Diptavo Dutta

Investigator @NCIEpiTraining / Interested in Statistical Genetics, Genomics and Genetic Epidemiology/Views and opinions are my own

[Diptavo Dutta @Diptavo]

Interested in statistical methods for integrative multi-omics analysis with new and exciting GWAS data?

I have a postdoc position available to work on statistical genetics/genomics methods in cancer.

Please #RT

https://t.co/TccroB2yW4

[Diptavo Dutta @Diptavo]

Happy to see this out. A super interesting finding - a variant found almost exclusively in Africans is associated with Burkitt Lymphoma. An enriching collaboration with @SMbulaiteye @BRGorman the EMBLEM team and folks at DCEG

[Sam M Mbulaiteye @SMbulaiteye]

Super excited to share our paper “A genome-wide association study identifies an African-specific locus on chromosome 21q22.12 associated with Burkitt lymphoma risk and survival”. This work should encourage more studies to understand the genetic basis of BL https://t.co/3Srv13GMg9

[Diptavo Dutta @Diptavo]

@guanghao_qi Congrats!! Wonderful news!

[ASA Section on Statistics in Genomics and Genetics @ASA_SSGG]

The Membership Engagement Committee of the @AmstatNews @ASA_SSGG proudly presents a panel discussion on "The Value of Postdoctoral Training in Statistical Genomics and Genetics." The 1hr session will be virtual on Mon January 27, 3-4:00 PM EST.

[Haoyu Zhang @AndrewHaoyu]

Check out the presentations from our lab and our close collaborators #ASHG2024. Such a hard-working year. So proud of the group!!! Very humbled to be able to work with so many great collaborators @xihaoli @XihongLin @GENES_PK @Diptavo @HongyuZhao2 @Tony_Chen6 @AlexiaDiasF

[Diptavo Dutta @Diptavo]

Work led by Nathan Huey and co-supervised with Nilanjana Laha @TAMUstats

[Diptavo Dutta @Diptavo]

New preprint !! sparse canonical correlation is incredibly useful to identify groups of closely correlated omics modalities.
Here we test which individual variables contribute to this "correlated" cluster using de-biased SCCA that enables asymptotic testing.

[bioRxiv Genetics @biorxiv_genetic]

De-biased sparse canonical correlation for identifying cancer-related trans-regulated genes https://t.co/Ye9VcI8NfW #biorxiv_genetic

[Diptavo Dutta @Diptavo]

Application in METABRIC data identifies 250+ genes trans-regulated by estrogen receptor related CNAs, including 5 which were not identified by standard linear regression. Better yet, with debiased SCCA we know which genes are actually associated to the CNAs and which are there just for correlation

[Diptavo Dutta @Diptavo]

Great to see this out. A comprehensive pleiotropic analysis showing widespread pleiotropy among GWAS significant variants.
But we also detect several SNPs that are highly trait/outcome specific !! Fantastic work led by @guanghao_qi with @nilanjan10c @alexisjbattle @DrDebashreeRay and co

[Guanghao Qi @guanghao_qi]

Pleased to announce that our paper has now been published in Nature Communications:
https://t.co/2e1hJh3S4B

[Diptavo Dutta @Diptavo]

Our followup study of the #renal cell carcinoma GWAS identified several genes in #kidney #transcriptome beyond those from GWAS. Additional analysis in other tissues and plasma #proteome. Now published in @AJHGNews
#NCI_ITEB

[Mitchell Machiela @mitchiela]

Our TWAS analyses in four normal and tumor #kidney transcriptomes and 48 GTEx tissues identified several important genes with relevance to #renal cell carcinoma overall and its subtypes.
https://t.co/BxaUvYEwkS
@Diptavo @NCIChanock

[Diptavo Dutta @Diptavo]

@josh_weinstock @EmoryMedicine Congrats 🎉🎉

[Diptavo Dutta @Diptavo]

Immersive presentations and words of wisdom by @mitchiela @MengjieChen6 and others on the importance of interdisciplinary collaborations in genomics today. webinar hosted by @ASA_SSGG

[ASA Section on Statistics in Genomics and Genetics @ASA_SSGG]

𝐑𝐞𝐦𝐢𝐧𝐝𝐞𝐫: 𝐇𝐚𝐩𝐩𝐞𝐧𝐢𝐧𝐠 𝐓𝐨𝐝𝐚𝐲 𝐚𝐭 𝟐 𝐏𝐌!

Join the @ASA_SSGG panel discussion on "𝐂𝐨𝐥𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐒𝐭𝐚𝐭𝐢𝐬𝐭𝐢𝐜𝐚𝐥 𝐆𝐞𝐧𝐞𝐭𝐢𝐜𝐬 𝐚𝐧𝐝 𝐆𝐞𝐧𝐨𝐦𝐢𝐜𝐬."

Registration (free but required): https://t.co/OTtEVitRFa

See you there! 😀

[Diptavo Dutta @Diptavo]

Grateful to @HGGAdvances for providing a platform for early career researchers in human genetics, to showcase their research.

Try out our method: https://t.co/47vkVCrY9b

Paper: https://t.co/FvlmlKI2UK

@BrianXinyu @nilanjan10c @NCIEpiTraining #NCI_ITEB

[ASHG @GeneticsSociety]

.@HGGAdvances sat with @Diptavo, PhD in the latest Inside HGGA to discuss his recently published paper, “Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability.” ➡️https://t.co/bnMt0G4xUG #ASHG #GeneticsDiscoveries

[Diptavo Dutta @Diptavo]

The first #STATGEN2024 organized by @ASA_SSGG was super fun with a great turnout. Had the privilege of chairing a session with talks from @guanghao_qi @kanishkadey @shang_lulu @bhattac_a_bt. Looking fwd to next year already

[Diptavo Dutta @Diptavo]

Glad to be a part of this fantastic effort and collaboration. Expanding our understanding of renal cell carcinoma genetics hugely. Stay tuned for several follow up analyses delving deeper into the translational impact of the results. @NCIEpiTraining #NCI_ITEB

[Mitchell Machiela @mitchiela]

Online today in @NatureGenet is a multi-ancestry #GWAS of renal cell carcinoma #RCC that identifies 50 novel loci, subtype specific loci for clear cell and papillary subtypes, and an African ancestry-specific association at VHL.
https://t.co/eDb4VA3BOu
@NCIEpiTraining #NCI_ITEB

[Diptavo Dutta @Diptavo]

Glad to see this in print now. New method to perform cross tissue TWAS. Spearheaded by the brilliant @BrianXinyu. Check out the method: https://t.co/47vkVCrY9b
@nilanjan10c @NCIEpiTraining

[Human Genetics and Genomics Advances @HGGAdvances]

📢New from @Diptavo & colleagues
📰 Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability
👉https://t.co/TdtVPTK2d8

[Diptavo Dutta @Diptavo]

Final days to apply!! Fantastic opportunity for aspiring trainees.

I will be looking for a postdoc with interest in statistical methods in genetics and genomics. @NCIEpiTraining