Wei_如是我闻

Chromosome & Longevity science | Exploring how biology and AI can help humanity live better, longer lives | Building at the frontier of human potential

[Wei_如是我闻 @drwwwg]

Trump直接给国际足联主席本人打电话，要他“去看看美国队得的那张红牌”结果还真的缓期执行。相信不会有另外一个国家领导人能做出这种事情。但这就是典型的川普作风，不惧规则，永远为自己争取利益，美国的利益就是他的利益。这次最喜欢的球队法国，阿根廷，挪威和英国都在，一定是充满故事的一届世界杯

[Wei_如是我闻 @drwwwg]

AI 现在到底像不像 2000 年 .com 泡沫？

AI 技术还很早，但 AI 股票主题已经不早。

十年后真正的赢家，可能不是“模型最酷”的公司，而是控制分发、数据、工作流、算力成本和反馈闭环的公司。

你觉得现在更像 .com 泡沫的哪一年？

[News from Science @NewsfromScience]

For decades, biology textbooks have enshrined a simple rule: DNA is made by copying a template. After one enzyme unzips a DNA double helix into separate strands, another called a polymerase builds a complementary sequence, base by base, for each strand. Presto: two copies of the original DNA.

But new research into how bacteria defend themselves from viruses now shows this synthesis rule isn’t absolute.

Now, a team describes a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide.

Learn more: https://t.co/bpVgr0KMdR

[Elon Musk @elonmusk]

True currency is steadfast friendship

[Wei_如是我闻 @drwwwg]

@GrindeOptions 65%

[Wei_如是我闻 @drwwwg]

@alanchen 他应该说的miatake是鲍威尔，上次Kevin是runner up

[Mitch Guttman @mitchguttman]

What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency. https://t.co/8KwfJHQWTt

[Jack Zhang Lab @zhang_lab]

High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria https://t.co/YZZ2njfWd4
Check out my lab's first work on membrane proteins!
Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!

[Elizabeth Villa @TheVillaLab]

It cannot be done, they said.. It's too flexible, they said.. 😁
https://t.co/6wDKmXeXfL #NPC #teamtomo #integrativemodeling by @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech et al. Great collaboration w/ Qiang Guo, Brian Chait, Javi Fernandez-Mtnz, @RoutLab_RU @salilab_ucsf

[宝玉 @dotey]

这确实极具创意！让我们有机会感受一下AI所处的世界。

她先让GPT-4自己描述它所处的世界，然后用这个文本在Midjourney中生成图像，在Mubert中生成音乐，在Kainber AI中用图像生成视频，最后把视频和音乐一起放到RunwayML生成最终的视频。

这是GPT-4生成的对自己所处世界的文字描述：

“想象一下，一个光滑的金属球体，表面光滑，代表着模型中包含的大量知识。球体发出柔和的、脉动的光芒，在各种颜色之间变换，象征着人工智能在处理信息和产生反应时的动态性质。球体似乎漂浮在一个数字环境中，被数据流和代码包围，反映了人工智能背后复杂的算法和计算能力。”

[Wei_如是我闻 @drwwwg]

@WiwiSFC Emmm..

[Wei_如是我闻 @drwwwg]

@WiwiSFC played it for a while

[William J Nicolas @WiwiSFC]

Awesome!

[Merlin Lange @Merlin_Lange]

Another version of our recent video of the month in @Nature, capturing zebrafish embryo development #FluorescenceFriday #zebrafish #Microscopy (& thanks to @napari_imaging animation plugin)

[Wei_如是我闻 @drwwwg]

@SwuliusLab WOW，beautiful! I was here at the ACA meeting. Unfortunately I didn’t register for the M&M this year.

[Caltech @Caltech]

Congrats to @ehtelescope for creating the first-ever picture of Sgr A*, the black hole at the center of the Milky Way! The team included Caltech's @klbouman, who co-led one of the EHT teams (the imaging team) with colleagues from @MITHaystack & @IAA_CSIC. https://t.co/dH2hHJX6bu

[Wei_如是我闻 @drwwwg]

@gonenlab Same with@twitter comments

[Wei_如是我闻 @drwwwg]

@schong_ustc @MolecularCell Congrats！

[Slava Bobrov @slava__bobrov]

Neuron cells growing inside a zebrafish:
#neuroscience

[Tim Davison ᯅ @timd_ca]

Suddenly, a wild ribosome appears! This is my weekend project adding AR support to our custom renderer. There is much more still to do. What should I do with it? #ScreenshotSunday #gamedev #scicomm