEJM]

𝘊. 𝘢𝘶𝘳𝘪𝘴, a serious public health threat that may have emerged because of climate change, persists on human skin and inanimate objects, frequently causing difficult-to-control outbreaks in health care facilities. Full review with interactive map: https://t.co/nlzcy2bmMY

[Shankar Thangamani @ThangamaniLab]

Our recent study out today in @PLOSPathogens identified cell type specific immune responses to Candida auris skin infection using single cell transcriptomics. Thank you @LionakisLab, Mihai Netea and Vinod for collaborating in this study !
https://t.co/RHv2n3ZK9J

[Mihalis Lionakis @LionakisLab]

Thanks @NIAIDNews for highlighting our work!

[Mihalis Lionakis @LionakisLab]

@Lo_Zanzi @CellCellPress @achillebro Amazing as always! Great work!

[Mihalis Lionakis @LionakisLab]

Our synthesis of the genetics, immunopathogenesis, diagnosis, and treatment of inborn errors of immunity that impair thymic development and/or function. With Francesca Pala and Gigi Notarangelo @jacionline

https://t.co/pKIXD0EmOR

[Mihalis Lionakis @LionakisLab]

@pjmurray_lab @NordmannThierry Congrats for the great science and for persevering!