The Dominguez-Sola Lab

We study the biology of normal B cells & their cancerous counterparts. Affiliated with @IcahnMountSinai @TischCancer @SinaiImmunol.

[The Dominguez-Sola Lab @DDSoLab]

I think that the beauty (if I may) of this study is on the cell models that we built with @PapapetrouMDPhD. These are based on previous work in her lab https://t.co/JHXUY2DU36 and extremely valuable, it turns out, to understand how MYC works to transform cells.

[ISEH @ISEHSociety]

What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on https://t.co/8X4XaGpJpO

[The Dominguez-Sola Lab @DDSoLab]

More posts to follow here and on Bluesky, where we just started an account in case you’re interested.

[The Dominguez-Sola Lab @DDSoLab]

This is the latest work from the lab, in collaboration with Peter Heeger at @CedarsSinai. We had the precious help of many, including @FribourgLab, Alex Tsankov’s lab and @pardi_lab. You can find it at @JExpMed:

https://t.co/uwFMlZtEUL

[The Dominguez-Sola Lab @DDSoLab]

And we are back. Sorry for the radio silence to those that noticed

[ISEH @ISEHSociety]

What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on https://t.co/8X4XaGpJpO

[Keisuke_Ito_Lab @keisuke_ito_lab]

@Hema_News @IcahnMountSinai Congrats to David (@DDSoLab), Eirini (@PapapetrouMDPhD), and the team on how persistent MYC rewires epigenetic landscapes and TF networks, revealing sustained deregulation drives MYC-driven leukemic transformation. @ISEHSociety

[Fund NY Science @FundNYScience]

Over 600 New Yorkers attended our Virtual Town Hall today to advocate for state-based science funding! We were joined by researchers, patients, institutions, and elected officials.

[The Dominguez-Sola Lab @DDSoLab]

Support a New York State Biomedical Institute for a Healthier, More Affordable Future - Sign the Petition! https://t.co/h2gNMGqobD via @Change

[The Dominguez-Sola Lab @DDSoLab]

For those who were not aware of this initiative:

https://t.co/FL2btzNRds

[The Dominguez-Sola Lab @DDSoLab]

We are extremely grateful to @StBaldrick especially to Jack's Pack @jackspack10 ,(https://t.co/uqgFqSMIdN), for their support in our quest to find better treatments for Burkitt Lymphoma.

[St. Baldrick's Foundation @StBaldricks]

Your donation dollars are turning hope into work that saves lives. 💚 Nearly $1.2 million in new grants just announced, and you can learn more about what you helped make possible: https://t.co/LgVaiTvpob

[Journal of Experimental Medicine @JExpMed]

Dominguez-Sola @DDSoLab highlights work by Yada et al. (https://t.co/CmxKaxOKFo) which demonstrates that effective antibody affinity selection in germinal centers relies on the store-operated calcium entry component of the B cell receptor signaling network https://t.co/zgkOCpRCIR

[The Dominguez-Sola Lab @DDSoLab]

@HerranzLab @TischCancer @RutgersCancer @IcahnMountSinai Our pleasure. Excited to have you visit and talk about your lab’s research.

[The Dominguez-Sola Lab @DDSoLab]

@Joshilabyale Same here

[Dr Alex Pike @Alexandra_Pike]

A bunch of @StokesNeuro's trainees (from many points in time) put together a list of '10 simple rules for a supportive lab environment', inspired by the example he set. This has been a wonderful moment of reflection for me personally, as I start my own lab https://t.co/FctwQw0dFi

[Adrià Cañellas Socias @adriacanyellas]

Incredibly excited to share our article “Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells” published today @Nature. I hope that you like it! A big thank you to all the co-authors for all their hard work! Highlights in the🧵 1/20
https://t.co/FzNv9zCvgg

[Maly Cosco @malycat03]

Impactful words by @CarolynBertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!

[The Dominguez-Sola Lab @DDSoLab]

To those that make good things happen. #SinaiNPAW2022 #PostdocAppreciationWeek

[The Dominguez-Sola Lab @DDSoLab]

Definitely trippy https://t.co/MRyQZAg2NC

[The Dominguez-Sola Lab @DDSoLab]

@ZivShulman It was outstanding indeed. Won’t miss the next one. Thank you for everything, Ziv