Even Holth Rustad

Hematology fellow & immuno-oncology researcher @oslounivsykehus | Cell & gene therapy dev | Former @MSKCancerCenter myeloma | Learn, share, do no harm

[Francesco Maura @FrancescoMaura4]

New preprint out today on @biorxivpreprint:"Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma"! Another study from our fantastic collaboration with @HDMyeloma @MSKCancerCenter @SylvesterCancer @univmiami @MayoClinic @MayoMyeloma #mmsm #wgs Twittorial 🧵1/21

[nizar jacques bahlis @NBahlis]

SMM: Taking the narrow over the wide path https://t.co/jPBsZo5Dxv This is a plea (and not a criticism) to #msmm #myeloma community to heavily invest in genomic, immunogenomic & biomarkers studies to generate better classifiers of risk of progression or redefine SMM as MGUS or MM

[Richard McElreath 🐈‍⬛ @rlmcelreath]

Using excel to do calculations is like pipetting by mouth - convenient, usually fine, but sometimes you ingest an ectoparasite and lose $92 million

[Francesco Maura @FrancescoMaura4]

Excited to see our new paper entitled "Genomic Classification and Individualized Prognosis in Multiple Myeloma" out on @JCO_ASCO! A fantastic collaboration between @SylvesterCancer, @univmiami, @MSKCancerCenter, @nyulangone, @MoffittNews, @HDMyeloma and many others!! #mmsm (1/x)

[Nature Medicine @NatureMedicine]

Targeted depletion of TRBV9+ T cells induces remission in a single ankylosing spondylitis patient, with significant improvements in functional and mobility metrics #Immunotherapy #AnkylosingSpondylitis https://t.co/KXc0EL7nHv

[Pieter Meysman @chevaliersf]

What #Tcells are hiding in your #SingleCell data?
Plenty of existing tools that claim to address this challenge, but are they consistent? Our review is now out in @FrontImmunol , with thanks to @czi for funding!
https://t.co/sa7akF93Mg

[Even Holth Rustad @EHRustad]

@C_Askenberg Vi kunne hatt en konstruktiv diskusjon om vi legger inn for mange pasienter som har lav risiko for alvorlig sykdom. Men at vi kan legge inn færre (som må være målet?) uten noen risiko, det blir bare useriøst

[Even Holth Rustad @EHRustad]

@MalmbergLab @ebba_sohlberg @aktbjorklund Congrats, fantastic news🥳🍾

[ACIR @ACIR_org]

Foldvari et al. developed a pipeline to map TCR reactivity to the complete proteome to evaluate TCR candidates for clinical translation. https://t.co/WdNeSvQY3L @UniOslo_MED  @ChariteBerlin  @Jolweus #ImmunotherapyResearch

[Johanna Olweus @JOlweus]

Congrats to brilliant postdoc Zsofia Fôldvari on her paper outlining a much-needed strategy to select safe T-cell receptors! https://t.co/8HJRLYkpBZ A wonderful collaboration with M. Leisegang and team at @ChariteBerlin & our team @UniOslo_MED / @Oslounivsykehus . @Nature_NPJ

[Sigurdur Kristinsson @sykristinsson]

4 orals, 6 posters, 1 educational and 2 Abstract achievement awards at #ASH22 from the @iStopMM study (w/9 different presenters)!
We are ridiculously excited to share our results after screening >75,000 Icelanders for MGUS.
And we are just beginning!
#mmsm 🧵Abstracts:

[Prof. Devi Sridhar @devisridhar]

Academics agreeing to exciting new papers & projects…

[Eric Smith @ESmithMDPhD]

Our report of first-in-human GPRC5D-targeted CAR T cells for MM is out in NEJM! The trial was led by Sham Mailankody and could not be done without the amazing clinical, correlative science, stats, & cell manufacturing teams.
Happy to share our bench>bedside journey
1/10

[Even Holth Rustad @EHRustad]

@SandveGeir Very cool interdisciplinary approach, looking forward to read!

[Even Holth Rustad @EHRustad]

@Festlegen Dette gjelder dessverre bare mikrosatelitt-ustabil sykdom, som er en liten subgruppe hvor immunterapi har dramatisk effekt. Likevel kult!

[Elli Papaemmanuil, PhD @PapaemmanuilLab]

Feasibility of clinical whole genome and transcriptome sequencing (WGTS) in oncology. A 🧵 on our latest study published in Nature Communications today:https://t.co/6007GkYDAc

[Even Holth Rustad @EHRustad]

Fulltreffer om tilgang til nye dyre medisiner - en utfordring for helsesystemet som vi MÅ løse sammen for pasientene @ingvildkjerkol @Bekkemellem @sigridbratlie @IngridSRoss @Kreftforeningen https://t.co/bczoYcBELa

[Francesco Maura @FrancescoMaura4]

New preprint from the lab!! @BenDiamondMD & @BachisioZic tracked the life-history of therapy-related myeloid neoplasms using chemotherapy #mutationalsignatures. Great collaboration @DrOlaLandgren @SylvesterCancer @MSKCancerCenter @nyulangone #mmsm #leusm https://t.co/ocb5SgH2r8

[Muhammad Ali @muhammadali_uio]

After a multi-year effort from so many brilliant people involved in this project, I am excited to share our work published today in @NatureBiotech. @JOlweus @Irenegr5 @Oslounivsykehus @UniOslo https://t.co/jiUr4Auk6X

[Saad Z. Usmani MD MBA FASCO 🇺🇸🇵🇰 @szusmani]

This is an incredible time to be an #mmsm researcher and the Myeloma Service @sloan_kettering is hiring! #MedTwitter peeps, please see the link (https://t.co/O2GupC7qAU) for details and email me on [email protected] #CureMM @ASH_hematology @ASCO @ASTCT