Connor Brown

Post-doc with @waterargome, lover of nature, biochemist of water microbes, and an okay dancer. First gen.

[Connor Brown @env_biochem]

now live: how should we relate AR indicators in sewage to community resistance? one look at this issue using deep longitudinal metagenomics, modeling, and lots of bioinformatics @waterARGome @petervikesland @AyellaMM

[medRxiv @medrxivpreprint]

Metagenomics disentangles epidemiological and microbial ecological associations between community antibiotic use and antibiotic resistance indicators measured in sewage https://t.co/jGcpIhVaZW #medRxiv

[Connor Brown @env_biochem]

in metagenomics - the assembly graph. The resulting tool will help address a major bottleneck facing metagenomics for biological surveillance - particularly in how we address antibiotic resistance. Cheers to all involved. 2/2

[Connor Brown @env_biochem]

This is a really good paper (https://t.co/XtCwcZuNA2) and I'm proud to have contributed to its conception. Moumi took ownership of this project and taught herself much about one of the most challenging and complex topics (1/2)

[Uli Klümper @UliKluemper]

Our new @biorxivpreprint together with the German Environmental Agency (@Umweltbundesamt):

Suppressing selection for antibiotic resistance in the environment: A transparent, ecology-based approach to predicted no-effect concentrations

https://t.co/9myWaE1Lue

[Tominaga K. (tomiken) @pacyc1841]

Replication coordination marks the domestication of large extrachromosomal replicons in bacteria | bioRxiv https://t.co/eSlUQwfHpg

[Petr Kohout @Kohout_mycor]

You can now download the entire community matrix for ~83,000 samples (with metadata) and ~75,000 fungal taxa with just one click! Explore the GlobalFungi database.

[Joseph E. Peters @JoePetersLab]

Telomeric transposons are pervasive in linear bacterial genomes | Science https://t.co/BV0T7LrME6

[Keith Robison @OmicsOmicsBlog]

Roche SBX preprint out

https://t.co/C8TdNRrBMA

[Tominaga K. (tomiken) @pacyc1841]

RNA-guided nucleases enable a gene drive of insertion sequences in plasmids | bioRxiv https://t.co/EGF8fbmC7q

[Laura Chacon Machado @pomarros4]

Our preprint describing a family of Tn7-like transposons that evolved to target CRISPR repeats is now published at Mobile DNA #Tn7 #transposons #mobileDNA 1/10
https://t.co/nkMS5cslyY

[Connor Brown @env_biochem]

@vsbuffalo which I'm sure you agree with for the most part- but I guess my point is that lack of scientific literacy is a major factor. 2/2

[Connor Brown @env_biochem]

@vsbuffalo I feel there's always been shoddy studies, but science itself is about consensus- many studies over a long period of time- I think we should question whether ever blithely throwing out "X article" supports whatever opinion is valid. Even very good science can be wrong. 1/2

[Connor Brown @env_biochem]

mobileOG-db 2.0 pre-release available if anyone is still on twitter https://t.co/jYaLbk0r6n
let us know your thoughts #microbiome #mobilegeneticelements #phages #plasmids #etc

[Joint Genome Institute @jgi]

In Science Advances: a microbial genome census from publicly available databases using publicly available genome sequence data generated over the past three decades.

@kyrpides @IMG_DATA @doescience

https://t.co/4v6iy5Biwp

[David Coil @davidacoil]

Currently reading the very interesting "Ebolavirus evolution and emergence are associated with land use change"... a nice mix of phylogenetic analysis combined with broader ecological factors. https://t.co/75kJ6PMIxa

[Tominaga K. (tomiken) @pacyc1841]

» Homologous recombination shapes the architecture and evolution of bacterial genomes | Nucleic Acids Research | Oxford Academic https://t.co/r21um0ZWUm

[Connor Brown @env_biochem]

@AllisonLopatkin @NSF amazing, so deserved!

[ASM @ASMicrobiology]

Exciting news! ASM is partnering with @IDSAInfo to launch an annual conference on #AMR. This landmark event will unite experts from academia & industry to collaborate and respond to the urgent need for novel antimicrobial solutions. Read the announcement: https://t.co/WFN87tcoSX

[npj Antimicrobials and Resistance @npjAMR]

Antibiotic resistance mediated by gene amplifications🧬

This review is available open-access to read @npjAMR!

@kptsilva @AnuKhareLab

(1/5)

https://t.co/KBW2xALvLm

[Jingqiu Liao @JingqiuLiao]

Thrilled to share that the FIRST paper from our group is live in @NatureComms ! Kudos to my amazing students @yingxian_g , Balu, and Anthony and all the collaborators. And thanks @VTCeZAP for the support!