Shifting the pitch and contours of Waddington’s valleys, putative enhancers, and transcription through H3K27me3 chromatin in the endoderm. Find it all here: https://t.co/3VUYiyOFlo. Fantastic collaboration with @josh_brickman and @wendy_bickmore. Well done Jurriaan and @djmbio.
Preprint alert! 🎉I am excited to share the work from our enjoyable collaboration with @wendy_bickmore@josh_brickman labs. Investigating the role of PRC2 in stabilising the developmental transcriptional response during endodermal differentiation. https://t.co/gzaXozOrxW
🔍 Explore ligand-receptor signaling across the spatial and temporal landscape of human HSC development with our online tool - created in a fun collaboration with Omiqa Bioinformatics.
Link here: https://t.co/OAAKSExaOs
🧵 2/2
That's a wrap for Season 2 🔥
The last episode will be out in August, so stay tuned 🎶
Can't wait for Season 3 🎧
💌 ► Don't miss anything : https://t.co/Qrkf8J0q7z
🧪 A research team co-led by Drs. Stefano Rivella and Hamideh Parhiz performed in vivo #hematopoietic stem cell (HSC) modification by mRNA delivery.
Their research offers a nongenotoxic conditioning regimen for HSC transplantation!
@ScienceMagazine | https://t.co/WYstAe5KSl
Great paper out today, led by @JiroBecker and Satoshi Yamazaki, demonstrating the power of polymer-based cultures to clonally expand HSCs. A whopping 33,000-fold HSC expansion and the ability to select correctly gene-edited HSC clones for transplantation: https://t.co/GrZDbat8Je
We are expecting a large gathering of chromatin/epigenetics/transcription researchers from the UK and abroad. Anyone interested in sponsoring this event, please get in touch.
🥼 Researchers at @theCrick including @DrHHEncabo, @IVAramburu, and @VeniPap describe how TET2 affects human #neutrophil development and function.
TET2 loss in hHSCs produce a distinct neutrophil heterogeneity in #BoneMarrow and peripheral tissues.
👉 https://t.co/XSerCPy9jW
I’m very proud of @Amy_L_Hughes and the rest of the team @BiochemOxford on the final published version of our paper @NatureComms !🍾🎉
https://t.co/69BdoT4ZVT
a few details about the paper below if you are interested👇
It is with heavy hearts that we announce the passing of our beloved colleague and friend, C. David Allis. Aside from his groundbreaking contributions to biomedical science, David will be remembered for his warmth, humility, and relentless optimism.
Talibanss have banned all women and girls from the schools colleges unversitied and all the jobs in the name of Islam . Why have Indian Muslim personal board and other Islamic scholar not condemned this . Why . Do they agree with Talibans
Do extrachromosomal DNA (#ecDNA) cluster closely with each other to drive amplified transcription of their resident oncogenes in #glioblastoma (GBM) stem cells?
We have explored this in our paper out in @eLife now 1/10 https://t.co/sJf0S9I6Vh
Hot off the press ! 🔥 Our review focusing on Polycomb complexes and their influence on brain development has just been published in @Epigenomes 🧠 ….and it just so happens to be my first publication! 🥹🎊
No enhancer redundancy. Innovative combination of QSTARZ enhancer reporter and scRNA-sequencing shows distinct spatial & temporal activities of two PAX6 retinal enhancers. @uttley_kirsty@shiprabhatia@mrc_hgu@EdinUni_IGC
https://t.co/vQwU60rcBo
Excited to share our preprint investigating the activity of PAX6 retinal enhancers using the QSTARZ assay in zebrafish. Do overlapping enhancers have unique or redundant functions in development?🤔Live-imaging and scRNAseq says yes for these enhancers! https://t.co/aCuBfWqGhO
Postdocs need
At least, 20% hike in postdoc salary.
Sign on bonus that'll get a laptop.
Promising career prospects.
Healthy work environment.
Decent health insurance.
Relocation expenses.
Retirement benefits.
Proper leave plan.
5-day work week.
Better respect.
Child support.