Super proud of Rajesh and lab mates for this elegant study recently published in JCI! Our findings suggest redefining the way we think about cardiac macrophages in cardiovascular pathology. #MolkentinLab
Selective expansion of cardiac macrophage subtypes reveals nuanced roles https://t.co/Sb9eFP3hh2
Jeffery D. Molkentin & team @CincyChildrens's findings highlight the different contributions of tissue-resident versus monocyte-derived macrophages to cardiac health and disease.
In the image, an expanded population of tissue-resident macrophages (green) seek out necrotic cardiomyocytes (blue) in a dystrophic mouse model. #Fibrosis #CardiovascularDisease
Great new work from Molkentin lab: MCU complex deletion does not prevent mitochondrial Ca2+ overload and pathological mitochondrial permeability transition in a mouse model of DMD. https://t.co/ENlWmKdatc
Dr. Jeff Molkentin and colleagues from @CincyChildrens reported that MCUb is an inducible control point in regulating #skeletal muscle mitochondrial Ca2+ levels and substrate utilization that impacts total metabolic balance. ⚖️
🔎 https://t.co/4kzZ9wRLvl
#BCVS2019 ➡️ UC 2023
It was a delight being able to catch an insightful seminar from @HundLab and see great progress on the βIV-spectrin project! Go Bucks 🌰
We’re honored to be named the #1 children’s hospital in the nation according to @usnews! This is another amazing first for Cincinnati Children’s and our region and we couldn’t have gotten here without you. #WeAreCincyKids
Allow me to introduce myself: Dr. Dominique Tanner! The second Black woman to earn a PhD in Biomedical Engineering from the University of Cincinnat @uofcincy@UC_CEAS!
Proud of my team! Check out our newest publication @JMCCardiology "The lack of Troponin I Ser-23/24 phosphorylation is detrimental to in vivo cardiac function and exacerbates cardiac disease" https://t.co/LYQpYZ5siP