One of the craziest things I learned last week at #AAI2024 was that we have more free-floating extracellular mitochondria in our blood than white blood cells. This was not in any textbook that I ever read!
https://t.co/wT3mQtZDyj
And the original paper:
https://t.co/9NNSVaGMrn
Very cool to see the same age reversal AAV-OSK therapy that cured blindness in mice & monkeys also reduce frailty & extend the lifespan of very old mice 💪 An important milestone 👏
I’m elated to share the first research article from the lab. This would not have been possible without the hard work from my lab members and collaborators. I also have a special thought for our co-author, Jay Shulkin, who passed away recently. See thread in the tweet below.
🔥A study led by @FelixFelxfel lab at @NeuroAlc describes a prefrontal cortex to lateral septum circuit suppressing social interactions with familiar mice and supporting social novelty preference in adult mice.
Now published on @CellCellPress 👇
https://t.co/4vJIoQSM98
📷IN/Cell
Nice article by @antonioregalado about the recent @rejuvenatebio result of using in vivo partial reprogramming gene therapy to extend lifespan of normal old mice.
https://t.co/yIhkLD7ORY
@MIT@antonioregalado covers our paper in @biorxivpreprint indicating epigenetic reprogramming can rejuvenate old mice and extend their lives: https://t.co/XDROuH8KUr
🚨A new partial reprogramming preprint from @rejuvenatebio with a nice lifespan extension result in old (124-wk) WT mice: 18.5 weeks of remaining life vs 8.9 weeks for control.
https://t.co/GtZZO6hEoY
H/t @realNathanCheng