Thrilled to share that, together with my colleagues @UoDCeTPD and collaborators @Boehringer, we report @ScienceMagazine the breakthrough discovery and characterization of a small-molecule that degrades most oncogenic mutant forms of KRAS. 1/8 https://t.co/PT8miaXUnR
So nice to see this paper out in its final form. Hope our learnings can help you identify and confirm true, on-target degraders!
Big thanks to the project team across both organisations @UoDCeTPD@Boehringer@alessiociulli
https://t.co/s5ehdxVcMN
Thrilled about our latest Pseudokinase research published today in @CommsBio, showing EphB6 power in promoting cell cell adhesion through formation of intercellular tubes. Many congratulations to our star PhD student @LungYu_Liang.
Proud to sign this open letter from the Australian health sector and join with @VACCHO_org and Victorian health leaders in support of a Yes vote in the upcoming referendum 🧵
#VoteYes
The Australian Centre for Targeted Therapeutics (ACTT) at @WEHI_research is hiring a Senior Research Scientist (Lead Scientist, Protein Biochemistry) to help develop novel targeted protein degrader drugs. Info and applications here: https://t.co/Tz5e5zIS54
Excited to be part of a new collaboration to address current gaps in Australia’s #DrugDiscovery pipeline, which has been awarded $9.75m from the #MRFF.
🧵1/4
💊to the Chemists looking for a Postdoc:
📢we have an open position in the targeted protein degradation & antibiotic research lab @theCrick!
🔗https://t.co/XuBlEXnUAn
PLease RT! We have 4x opening at postdoctoral level to join our new @CeTPD_Dundee. Covering all range of disciplines, both academic in @farnaby84 team and in our drug-discovery teams @Boehringer and @AlmirallUS. DM for informal enquiries https://t.co/gEF9R8NEG1
Taking a BiTE out of KRAS G12C drug resistant tumors with cell surface drug presentation. 🙏 @CraikLab for collaborating on our first adventure in biologics. @bignerdzzy@PRoh_94@UCSFCancer @HHMINEWS https://t.co/BlCu69WcGQ
Looking for an enthusiastic medicinal chemist to join @Sleebs_Lab@WEHI_research on an exciting oncology program in collaboration with an industry partner.
For further details,
https://t.co/cr0DmmhT3B
I'm really pleased to share a tool I developed with colleagues at Edinburgh University - designed to support academics in managing their research careers. 1/11
Will be great to bring together the Australian TPD community for #DegradersDownUnder, a hybrid conference on 12-13 July 2022, in person @WEHI_research and online. Free registration: https://t.co/mOSxbeddbB